Ecotoxicants Content of Sanguisorba officinalis L., Growing on Mining Disturbed Lands of Kemerovo Region

Ecotoxicant content – heavy metals and radionuclides in embryonic soils and herbal medicinal products of Sanguisorba officinalis L. of the rose family (Rosaceae) in the circumstance of technogenicallydisturbed lands was analyzed, in example of the rock waste disposal areaof the Kedrovsky coal pit in Kemerovo region. It was experimentally proved that the embryonic soils of the coal dump is characterized by largeelemental variation. Analysis revealed that the raw materials of Sanguisorba officinalis L. more accumulates such metals as Fe(61, 95mg/kg), Mn (33, 46 mg/kg), Zn (17, 53 mg/kg) and Cu (12, 35mg/kg), which are related to biophilic metals. Technogenical group ofelements – Pb, Cd, Cr, Ni, Co, are with in 0,04 … 1,52 mg/kg. It was alsoexperimentally proved that the main share in overall radioactivity ofembryonic soils and rhizome and roots of greaterburnet falls to naturalradionuclides, especially K-40. The share of Cs-137 and Sr-90 are about7% in embryonic soils and 85 in rhizome and roots of burnet. Ecological hygienic assessment of Sanguisorba officinalis L. herbal medicinal products has shown the MPC no-exceedance of heavy metals and radionuclides, provided for the plant based BAA.

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Limits for the Content of Heavy Metals and Arsenic as a Means of Ensuring Safe Use of Herbal Medicinal Products

Safety and Risk of Pharmacotherapy ◽

10.30895/2312-7821-2021-9-2-61-68 ◽

2021 ◽

Vol 9 (2) ◽

pp. 61-68

Author(s):

M. S. Galenko ◽

I. V. Gravel ◽

N. Yu. Velts ◽

R. N. Alyautdin

Keyword(s):

Heavy Metals ◽

Human Body ◽

Toxic Elements ◽

Quantitative Methods ◽

Arsenic Content ◽

Medicinal Products ◽

Herbal Medicinal Products ◽

Herbal Medicinal ◽

Heavy Metals And Arsenic

Herbal medicinal products (HMPs) are widely used in medical practice due to their availability, ease of use, and relatively safe pharmacological proﬁle. However, medicinal plants are capable of accumulating heavy metals and arsenic which can have toxic eﬀect on the human body when found in HMPs. The aim of the study was to summarise and analyse requirements of the Russian and foreign pharmacopoeias for the limits of heavy metals and arsenic in HMPs. National and regional pharmacopoeias have limits for the content of the major toxic elements (lead, cadmium, mercury, chromium, and arsenic) in HMPs. The study showed that the Indian and Japanese pharmacopoeias include only semi-quantitative methods for determination of heavy metals and arsenic, while the Russian and Chinese pharmacopoeias allow for the use of both quantitative and semi-quantitative methods. It was demonstrated that the limits for heavy metals and arsenic are the same for herbal substances and HMPs. The development of consistent approaches to determination of heavy metals and arsenic content, a systematic transition to quantitative methods of analysis, and establishment of individual limits for toxic elements in diﬀerent HMP dosage forms, will make it possible to achieve the so-called consistent harmonisation, ensure reliable assessment of the content of heavy metals and arsenic, and minimize the risk of their entering human body with HMPs.

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Determination of heavy metals in Ayurvedic herbal preparations by atomic emission spectrometry

Terapevt (General Physician) ◽

10.33920/med-12-2101-11 ◽

2021 ◽

pp. 62-65

Author(s):

Margarita Dmitrievna Anikina ◽

Yuliya Eduardovna Generalova ◽

Irina Valerievna Gravel

Keyword(s):

Heavy Metals ◽

Atomic Emission ◽

Atomic Emission Spectrometry ◽

Emission Spectrometry ◽

Qualitative And Quantitative Analysis ◽

Medicinal Products ◽

Herbal Medicinal Products ◽

Qualitative And Quantitative ◽

Herbal Medicinal

The article presents the results of a qualitative and quantitative analysis of the content of heavy metals in herbal medicinal products used in Ayurveda.

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Identification of herbal products used by families in the campus of Darussalam Gontor University

Pharmacy Education ◽

10.46542/pe.2021.212.3135 ◽

2021 ◽

pp. 31-35

Author(s):

Amal Fadholah ◽

Solikah Ana Istikomah ◽

Cania Sofyan Islamanda ◽

Evi Rohana Ma’rufi Jannah

Keyword(s):

Raw Materials ◽

Rapid Assessment ◽

Product Safety ◽

Assessment Procedure ◽

Medicinal Products ◽

Herbal Products ◽

Herbal Medicinal Products ◽

Herbal Medicine Product ◽

Herbal Medicinal ◽

Medicine Product

Background: The development and the use of herbal medicinal products is increasing in Indonesia. Aim: To identify the safety of herbal medicine product used by families of Darussalam Gontor University (UNIDA) Gontor. Method: This research was conducted to identify herbal products that are used based on features, functions, and benefits. The method used was Rapid Assessment Procedure (RAP) with a qualitative approach. Results: The results showed there were 100 products used by 72 respondents. The level of product safety used based on raw materials was 96% and the efficacy claimed was 76%. The most type of product used was jamu (Indonesian indigenous traditional medicine) (94.7%). The range of understanding level of of respondents based on features and benefits was between good and very good. Conclusion: The use of herbal products by respondents can be viewed from the aspect of product safety levels based on raw materials (96%) and efficacy claims (76%). This was still classified as safe.

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