scholarly journals A set of recombinant antigens from Echinococcus granulosus with potential for use in the immunodiagnosis of human cystic hydatid disease

2003 ◽  
Vol 132 (2) ◽  
pp. 309-315 ◽  
Author(s):  
V. G. VIRGINIO ◽  
A. HERNÁNDEZ ◽  
M. B. ROTT ◽  
K. M. MONTEIRO ◽  
A. F. ZANDONAI ◽  
...  
Keyword(s):  
Echinococcus Granulosus ◽  
Hydatid Disease ◽  
Cystic Hydatid Disease ◽  
Recombinant Antigens ◽  
Cystic Hydatid

Cystic hydatid disease (Echinococcus granulosus)

2020 ◽  
pp. 1529-1533
Author(s):  
Pedro L. Moro ◽  
Hector H. Garcia ◽  
Armando E. Gonzalez
Keyword(s):  
Echinococcus Granulosus ◽  
Hydatid Disease ◽  
Imaging Techniques ◽  
Clinical Manifestations ◽  
Public Health Problem ◽  
Major Public Health Problem ◽  
Cystic Hydatid Disease ◽  
Control Programmes ◽  
Domestic Livestock ◽  
Cystic Hydatid

Cystic hydatid disease, caused by Echinococcus granulosus, is a zoonotic disease principally transmitted between dogs and domestic livestock, particularly sheep. Humans are infected when they ingest tapeworm eggs, with disease occurring in most parts of the world where sheep are raised and dogs are used to herd livestock. The most common clinical manifestations are cysts in the liver (typically presenting with hepatomegaly) and/or lung (presenting with cough, haemoptysis, and dyspnoea). Diagnosis is usually made on the basis of serological tests in combination with imaging techniques. Treatment options include surgery, chemotherapy with anthelminthic agents, or—for liver cysts—PAIR (puncture–aspiration–injection–reaspiration). Echinococcosis is a major public health problem in several countries. Control programmes have been aimed at educating dog owners to prevent their animals from having access to infected offal. Vaccines against sheep hydatidosis and the dog tapeworm stage are promising alternatives.

Cystic hydatid disease (Echinococcus granulosus)

2010 ◽  
pp. 1185-1188
Author(s):  
Armando E. Gonzalez ◽  
Pedro L. Moro ◽  
Hector H. Garcia
Keyword(s):  
Echinococcus Granulosus ◽  
Hydatid Disease ◽  
Cystic Hydatid Disease ◽  
Cystic Hydatid

scholarly journals Oxfendazole Treatment for Cystic Hydatid Disease in Naturally Infected Animals

1998 ◽  
Vol 42 (3) ◽  
pp. 601-605 ◽  
Author(s):  
Ronald E. Blanton ◽  
Timothy M. Wachira ◽  
Eberhard E. Zeyhle ◽  
Ernest M. Njoroge ◽  
Japheth K. Magambo ◽  
...  
Keyword(s):  
Hydatid Disease ◽  
Cyst Wall ◽  
Inflammatory Cells ◽  
Chemotherapeutic Agents ◽  
Postmortem Examination ◽  
Cystic Hydatid Disease ◽  
Adventitial Layer ◽  
Cystic Hydatid

ABSTRACT Few chemotherapeutic agents are available for the medical management of hydatid disease caused by the parasite Echinococcus granulosus. In order to test the potential of oxfendazole for the treatment of infection with this parasite, nine infected goats and four sheep were given oxfendazole twice weekly at a dose of 30 mg/kg of body weight for 4 weeks and monitored by ultrasound for an additional 4 weeks. Efficacy was finally evaluated by postmortem examination, including determination of protoscolex viability and cyst wall histology. In treated animals, protoscolices were dead or absent in 97% of cysts from oxfendazole-treated animals compared to 28% of cysts from untreated control animals. On postmortem examination, 53% of cysts from treated animals were found to be grossly degenerate. A sample of those cysts that appeared potentially viable all demonstrated evidence of severe damage to the cyst wall. By light microscopy, cysts showed severe disorganization of the adventitial layer with invasion of inflammatory cells and in some cases frank necrosis with no apparent adventitial layer. The follow-up period for assessment of the drug’s ability to cause complete degeneration and resorption of cysts was relatively short. This study, however, indicates that oxfendazole is at least as effective as and is easier to administer than albendazole for the treatment of hydatid disease.

Cystic Hydatid Disease: Current Trends in Diagnosis and Management

Surgery Today ◽  
2004 ◽  
Vol 34 (12) ◽  
pp. 987-996 ◽  
Author(s):  
Iskender Sayek ◽  
M. Bulent Tirnaksiz ◽  
Riza Dogan
Keyword(s):  
Hydatid Disease ◽  
Cystic Hydatid Disease ◽  
Diagnosis And Management ◽  
Current Trends ◽  
Cystic Hydatid
Sign in / Sign up

Export Citation Format

Share Document