Vitamin D Deficiency in the Osteomalacia of Chronic Renal Failure

1977 ◽  
Vol 52 (2) ◽  
pp. 29P-29P
Author(s):  
J. B. Eastwood ◽  
E. Harris ◽  
T. C. B. Stamp ◽  
H. E. de Wardener
Keyword(s):  
Vitamin D ◽  
Renal Failure ◽  
Chronic Renal Failure ◽  
Vitamin D Deficiency

scholarly journals PREVALENCE OF VITAMIN D DEFICIENCY IN DIFFERENT GROUPS OF CHRONIC RENAL FAILURE PATIENTS

2015 ◽  
Vol 21 (3) ◽  
pp. 887-890 ◽  
Author(s):  
Bistra T. Galunska ◽  
◽  
Daniela I. Gerova ◽  
Dobrin N. Paskalev ◽  
Rositza Y. Zorcheva ◽  
...  
Keyword(s):  
Vitamin D ◽  
Renal Failure ◽  
Chronic Renal Failure ◽  
Vitamin D Deficiency

Hypocalcaemia: Differential Diagnosis and Investigation

1976 ◽  
Vol 13 (1-6) ◽  
pp. 578-584 ◽  
Author(s):  
C. R. Paterson
Keyword(s):  
Vitamin D ◽  
Renal Failure ◽  
Differential Diagnosis ◽  
Chronic Renal Failure ◽  
Vitamin D Deficiency ◽  
The World

Hypocalcaemia accounts for many of the telephone inquiries made to the Department of Biochemical Medicine in Dundee. About half of these cases can be explained by hypoalbuminaemia; the causes of “true” hypocalcaemia are given in Table 1. Chronic renal failure is probably the most frequent cause of hypocalcaemia in Britain. In the world as a whole it is likely that vitamin D deficiency, causing rickets in children and osteomalacia in adults, is the commonest cause of hypocalcaemia.

Clinical evaluation of two parathyroid hormone assays in the context of vitamin D supply in chronic kidney disease

2013 ◽  
Vol 154 (51) ◽  
pp. 2025-2036
Author(s):  
László Kovács ◽  
Éva Virágh ◽  
Dóra Balogh ◽  
Bernadette Kálmán ◽  
Zoltán Lőcsei ◽  
...  
Keyword(s):  
Chronic Kidney Disease ◽  
Vitamin D ◽  
Renal Failure ◽  
Peritoneal Dialysis ◽  
Parathyroid Hormone ◽  
Chronic Renal Failure ◽  
Vitamin D Deficiency ◽  
Intact Parathyroid Hormone ◽  
Hormone Levels ◽  
The Difference

Introduction: Parathyroid hormone levels provide important information in chronic renal failure. Aim: To compare parathyroid hormone levels measured by two assays in correlation with vitamin D supply. Method: Parathyroid hormone and 25-hydroxi-vitamin-D were determined in 104 patients (31 patients with chronic renal failure without renal replacement therapy, 36 patients treated with peritoneal dialysis and 37 patients treated with hemodialysis). Results: Good correlation was found between results of the two parathyroid hormone methods, but the intact parathyroid hormone levels were higher than the biointact values. 87% and 13% of the patients had vitamin-D deficiency and insufficiency, respectively. The frequency of serious vitamin-D deficiency was higher in the peritoneal dialysis than in the hemodialysis group. Intact parathyroid hormone levels were different in dialysed patients having vitamin-D-deficiency and insufficiency, and the difference was higher for the biointact than intact values. Negative correlation was detected between biointact parathyroid hormone and 25-hydroxivitamin-D in the hemodialysis group. Conclusions: Biointact parathyroid hormone levels better reflect the vitamin D supply and bone metabolism than intact levels, especially in hemodialysed patients. Orv. Hetil., 2013, 154(51), 2025–2036.

Distribution of Circulating Immunoreactive Components of Parathyroid Hormone in Normal Subjects and in Patients with Primary and Secondary Hyperparathyroidism: The Role of the Kidney and of the Serum Calcium Concentration

1979 ◽  
Vol 57 (5) ◽  
pp. 435-443 ◽  
Author(s):  
M. A. Dambacher ◽  
J. A. Fischer ◽  
W. H. Hunziker ◽  
W. Born ◽  
J. Moran ◽  
...  
Keyword(s):  
Vitamin D ◽  
Renal Failure ◽  
Parathyroid Hormone ◽  
Chronic Renal Failure ◽  
Primary Hyperparathyroidism ◽  
Vitamin D Deficiency ◽  
Normal Subjects ◽  
Dependent Manner ◽  
Intact Pth ◽  
Calcium Dependent

1. The distribution of intact parathyroid hormone-(1–84) [PTH-(1–84)] and of its COOH-terminal fragments was determined in human serum by column chromatography. In addition to PTH-(1–84) (peak I), COOH-terminal fragments having molecular weights of approximately 4000–7000 (peak II) and immunoreactive components co-eluting with human PTH-(1–12) (peak III) were observed. 2. Mean concentrations of intact PTH-(1–84) and of its COOH-terminal fragments were significantly raised in chronic renal failure as compared with those of normal subjects. Mean amounts of peak II were higher in patients with chronic renal insufficiency than in nutritional vitamin D deficiency, in pseudohypoparathyroidism and in primary hyperparathyroidism, despite comparable amounts of PTH-(1–84). 3. In chronic renal failure as well as in a group of patients with vitamin D deficiency, pseudohypoparathyroidism and primary hyperparathyroidism and in controls, significant linear relations were found between the serum concentrations of calcium and log (peak II/peak I). Our findings suggest that the conversion of intact PTH-(1–84) into COOH-terminal fragments by the parathyroid glands (resulting in a raised secretion of fragments) and/or in peripheral organs may be directly related to the serum concentration of calcium. However, the degradation of the fragments may also be suppressed in a calcium-dependent manner.

VITAMIN-D DEFICIENCY IN CHRONIC RENAL FAILURE

The Lancet ◽  
1977 ◽  
Vol 309 (8002) ◽  
pp. 100
Author(s):  
GeraldA. MacGregor
Keyword(s):  
Vitamin D ◽  
Renal Failure ◽  
Chronic Renal Failure ◽  
Vitamin D Deficiency

VITAMIN-D DEFICIENCY IN THE OSTEOMALACIA OF CHRONIC RENAL FAILURE

The Lancet ◽  
1976 ◽  
Vol 308 (7997) ◽  
pp. 1209-1211 ◽  
Author(s):  
J.B. Eastwood ◽  
T.C.B. Stamp ◽  
E. Harris ◽  
H.E. De Wardener
Keyword(s):  
Vitamin D ◽  
Renal Failure ◽  
Chronic Renal Failure ◽  
Vitamin D Deficiency

Severe vitamin D deficiency in chronic renal failure patients on peritoneal dialysis

2006 ◽  
Vol 66 (10) ◽  
pp. 247-255 ◽  
Author(s):  
H. Taskapan ◽  
F.F. Ersoy ◽  
P.S. Passadakis ◽  
P. Tam ◽  
D.E. Memmos ◽  
...  
Keyword(s):  
Vitamin D ◽  
Renal Failure ◽  
Peritoneal Dialysis ◽  
Chronic Renal Failure ◽  
Vitamin D Deficiency ◽  
Severe Vitamin

Absorption of phosphate in the jejunum of patients with chronic renal failure before and after correction of vitamin D deficiency

1983 ◽  
Vol 85 (4) ◽  
pp. 908-916 ◽  
Author(s):  
Glenn R. Davis ◽  
Joseph E. Zerwekh ◽  
Tom F. Parker ◽  
Guenter J. Krejs ◽  
C.Y.C. Pak ◽  
...  
Keyword(s):  
Vitamin D ◽  
Renal Failure ◽  
Chronic Renal Failure ◽  
Vitamin D Deficiency ◽  
Before And After
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