Fetal Surgery for Congenital Diaphragmatic Hernia: The North American Experience

2005 ◽  
Vol 29 (2) ◽  
pp. 104-111 ◽  
Author(s):  
Darrell L. Cass
Keyword(s):  
Congenital Diaphragmatic Hernia ◽  
Diaphragmatic Hernia ◽  
North American ◽  
Fetal Surgery ◽  
American Experience ◽  
The North

Origins and Evolution of the North American Stable Peace

2020 ◽  
Author(s):  
David G. Haglund
Keyword(s):  
International Relations ◽  
North American ◽  
Western Europe ◽  
Regional Security ◽  
Interstate Relations ◽  
American Experience ◽  
Back Seat ◽  
The North ◽  
Security Communities ◽  
Primary Focus

Interstate relations among the North American countries have been irenic for so long that the continent is often assumed to have little if anything to contribute to scholarly debates on peaceful change. In good measure, this can be attributed to the way in which discussions of peaceful change often become intertwined with a different kind of inquiry among international relations scholars, one focused upon the origins and denotative characteristics of “pluralistic security communities.” Given that it is generally (though not necessarily accurately) considered that such security communities first arose in Western Europe, it is not difficult to understand why the North American regional-security story so regularly takes an analytical back seat to what is considered to be the far more interesting European one. This article challenges the idea that there is little to learn from the North American experience, inter alia by stressing three leading theoretical clusters within which can be situated the scholarly corpus of works attempting to assess the causes of peaceful change on the continent. Although the primary focus is on the Canada–US relationship, the article includes a brief discussion of where Mexico might be said to fit in the regional-security order.

Right-sided congenital diaphragmatic hernia in a decade of fetal surgery

2014 ◽  
Vol 122 (7) ◽  
pp. 940-946 ◽  
Author(s):  
P DeKoninck ◽  
O Gomez ◽  
I Sandaite ◽  
J Richter ◽  
K Nawapun ◽  
...  
Keyword(s):  
Congenital Diaphragmatic Hernia ◽  
Diaphragmatic Hernia ◽  
Fetal Surgery

scholarly journals Fetoscopic abdominal decompression of congenital diaphragmatic hernia – preliminary results of a fetal sheep model

2014 ◽  
Author(s):  
Felipe Fromm ◽  
Katharina Wenke ◽  
Thomas Krebs ◽  
Michael Boettcher ◽  
Georg Eschenburg ◽  
...  
Keyword(s):  
Animal Model ◽  
Congenital Diaphragmatic Hernia ◽  
Diaphragmatic Hernia ◽  
Fetal Surgery ◽  
Amniotic Cavity ◽  
Sheep Model ◽  
Fetal Sheep ◽  
Tracheal Occlusion ◽  
Animal Trials ◽  
Abdominal Decompression

Background Severe congenital diaphragmatic hernia (CDH) is prenatally managed by fetoscopic tracheal occlusion (FETO) to improve lung growth and maturation. As FETO is not able to reduce the pressure onto the developing lungs originating from the intestine growing into the thoracic cavity, fetal abdominal decompression may alleviate this pressure effect by directing the growing intestine into the amniotic cavity away from the lungs. Therefore, aim of this study was to establish an animal model for fetoscopic abdominal decompression in fetal sheep with CDH. Methods CDH was created surgically on day 75 of 145 day gestation in eight fetuses. 2-3 weeks later, an opening was created in the fetal abdomen by fetoscopic surgery. The fetuses were retrieved by cesarean section at the end of pregnancy and evaluated. Results Five fetuses with CDH were treated with fetoscopic abdominal decompression. Three fetuses with CDH were taken as controls. One fetus was lost after creation of the CDH and two other after creation of the abdominal defect. Preliminary sterological results showed that the septal thickness of the experimental group was smaller than in the CDH group. Conclusion This study demonstrates the general feasibility of fetoscopic abdominal decompression for diaphragmatic hernia in our new animal model. Although not statistically significant, the lungs of treated fetuses were larger and heavier than those of untreated controls. Our findings support the hypothesis of palliative fetal surgery for severe CDH compared to tracheal occlusion. More controlled animal trials are needed.

scholarly journals Outcome of fetuses with congenital diaphragmatic hernia and associated intrafetal fluid effusions managed in the era of fetal surgery

2011 ◽  
Vol 39 (1) ◽  
pp. 50-55 ◽  
Author(s):  
T. Van Mieghem ◽  
R. Cruz-Martinez ◽  
K. Allegaert ◽  
P. Dekoninck ◽  
M. Castanon ◽  
...  
Keyword(s):  
Congenital Diaphragmatic Hernia ◽  
Diaphragmatic Hernia ◽  
Fetal Surgery
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