scholarly journals A mouse gene family associated with a major submaxillary-gland glycoprotein

1985 ◽  
Vol 225 (3) ◽  
pp. 657-663 ◽  
Author(s):  
A G Craig ◽  
J J Mullins ◽  
P McTurk ◽  
W J Brammar
Keyword(s):  
Gene Family ◽  
Submaxillary Gland ◽  
Major Product ◽  
Mouse Gene ◽  
Southern Analysis ◽  
Oligonucleotide Probes ◽  
Genomic Cloning ◽  
Mouse Submaxillary Gland ◽  
Physical Linkage

A gene family encoding msp36 (mouse submaxillary protein 36), a major product of the mouse submaxillary gland, was shown by Southern analysis and genomic cloning to contain approx. 10 related genes. Heteroduplex mapping has elucidated the structure of one of the genes. Close physical linkage of four of the genes in this family has been demonstrated by the use of specific oligonucleotide probes.

Nucleotide sequences of liver, lachrymal, and submaxillary gland mouse major urinary protein mRNAs: mosaic structure and construction of panels of gene-specific synthetic oligonucleotide probes

1987 ◽  
Vol 7 (5) ◽  
pp. 1938-1946
Author(s):  
K Shahan ◽  
M Gilmartin ◽  
E Derman
Keyword(s):  
Gene Family ◽  
Sequence Data ◽  
Submaxillary Gland ◽  
Nucleotide Sequences ◽  
Oligonucleotide Probes ◽  
Mrna Species ◽  
Major Urinary Proteins ◽  
Synthetic Oligonucleotide ◽  
The Individual ◽  
Distinct Member

The mouse major urinary proteins (MUPs) are encoded by a gene family of about 35 to 40 members. MUPs are synthesized in at least six secretory tissues under a variety of developmental and endocrine controls, but the identities of the individual genes expressed in each tissue have not previously been established. In this article, we present the nucleotide sequences of five MUP mRNAs which we designate MUP I through V. MUPs I, II, and III are the most abundant MUP mRNA species in the liver, and MUPs IV and V are the most abundant MUP mRNA species in the lachrymal gland and the submaxillary gland, respectively. The sequence data show that each of the five mRNAs is encoded by a distinct member of the gene family. The structures of the MUP mRNA consist of interspersed segments of variable and conserved sequences. On the basis of the sequences of the variable segments, gene-specific panels of synthetic oligonucleotide probes were prepared. The gene-specific panels were used to identify cloned genes and, as described in the accompanying paper (K. Shahan, M. Denaro, M. Gilmartin, Y. Shi, and E. Derman, Mol. Cell. Biol. 7:1947-1954, 1987), to characterize the expression of MUP genes I through V.

scholarly journals Nucleotide sequences of liver, lachrymal, and submaxillary gland mouse major urinary protein mRNAs: mosaic structure and construction of panels of gene-specific synthetic oligonucleotide probes.

1987 ◽  
Vol 7 (5) ◽  
pp. 1938-1946 ◽  
Author(s):  
K Shahan ◽  
M Gilmartin ◽  
E Derman
Keyword(s):  
Gene Family ◽  
Sequence Data ◽  
Submaxillary Gland ◽  
Nucleotide Sequences ◽  
Oligonucleotide Probes ◽  
Mrna Species ◽  
Major Urinary Proteins ◽  
Synthetic Oligonucleotide ◽  
The Individual ◽  
Distinct Member

The mouse major urinary proteins (MUPs) are encoded by a gene family of about 35 to 40 members. MUPs are synthesized in at least six secretory tissues under a variety of developmental and endocrine controls, but the identities of the individual genes expressed in each tissue have not previously been established. In this article, we present the nucleotide sequences of five MUP mRNAs which we designate MUP I through V. MUPs I, II, and III are the most abundant MUP mRNA species in the liver, and MUPs IV and V are the most abundant MUP mRNA species in the lachrymal gland and the submaxillary gland, respectively. The sequence data show that each of the five mRNAs is encoded by a distinct member of the gene family. The structures of the MUP mRNA consist of interspersed segments of variable and conserved sequences. On the basis of the sequences of the variable segments, gene-specific panels of synthetic oligonucleotide probes were prepared. The gene-specific panels were used to identify cloned genes and, as described in the accompanying paper (K. Shahan, M. Denaro, M. Gilmartin, Y. Shi, and E. Derman, Mol. Cell. Biol. 7:1947-1954, 1987), to characterize the expression of MUP genes I through V.

scholarly journals Preliminary X-ray crystallographic data on mouse submaxillary gland renin and renin-inhibitor complexes.

1984 ◽  
Vol 259 (20) ◽  
pp. 12714-12717
Author(s):  
M A Navia ◽  
J P Springer ◽  
M Poe ◽  
J Boger ◽  
K Hoogsteen
Keyword(s):  
Submaxillary Gland ◽  
Crystallographic Data ◽  
Renin Inhibitor ◽  
X Ray ◽  
Mouse Submaxillary Gland

Mesenchymal control over elongating and branching morphogenesis in salivary gland development

Development ◽  
1981 ◽  
Vol 66 (1) ◽  
pp. 209-221
Author(s):  
Hiroyuki Nogawa ◽  
Takeo Mizuno
Keyword(s):  
Salivary Gland ◽  
Salivary Glands ◽  
Submaxillary Gland ◽  
Branching Morphogenesis ◽  
Mouse Submaxillary Gland ◽  
Gland Development

Recombination of the epithelium and mesenchyme between quail anterior submaxillary gland (elongating type) and quail anterior lingual or mouse submaxillary gland (branching type) was effected in vitro to clarify whether the elongating morphogenesis was directed by the epithelial or the mesenchymal component. Quail anterior submaxillary epithelium recombined with quail anterior lingual or mouse submaxillary mesenchyme came to branch. Conversely, quail anterior lingual or 12-day mouse submaxillary epithelium recombined with quail anterior submaxillary mesenchyme came to elongate, though the mesenchyme was less effective with 13-day mouse submaxillary epithelium. These results suggest that the elongating or branching morphogenesis of quail salivary glands is controlled by the mesenchyme.

Rapid and large-scale purification and characterization of renin from mouse submaxillary gland

1982 ◽  
Vol 217 (2) ◽  
pp. 574-581 ◽  
Author(s):  
Kunio S. Misono ◽  
Leslie A. Holladay ◽  
Kazuo Murakami ◽  
Kenji Kuromizu ◽  
Tadashi Inagami
Keyword(s):  
Large Scale ◽  
Submaxillary Gland ◽  
Purification And Characterization ◽  
Mouse Submaxillary Gland

Biological activities in the granules isolated from the mouse submaxillary gland

1974 ◽  
Vol 86 (2) ◽  
pp. 233-236 ◽  
Author(s):  
F. Pasquini ◽  
Anna Petris ◽  
G. Sbaraglia ◽  
R. Scopelliti ◽  
G. Cenci ◽  
...  
Keyword(s):  
Biological Activities ◽  
Submaxillary Gland ◽  
Mouse Submaxillary Gland
Sign in / Sign up

Export Citation Format

Share Document