Assessment of Myocardial Reinnervation in Cardiac Transplants by Positron Emission Tomography: Functional Significance Tested by Heart Rate Variability

1996 ◽  
Vol 91 (s1) ◽  
pp. 126-128 ◽  
Author(s):  
Sibylle I. Ziegler ◽  
Axel W. Frey ◽  
Peter überfuhr ◽  
Martin Dambacher ◽  
Petra Watzlowik ◽  
...  
1998 ◽  
Vol 18 (2) ◽  
pp. 141-147 ◽  
Author(s):  
Robert C. Coghill ◽  
Christine N. Sang ◽  
Karen Faith Berman ◽  
Gary J. Bennett ◽  
Michael J. Iadarola

Positron emission tomography studies have identified a common set of brain regions activated by pain. No studies, however, have quantitatively examined pain-induced CBF changes. To better characterize CBF during pain, 14 subjects received positron emission tomography scans during rest, during capsaicin-evoked pain (250 μg, intradermal injection), and during innocuous vibration. Using the H215O intravenous bolus method with arterial blood sampling, global CBF changes were assessed quantitatively. Painful stimulation produced a 22.8% decrease in global CBF from resting levels ( P < 0.0005). This decrease was not accounted for by arterial PCO2 or heart rate changes. Although the exact mechanism remains to be determined, this pain-induced global decrease represents a previously unidentified response of CBF.


1994 ◽  
Author(s):  
Bertha K. Madras ◽  
◽  
David R. Elmaleh ◽  
Peter C. Meltzer ◽  
Anna Y. Liung ◽  
...  

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