Denaturation transition of stretched DNA
2013 ◽
Vol 41
(2)
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pp. 639-645
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Keyword(s):
In the last two decades, single-molecule force measurements using optical and magnetic tweezers and atomic force spectroscopy have dramatically expanded our knowledge of nucleic acids and proteins. These techniques characterize the force on a biomolecule required to produce a given molecular extension. When stretching long DNA molecules, the observed force–extension relationship exhibits a characteristic plateau at approximately 65 pN where the DNA may be extended to almost twice its B-DNA length with almost no increase in force. In the present review, I describe this transition in terms of the Poland–Scheraga model and summarize recent related studies.
2004 ◽
Vol 18
(2)
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pp. 203-211
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2015 ◽
Vol 119
(42)
◽
pp. 13278-13287
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2014 ◽
Vol 54
◽
pp. 492-498
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Keyword(s):
2009 ◽
Vol 18
(1)
◽
pp. 141-151
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2008 ◽
Vol 377
(3)
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pp. 706-714
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