scholarly journals Effects of Aging on the Interaction Between Glutamate, Dopamine, and GABA in Striatum and Nucleus Accumbens of the Awake Rat

2002 ◽  
Vol 73 (5) ◽  
pp. 2063-2072
2004 ◽  
Vol 36 (3) ◽  
pp. 177-185 ◽  
Author(s):  
Tamara R. Castañeda ◽  
Blanca Marquez Prado ◽  
David Prieto ◽  
Francisco Mora

2009 ◽  
Vol 587 (8) ◽  
pp. 1695-1704 ◽  
Author(s):  
John A. Wolf ◽  
Leif H. Finkel ◽  
Diego Contreras

Author(s):  
Ke-Wei Huang ◽  
Yan Zhao

AbstractObjectiveTo investigate the effects of aging and anoxia on the nucleus accumbens.MethodsThe number of neurons in nucleus accumbens and caudate neucleus in 35 patients over 65 and 35 under 65 years, all without neurological or psychiatric diseases were counted.ResultsThere was no statistically significant difference between the number of neurons in the accumbens in the two groups, but there was a decrease in the number of neurons in the elderly group. There was no reduction in volume of the neuronal nucleoli of the accumbens measured in 12 elderly patients compared to controls. These data suggest a sparing of the accumbens from changes associated with aging. There was relative preservation of the nucleus accumbens in 3 patients with anoxic encephalopathy.ConclusionsThese results show that accumbens was resistant to both aging and anoxia, the mechanism of which is discussed.


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