Pemphigus foliaceus and oral lichen planus in a patient with systemic lupus erythematosus and thymoma

1998 ◽  
Vol 23 (4) ◽  
pp. 181-184 ◽  
Author(s):  
NG ◽  
NG ◽  
CHNG
2018 ◽  
Vol 12 (1) ◽  
pp. 873-883 ◽  
Author(s):  
Parichehr Zarean ◽  
Paridokht Zarean ◽  
Negar Kanounisabet ◽  
Ahmad Moghareabed ◽  
Mansour Rismanchian ◽  
...  

Objective: Dental implantations are widely used for oral rehabilitation of edentulous patients. Despite high success rate, there are some risk factors that have been associated with failures. Oral mucocutaneous diseases are one of these risk factors for implant insertion due to the immunosuppressive therapy. There are limited studies that have dealt with the subject of dental implantology in oral mucosal disorders mainly with patients with oral lichenplanus, pemphigoid, pemphigus vulgaris, and systemic lupus erythematosus. In order to assess the result of implantations in such patients, we have reviewed the studies. Materials and Methods: We searched PubMed, Science Direct, and Cochrane databases for articles published from Jan 2000 to Dec 2017, using key search word “dental implants”, “oral lichen planus”, “pemphigoid”, “pemphigus vulgaris” and ”systemic lupus erythematosus”. Results: The random effects analysis result shows overall failure rates of 22% in patients with oral lichen planus. A systematic review revealed some failures that are not definitely related to these diseases. Conclusion: Due to the lack of adequate studies, a meta-analysis was only possible for oral lichen planus. Presently, there is no definite guideline regarding the placement of implant in patients suffering from mucocutaneous diseases; nevertheless, we should always consider that these patients are specific cases and need more attention in the first step of treatment and follow-ups. So there is a need to further clinical studies in order to evaluate more risk factors accurately and make a definitive conclusion.


2008 ◽  
Vol 35 (5) ◽  
pp. 306-307 ◽  
Author(s):  
Takashi KOBAYASHI ◽  
Atsushi HATAMOCHI ◽  
Noriaki KAMADA ◽  
Hiroyuki MATSUE ◽  
Hiroshi SHINKAI

1982 ◽  
Vol 7 (4) ◽  
pp. 478-483 ◽  
Author(s):  
A. Razzaque Ahmed ◽  
Patricia Schreiber ◽  
William Abramovits ◽  
Mark Ostreicher ◽  
Nicholas J. Lowe

2016 ◽  
Vol 58 (3) ◽  
pp. e120-e122 ◽  
Author(s):  
Soichiro Sawamura ◽  
Ikko Kajihara ◽  
Katsunari Makino ◽  
Takamitsu Makino ◽  
Satoshi Fukushima ◽  
...  

2021 ◽  
Vol 8 ◽  
Author(s):  
Yi Liu ◽  
Xuelei Liang ◽  
Haixuan Wu ◽  
Fenglin Zhuo

Introduction: Lichen planus/lupus erythematosus overlap syndrome is rarely seen in the clinic and has the characteristic clinical manifestations, histopathology, and immunopathology of lichen planus (LP) and lupus erythematosus (LE). This is the first reported case of bullous lichen planus (BLP)/systemic lupus erythematosus (SLE) overlap syndrome with hair loss as the first symptom.Case Presentation: A 48-year-old female presented with alopecia for half a year, and skin lesions accompanied by itching on her face, trunk, and limbs for 3 months. She had a history suggestive of photosensitivity. Laboratory tests and histopathology were performed for diagnosis. Histopathologic features of the upper arm and back of the hand were consistent with BLP, whereas the scalp lesion indicated LE. Laboratory examination indicated positive for antinuclear antibody (ANA) (1:160), leukopenia, increased urinary protein, decreased C3/C4, and normal BP180. The patient was given glucocorticoid combined with acitretin and immunosuppressive therapy after a definite diagnosis of BLP/SLE overlap syndrome. The lesions of the patient disappeared and some hair had regrown during the two years of follow-up.Conclusion: This is the first reported case of BLP/SLE overlap syndrome which responded well to glucocorticoids, retinoids, and immunosuppressive drugs. Multiple biopsies from characteristic lesions will guide doctors to avoid misdiagnoses and delayed treatment.


2016 ◽  
Vol 2 (3) ◽  
pp. 147
Author(s):  
Indah Suasani Wahyuni ◽  
Tenny Setiana Dewi ◽  
Erna Herawati ◽  
Dewi Zakiawati

Oral lesion’s profi le in autoimmune disease. Oral lesions are commonly found in patients with autoimmune diseases as manifestations of the disease or a side effect of the treatment. Oral lesions must be handled properly to prevent secondary infection, relieve pain and improve the patient’s quality of life. The aim of this study is to describe oral lesions profile in patients with autoimmune diseases, including clinical characteristics and location of oral lesions as well as the distribution of age and sex of the patient. The methods were retrospective observation by describing the secondary data from patients with autoimmune handled by Oral Medicine Specialist, Faculty of Dentistry, University of Padjadjaran in dr. Hasan Sadikin Hospital Dental Clinic. Patient files from August 2010 untill August 2014 (n = 66) were used, with the most often diagnosis were Systemic Lupus erythematosus (SLE), Oral lichen planus (OLP) and Pemphigus vulgaris (PV). It is revealed that, the age of patients varied between 9 to 68 years old and there was predominance of female patients. Patients diagnosed with SLE were 26 (39.4%), 12 patients with OLP (18.2%) and 28 patients with PV (42.4%). Based on the clinical feature, the most commonly found type of oral lesion was erosion (n=52/78,8%), while the most commonly predilection was in the buccal mucosa (n = 46/69,7%). In conclusion, intra-oral examination should be used as a routine procedure in the comprehensive management of patients with autoimmune diseases. Dentist have a professional role in the diagnosis of oral lesions and provide appropriate therapy in order to improve the quality of life of patients with autoimmune diseases.ABSTRAKLesi oral biasa ditemukan pada penderita penyakit autoimun sebagai manifestasi penyakit atau efek samping pengobatan kortikosteroid jangka panjang. Lesi oral harus ditangani dengan baik untuk mencegah terjadinya infeksi sekunder, mengatasi rasa sakit dan meningkatkan kualitas hidup penderita. Pengumpulan data gambaran profil lesi oral penderita penyakit autoimun, meliputi karakteristik klinis dan lokasi lesi oral serta distribusi usia dan jenis kelamin penderita belum pernah dilakukan. Metode yang digunakan adalah non eksperimen, retrospektif dan deskripsi data sekunder penderita autoimun yang ditangani oleh bagian Ilmu Penyakit Mulut FKG Universitas Padjadjaran di SMF Gigi dan Mulut RS dr. Hasan Sadikin Bandung. Data pasien yang dipergunakan antara bulan Agustus 2010 sampai Agustus 2014 (n=66), dengan diagnosis penyakit autoimun yang paling sering adalah Sistemic Lupus Erythematous (SLE), Oral Lichen Planus  (OLP) dan Pemphigus Vulgaris (PV). Semua pasien memberikan persetujuan pada saat dilakukan pemeriksaan dan  pengumpulan data melalui informed consent. Hasil penelitian ini menunjukkan usia penderita bervariasi antara 9 hingga 68 tahun dan jumlah penderita wanita lebih banyak daripada pria. Penderita yang didiagnosis SLE 26 orang (39,4%), OLP 12 orang (18,2%) dan PV 28 orang (42,4%). Berdasarkan gambaran klinisnya jenis lesi oral yang banyak ditemukan adalah erosi (n = 52/ 78,8%) dan berdasarkan lokasi lesi oral banyak ditemukan pada mukosa bukal (n = 46/69,7% penderita). Kesimpulannya, pemeriksaan intra oral disarankan menjadi prosedur rutin dalam tatalaksana komprehensif penderita penyakit autoimun. Dokter gigi diharapkan dapat berperan dalam mendiagnosis lesi oral dan memberikan terapi yang tepat sehingga dapat meningkatkan kualitas hidup penderita penyakit autoimun. 


Author(s):  
Y. T. KONTTINEN ◽  
M. MALMSTRÖM ◽  
S. REITAMO ◽  
E. TOLVANEN ◽  
A. SEPPÄ ◽  
...  

2016 ◽  
Vol 5 (1) ◽  
pp. 34-39 ◽  
Author(s):  
Helen Mcparland

Many red and white lesions of the mouth are clinically indistinguishable from those of oral lichen planus (OLP). These lesions, often referred to as oral lichenoid lesions (OLL), can occur as a result of contact sensitivity (lichenoid contact reactions), drug reactions or as part of chronic graft versus host disease (GVHD). Oral lesions in discoid lupus erythematosus (DLE) and systemic lupus erythematosus (SLE) can also have a similar clinical appearance to OLP. Distinguishing oral lichen planus from oral lichenoid lesions, lupus lesions, or other red and white lesions of the mouth can be difficult (even impossible) but it is important, for optimal management of each condition. All patients with red and white pathological lesions should be referred to an oral medicine or a local oral or maxillofacial surgery department, where a biopsy and other investigations can help to establish a diagnosis, and appropriate treatment and monitoring can be commenced. Dentists and other members of the dental team, such as hygienists and dental therapists, should also equip themselves with the knowledge to be able to explain different pathologies of the mouth to their patients and discuss risk factors.


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