This paper analyzes the characteristics of Integrated Fire Control, one of the combat models of the Network-Centric war, and presents the hierarchical control structure of different combat units according to their corresponding functions. The Multi-Agent System structure is also presented, and different Agent models are established according to roles they play in the system. This paper adopts the acquaintance coalition theory and the Contract Net Protocol to realize the negotiation among different hierarchical Agents. The acquaintance coalition has the advantage of reducing the range of bids and costs of communications. The Contract Net Protocol is employed in the three-layer Multi-Agent System, and is an effective negotiation to allocate the missile intercept tasks in real-time and dynamic environment.