Conformation and reactivity. Part VII. Kinetics of the alkaline hydrolysis of the methyl and ethyl trans-decalincarboxylates, and 4-t-butylcyclohexanecarboxylates, certain trans-4-substituted cyclohexanecarboxylates, and methyl and ethyl cyclohexanecarboxylate in alcohol–water and dioxan–water mixtures

The kinetics of alkaline hydrolysis of 3,4-thiophenedicarboxylic acid monomethyl ester has been studied in mixed solvents water-methyl alcohol, water-tert-butyl alcohol, and water-dioxane. The specific effects causing different courses of these dependences have been evaluated. The greatest changes in the thermodynamic activation parameters have been observed in the medium of water-methyl alcohol.

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Solvent effects on the kinetics of alkaline hydrolysis of dimethylacetylacetone. Part I. Influence of alcohol–water mixtures

Journal of the Chemical Society Perkin Transactions 2 ◽

10.1039/p29720000706 ◽

1972 ◽

pp. 706-710 ◽

Cited By ~ 3

Author(s):

Jean-Pierre Calmon ◽

Jean-Louis Canavy

Keyword(s):

Solvent Effects ◽

Alkaline Hydrolysis ◽

Alcohol Water ◽

Kinetics Of ◽

Hydrolysis Of

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Influence of medium on alkaline hydrolysis of succinic acid monomethyl and monopropyl esters

Collection of Czechoslovak Chemical Communications ◽

10.1135/cccc19802873 ◽

1980 ◽

Vol 45 (11) ◽

pp. 2873-2882

Author(s):

Vladislav Holba ◽

Ján Benko

Keyword(s):

Succinic Acid ◽

Kinetic Parameters ◽

Alkaline Hydrolysis ◽

Specific Interactions ◽

Nonaqueous Media ◽

The Media ◽

Kinetics Of ◽

Hydrolysis Of

The kinetics of alkaline hydrolysis of succinic acid monomethyl and monopropyl esters were studied in mixed aqueous-nonaqueous media at various temperatures and ionic strengths. The results of measurements are discussed in terms of electrostatic and specific interactions between the reactants and other components of the reaction mixture. The kinetic parameters in the media under study are related to the influence of the cosolvent on the solvation sphere of the reactants.

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The Kinetics of the Acidic and Alkaline Hydrolysis of Ethyl Thionbenzoate

The Journal of Organic Chemistry ◽

10.1021/jo01045a081 ◽

1963 ◽

Vol 28 (10) ◽

pp. 2825-2828 ◽

Cited By ~ 7

Author(s):

Stanley G. Smith ◽

Marion O'Leary

Keyword(s):

Alkaline Hydrolysis ◽

Kinetics Of ◽

Hydrolysis Of

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Isothermal and non-isothermal kinetics of hydrolysis of 1-[2-(2- pentyloxyphenylcarbamoyloxy)-(2-methoxymethyl)-ethyl]- perhydroazepinium chloride (BK 129)

Acta Facultatis Pharmaceuticae Universitatis Comenianae ◽

10.2478/afpuc-2013-0018 ◽

2013 ◽

Vol 60 (2) ◽

pp. 43-48

Author(s):

Stankovičová M. ◽

Bezáková Ž. ◽

Beňo P. ◽

Húšťavová P.

Keyword(s):

Biological Activity ◽

Alkaline Hydrolysis ◽

Functional Group ◽

Isothermal Kinetics ◽

Basic Part ◽

Buffer Solutions ◽

Kinetics Of Hydrolysis ◽

Short Time ◽

Kinetics Of ◽

Hydrolysis Of

Abstract The substance BK 129 - 1-[2-(2-pentyloxyphenylcarbamoyloxy)-(2-methoxymethyl)-ethyl]-perhydroazepinium chloride was prepared in terms of influence of the connecting chain between the carbamate functional group and the basic part of molecule on biological activity. Such a structural feature is important with regard to its stability. In this work we determined the rate constants of alkaline hydrolysis of this compound at increased temperature under isothermal and non-isothermal conditions. The hydrolysis was also performed in buffer solutions with the purpose of evaluating its stability. Non-isothermal tests of stability enable to reduce the number of analyses. The necessary data for stability of compound are in this way achieved in a short time.

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