Aqueous solutions containing amino acids and peptides. Part 28.—Enthalpy of interaction of some amides with glycine and α-alanine: interactions of the zwitterionic group of α-amino acids with hydrophobic groups and peptide groups

1992 ◽  
Vol 88 (17) ◽  
pp. 2503-2509 ◽  
Author(s):  
Javier Fernandez ◽  
Terence H. Lilley
Author(s):  
S.A.C. Gould ◽  
B. Drake ◽  
C.B. Prater ◽  
A.L. Weisenhorn ◽  
S.M. Lindsay ◽  
...  

The atomic force microscope (AFM) is an instrument that can be used to image many samples of interest in biology and medicine. Images of polymerized amino acids, polyalanine and polyphenylalanine demonstrate the potential of the AFM for revealing the structure of molecules. Images of the protein fibrinogen which agree with TEM images demonstrate that the AFM can provide topographical data on larger molecules. Finally, images of DNA suggest the AFM may soon provide an easier and faster technique for DNA sequencing.The AFM consists of a microfabricated SiO2 triangular shaped cantilever with a diamond tip affixed at the elbow to act as a probe. The sample is mounted on a electronically driven piezoelectric crystal. It is then placed in contact with the tip and scanned. The topography of the surface causes minute deflections in the 100 μm long cantilever which are detected using an optical lever.


2003 ◽  
Vol 32 (11) ◽  
pp. 977-985 ◽  
Author(s):  
Huaji Liu ◽  
Ruisen Lin ◽  
Honglin Zhang

2012 ◽  
Vol 46 (4) ◽  
pp. 235-240 ◽  
Author(s):  
A. A. Sladkova ◽  
A. A. Sosnovskaya ◽  
I. P. Edimecheva ◽  
V. A. Knizhnikov ◽  
O. I. Shadyro

1994 ◽  
Vol 27 (4) ◽  
pp. 219-224
Author(s):  
V. Arulmozhi ◽  
A. Srinivasa Rao

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