Asymmetric synthesis ofL-[3-11C]alanine andL-[3-11C]phenylalanine by a phase-transfer alkylation reaction

1988 ◽  
pp. 3081-3084 ◽  
Author(s):  
Karl-Johan Fasth ◽  
Gunnar Antoni ◽  
Bengt Langström
Keyword(s):  
Asymmetric Synthesis ◽  
Phase Transfer ◽  
Alkylation Reaction

ChemInform Abstract: Chiral Salen-Metal Complexes as Novel Catalysts for the Asymmetric Synthesis of α-Amino Acids under Phase Transfer Catalysis Conditions.

ChemInform ◽  
2010 ◽  
Vol 32 (30) ◽  
pp. no-no
Author(s):  
Yuri N. Belokon ◽  
Michael North ◽  
Tatiana D. Churkina ◽  
Nikolai S. Ikonnikov ◽  
Victor I. Maleev
Keyword(s):  
Amino Acids ◽  
Metal Complexes ◽  
Asymmetric Synthesis ◽  
Phase Transfer Catalysis ◽  
Phase Transfer

scholarly journals A Remarkably Efficient Phase-Transfer Catalyzed Amination of α-Bromo-α, β-Unsaturated Ketones in Water

2021 ◽  
Vol 2021 ◽  
pp. 1-10
Author(s):  
Alemayehu Mekonnen ◽  
Alemu Tesfaye
Keyword(s):  
Quaternary Ammonium ◽  
Phase Transfer ◽  
Conjugate Addition ◽  
Quaternary Ammonium Salts ◽  
Cinchona Alkaloids ◽  
Ammonium Salts ◽  
Alkylation Reaction ◽  
Pt Catalysts ◽  
Unsaturated Ketones ◽  
Catalytic Performances

Tandem conjugate addition–alkylation reaction of various amines with α-bromo-α, β-unsaturated ketones resulted in near-quantitative conversions into the corresponding aziridines when the reaction was carried out in the presence of 10 mol% of phase-transfer, PT catalysts in water. Some chiral quaternary ammonium salts derived from Cinchona alkaloids were investigated as water-stable PT catalysts. The scope and limitations of the reaction have also been investigated. The catalytic performances were significantly improved in comparison with the corresponding ordinary quaternary ammonium salt catalysts, and excellent yields (81%–96%) were obtained. Although an increase in the rate of aziridination has been accomplished, no stereoselectivity was observed. The positive values of the protocol have been confirmed.

The mechanism of phase transfer in the O-alkylation reaction of diols

2008 ◽  
Vol 48 (6) ◽  
pp. 434-439
Author(s):  
N. V. Morozova ◽  
N. N. Lebedeva ◽  
L. P. Panicheva
Keyword(s):  
Phase Transfer ◽  
Alkylation Reaction

Asymmetric Synthesis of α,β-Epoxysulfones via Phase-Transfer Catalytic Darzens Reaction.

ChemInform ◽  
2007 ◽  
Vol 38 (48) ◽  
Author(s):  
Jin-Mo Ku ◽  
Mi-Sook Yoo ◽  
Hyeung-geun Park ◽  
Sang-sup Jew ◽  
Byeong-Seon Jeong
Keyword(s):  
Asymmetric Synthesis ◽  
Phase Transfer ◽  
Darzens Reaction

scholarly journals Asymmetric tandem hemiaminal-heterocyclization-aza-Mannich reaction of 2-formylbenzonitriles and amines using chiral phase transfer catalysis: an experimental and theoretical study

RSC Advances ◽  
2016 ◽  
Vol 6 (38) ◽  
pp. 31861-31870 ◽  
Author(s):  
Amedeo Capobianco ◽  
Antonia Di Mola ◽  
Valentina Intintoli ◽  
Antonio Massa ◽  
Vito Capaccio ◽  
...  
Keyword(s):  
Asymmetric Synthesis ◽  
Mannich Reaction ◽  
Phase Transfer Catalysis ◽  
Theoretical Study ◽  
Phase Transfer ◽  
Chiral Phase

The first asymmetric synthesis of 3-amino-substituted isoindolinones was accomplished via cascade hemiaminal-heterocyclization-intramolecular aza-Mannich reaction of amines and 2-formylbenzonitriles using chiral phase transfer conditions (PTC).

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