Commitment to Theory

1994 ◽  
Vol 3 (2) ◽  
pp. 30-34 ◽  
Author(s):  
Sandy Friel-Patti
Keyword(s):  
Treatment Efficacy ◽  
Professional Community ◽  
Communication Disorders ◽  
Data Driven ◽  
Objective Data ◽  
Auditory Integration Training ◽  
Peer Reviewers ◽  
Auditory Integration ◽  
Professional Review

In summary, authors Rimland, Edelson, and Veale are to be commended for bringing the topic of auditory integration training forward for professional review and debate. AIT offers an excellent forum for consideration of the role of theory in intervention for clinicians engaged in treatment of persons with communication disorders. Each clinician must take a step back on occasion and face the question about treatment efficacy from an objective, data-driven perspective. Such public discussion of AIT as intervention inevitably leads to reexamination of what is meant by success/failure in treatment; indeed, what constitutes intervention itself. AIT is being held up to the scrutiny of both the clinical and research communities, and, if it is valid, it will withstand such inquiry and will even advance our understanding of some very perplexing disorders. In order for that to happen, responsible researchers and clinicians must be willing to shed biases, ask questions, conduct studies, and report them to their professional community of peer reviewers. The process is vital for every speech, language, and hearing professional and for the persons with communication disorders they serve.

Maximum Output Intensity of the Audiokinetron

1996 ◽  
Vol 5 (2) ◽  
pp. 68-72 ◽  
Author(s):  
Christine M. Rankovic ◽  
William M. Rabinowitz ◽  
Gregory L. Lof
Keyword(s):  
Developmental Disabilities ◽  
Maximum Output ◽  
Output Intensity ◽  
Safety Studies ◽  
Auditory Integration Training ◽  
Auditory Integration

The Audiokinetron is a device that processes music for earphone presentation to patients undergoing auditory integration training, a treatment for individuals with autism and other developmental disabilities. Intensity levels produced by the Audiokinetron were measured under realistic listening conditions with a KEMAR manikin substituted for a patient. Average levels at the eardrum were 110 dB SPL when the device was adjusted to the highest setting employed by a local, trained AIT practitioner and 118 dB SPL at the maximum setting of the device. These levels are potentially harmful to hearing and warrant further safety studies of AIT instruments and protocols.

Natural Phenomena and the Primacy of Experiment

2018 ◽  
Author(s):  
Massimiliano Di Ventra
Keyword(s):  
Objective Data ◽  
Natural Phenomena ◽  
Material World

This chapter defines what phenomena and objective data are and how the latter ones are obtained, and explains the fundamental role of experiments in obtaining information on the material world.

scholarly journals Out of the loop? On the radical and the routine in urban big data

Urban Studies ◽  
2021 ◽  
pp. 004209802110140
Author(s):  
Sarah Barns
Keyword(s):  
Artificial Intelligence ◽  
Big Data ◽  
Computational Models ◽  
Data Driven ◽  
Urban Systems ◽  
Out Of The Loop ◽  
Urban Futures ◽  
Urban Behaviour ◽  
The City

This commentary interrogates what it means for routine urban behaviours to now be replicating themselves computationally. The emergence of autonomous or artificial intelligence points to the powerful role of big data in the city, as increasingly powerful computational models are now capable of replicating and reproducing existing spatial patterns and activities. I discuss these emergent urban systems of learned or trained intelligence as being at once radical and routine. Just as the material and behavioural conditions that give rise to urban big data demand attention, so do the generative design principles of data-driven models of urban behaviour, as they are increasingly put to use in the production of replicable, autonomous urban futures.

scholarly journals DNA methylation as predictive marker of response to immunotherapy?

2021 ◽  
Author(s):  
Gerwin Heller
Keyword(s):  
Dna Methylation ◽  
Cancer Treatment ◽  
Treatment Efficacy ◽  
Predictive Marker ◽  
Short Review ◽  
Predictive Markers ◽  
Epigenetic Factors

SummaryImmunotherapy is one of the major breakthroughs in cancer treatment. However, many patients do not benefit from this type of therapy. Thus, there is an urgent need for a strategy to predict treatment efficacy before start of therapy. The role of certain genetic and epigenetic factors as potential predictive markers for response to immunotherapy is discussed in this short review.

scholarly journals Transkingdom interactions between Lactobacilli and hepatic mitochondria attenuate western diet-induced diabetes

2021 ◽  
Vol 12 (1) ◽  
Author(s):  
Richard R. Rodrigues ◽  
Manoj Gurung ◽  
Zhipeng Li ◽  
Manuel García-Jaramillo ◽  
Renee Greer ◽  
...  
Keyword(s):  
Functional Role ◽  
Reduced Glutathione ◽  
Western Diet ◽  
Data Driven ◽  
Data Driven Approach ◽  
Probiotic Strains ◽  
Host Metabolism ◽  
Harmful Effects

AbstractWestern diet (WD) is one of the major culprits of metabolic disease including type 2 diabetes (T2D) with gut microbiota playing an important role in modulating effects of the diet. Herein, we use a data-driven approach (Transkingdom Network analysis) to model host-microbiome interactions under WD to infer which members of microbiota contribute to the altered host metabolism. Interrogation of this network pointed to taxa with potential beneficial or harmful effects on host’s metabolism. We then validate the functional role of the predicted bacteria in regulating metabolism and show that they act via different host pathways. Our gene expression and electron microscopy studies show that two species from Lactobacillus genus act upon mitochondria in the liver leading to the improvement of lipid metabolism. Metabolomics analyses revealed that reduced glutathione may mediate these effects. Our study identifies potential probiotic strains for T2D and provides important insights into mechanisms of their action.

Big data-driven supply chain and performance: a resource-based view

2021 ◽  
Vol ahead-of-print (ahead-of-print) ◽  
Author(s):  
Shampy Kamboj ◽  
Shruti Rana
Keyword(s):  
Big Data ◽  
Supply Chain ◽  
Small And Medium Enterprises ◽  
Data Driven ◽  
Equation Modeling ◽  
Firm Age ◽  
Content Type ◽  
Sustainable Performance ◽  
Medium Enterprises

PurposeThe main objective of this paper is to study the role of supply chain performance (SCP) as a mediator between big data-driven supply chain (BDDSC) and firm sustainable performance. In addition, the role of firm age as a moderator between BDDSC and SCP as well as between SCP and firm sustainable performance has also been explored.Design/methodology/approachThe 200 managers of medium or senior level positions in micro, small and medium enterprises (MSMEs) located at Delhi-NCR have been contacted. Further, collected data have been confirmed with confirmatory factor analysis (CFA). In this paper, structure equation modeling (SEM) has been employed to empirically check the proposed hypotheses and their relationships.FindingsThe findings confirmed that SCP mediates the link between BDDSC and firm sustainable performance. Additionally, firm age moderates the association between BDDSC and SCP as well as between SCP and firm sustainable performance.Research limitations/implicationsThe role of SCP and firm age between BDDSC and sustainable performance have been examined in the context of MSMEs in Delhi-NCR and thereby limit the generalization of results to other industries and country contexts.Originality/valueThe present study adds to the existing literature via recognizing the blackbox using SCP and firm age to comprehend BDDSC and firm sustainable performance relationship.

Sign in / Sign up

Export Citation Format

Share Document