scholarly journals Review article: controversy in the therapy of gastro-oesophageal reflux disease-long-term proton pump inhibition or laparoscopic anti-reflux surgery?

1997 ◽  
Vol 11 (2) ◽  
pp. 249-260 ◽  
Author(s):  
S. J. WALKER ◽  
S. T. BAXTER ◽  
A. I. MORRIS ◽  
R. SUTTON
Keyword(s):  
Proton Pump ◽  
Reflux Disease ◽  
Review Article ◽  
Oesophageal Reflux ◽  
Oesophageal Reflux Disease ◽  
Proton Pump Inhibition

scholarly journals Side effects of drug treatments for gastro-oesophageal reflux disease: current controversies

2020 ◽  
pp. flgastro-2019-101386
Author(s):  
Anjan Dhar ◽  
Frances Maw ◽  
Helen Jane Dallal ◽  
Stephen Attwood
Keyword(s):  
Side Effects ◽  
Adverse Effects ◽  
Clinical Significance ◽  
Proton Pump ◽  
Reflux Disease ◽  
Critical Review ◽  
Oesophageal Reflux ◽  
Oesophageal Reflux Disease ◽  
Drug Treatments

The two main drugs used in the treatment of gastro-oesophageal reflux disease are proton pump inhibitors and histamine-2 receptor antagonists and both these agents have been implicated in a number of adverse effects, leading to considerable controversies related to their long-term use. This paper is aimed at a critical review of the published literature and the clinical significance of these reported side effects, most of which are associations rather than causal.

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