scholarly journals Apa I polymorphism in the vitamin D receptor gene may affect the parathyroid response in Japanese with end-stage renal disease

1998 ◽  
Vol 53 (2) ◽  
pp. 454-458 ◽  
Author(s):  
Keitaro Yokoyama ◽  
Takashi Shigematsu ◽  
Toshihiko Tsukada ◽  
Yousuke Ogura ◽  
Fumi Takemoto ◽  
...  
Keyword(s):  
Vitamin D ◽  
Renal Disease ◽  
Vitamin D Receptor ◽  
End Stage Renal Disease ◽  
Receptor Gene ◽  
Vitamin D Receptor Gene ◽  
Stage Renal Disease ◽  
End Stage

scholarly journals Vitamin D receptor genetic variants among patients with end-stage renal disease

Renal Failure ◽  
2010 ◽  
Vol 32 (8) ◽  
pp. 969-977 ◽  
Author(s):  
Gaurav Tripathi ◽  
Richa Sharma ◽  
Raj K. Sharma ◽  
Sushil Kumar Gupta ◽  
Satya Narayan Sankhwar ◽  
...  
Keyword(s):  
Vitamin D ◽  
Renal Disease ◽  
Vitamin D Receptor ◽  
Genetic Variants ◽  
End Stage Renal Disease ◽  
Stage Renal Disease ◽  
End Stage

scholarly journals Levels of vitamin D receptor and CYP24A1 in patients with end-stage renal disease

2016 ◽  
Vol 16 (2) ◽  
pp. 462 ◽  
Author(s):  
Jia-Jun Ye ◽  
Tian-Biao Zhou ◽  
Yun-Fang Zhang ◽  
Qi Wang ◽  
Yan-Yan Su ◽  
...  
Keyword(s):  
Vitamin D ◽  
Renal Disease ◽  
Vitamin D Receptor ◽  
End Stage Renal Disease ◽  
Stage Renal Disease ◽  
End Stage

scholarly journals Association of vitamin D receptor TaqI and ApaI genetic polymorphisms with nephrolithiasis and end stage renal disease: a meta-analysis

2019 ◽  
Vol 20 (1) ◽  
Author(s):  
Tajamul Hussain ◽  
Shaik M. Naushad ◽  
Anwar Ahmed ◽  
Salman Alamery ◽  
Arif A. Mohammed ◽  
...  
Keyword(s):  
Vitamin D ◽  
Renal Disease ◽  
Vitamin D Receptor ◽  
End Stage Renal Disease ◽  
Meta Analysis ◽  
Fixed Effect ◽  
Renal Diseases ◽  
Vdr Gene ◽  
Stage Renal Disease ◽  
End Stage

Abstract Background The deficiency of vitamin D receptor (VDR) or its ligand, vitamin D3, is linked to the development of renal diseases. The TaqI (rs731236) and ApaI (rs7975232) polymorphisms of VDR gene are widely studied for their association with renal disease risk. However, studies have largely been ambiguous. Methods Meta-analysis was carried out to clarify the association of TaqI (2777 cases and 3522 controls) and ApaI (2440 cases and 3279 controls) polymorphisms with nephrolithiasis (NL), diabetic nephropathy (DN) and end stage renal disease (ESRD). Results The VDR TaqI C-allele under allele contrast was significantly associated with ESRD in both fixed effect and random effect models, and ApaI C-allele with ESRD only under fixed effect model. Cochrane Q-test showed no evidence of heterogeneity for TaqI polymorphism and a significant heterogeneity for Apa I polymorphism. No publication bias was observed for both the polymorphisms. Conclusions The present meta-analysis identifies TaqI and ApaI polymorphisms of VDR gene as risk factors for renal diseases.

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