Facile Synthesis of Polysubstituted 2-Pyrones via TfOH-Mediated Ring Expansion of 2-Acylcyclopropane-1-Carboxylates

Synthesis ◽  
2021 ◽  
Author(s):  
Jiru Shao ◽  
Caiyun An ◽  
Sunewang Rixin Wang
Keyword(s):  
Cyclopropane Ring ◽  
Bond Cleavage ◽  
Ring Expansion ◽  
Facile Synthesis ◽  
Aryl Group ◽  
Pyrone Ring ◽  
Donor Acceptor ◽  
Facile Route

A facile route to polysubstituted 2-pyrones from readily available 2-acylcyclopropane-1-aryl-1-carboxylates mediated by TfOH is reported. The strongly donating 1-aryl group is important for directing the C-C bond cleavage of the donor-acceptor cyclopropane ring, which then leads to the formation of the 2-pyrone ring through lactonization.

Facile synthesis of organosilica-capped mesoporous silica nanocarriers with selective redox-triggered drug release properties for safe tumor chemotherapy

2019 ◽  
Vol 7 (5) ◽  
pp. 1825-1832 ◽  
Author(s):  
Luying Shen ◽  
Shan Pan ◽  
Dechao Niu ◽  
Jianping He ◽  
Xiaobo Jia ◽  
...  
Keyword(s):  
Drug Release ◽  
Mesoporous Silica ◽  
Facile Synthesis ◽  
Triggered Drug Release ◽  
Facile Route

We develop a facile route to synthesize organosilica-capped mesoporous silica nanocarriers for efficient and safe redox-triggered tumor chemotherapy.

Donor–Acceptor Cyclopropane Ring Opening with 6-Amino-1,3-dimethyluracil and Its Use in Pyrimido[4,5-b]azepines Synthesis

2021 ◽  
Author(s):  
Anna E. Vartanova ◽  
Irina I. Levina ◽  
Victor B. Rybakov ◽  
Olga A. Ivanova ◽  
Igor V. Trushkov
Keyword(s):  
Ring Opening ◽  
Cyclopropane Ring ◽  
Donor Acceptor

Facile synthesis and self-assembly of diazafluorenone-based p–n (donor–acceptor) organic semiconductors

Tetrahedron ◽  
2012 ◽  
Vol 68 (39) ◽  
pp. 8216-8221 ◽  
Author(s):  
Wei-Jie Li ◽  
Hai-Mei Wu ◽  
Yi-Bao Li ◽  
Chao-Peng Hu ◽  
Ming-Dong Yi ◽  
...  
Keyword(s):  
Organic Semiconductors ◽  
Self Assembly ◽  
Facile Synthesis ◽  
Donor Acceptor

scholarly journals A Vinyl Cyclopropane Ring Expansion and Iridium‐Catalyzed Hydrogen Borrowing Cascade

2020 ◽  
Vol 132 (28) ◽  
pp. 11435-11440
Author(s):  
Simon Wübbolt ◽  
Choon Boon Cheong ◽  
James R. Frost ◽  
Kirsten E. Christensen ◽  
Timothy J. Donohoe
Keyword(s):  
Cyclopropane Ring ◽  
Ring Expansion

Facile synthesis of polypyrrole@metal–organic framework core–shell nanocomposites for dual-mode imaging and synergistic chemo-photothermal therapy of cancer cells

2017 ◽  
Vol 5 (9) ◽  
pp. 1772-1778 ◽  
Author(s):  
Xiangjun Chen ◽  
Manjie Zhang ◽  
Shengnan Li ◽  
Lu Li ◽  
Lingyu Zhang ◽  
...  
Keyword(s):  
Magnetic Resonance ◽  
Cancer Cells ◽  
Photothermal Therapy ◽  
Photoacoustic Imaging ◽  
Metal Organic Framework ◽  
Core Shell ◽  
Dual Mode ◽  
Facile Synthesis ◽  
Metal Organic ◽  
Facile Route

A facile route was developed to fabricate PPy@MOF for dual-mode magnetic resonance/photoacoustic imaging and synergistic chemo-photothermal therapy.

Brønsted acid-catalyzed selective C–C bond cleavage of 1,3-diketones: a facile synthesis of 4(3H)-quinazolinones in aqueous ethyl lactate

RSC Advances ◽  
2015 ◽  
Vol 5 (104) ◽  
pp. 85646-85651 ◽  
Author(s):  
Guanshuo Shen ◽  
Haifeng Zhou ◽  
Peng Du ◽  
Sensheng Liu ◽  
Kun Zou ◽  
...  
Keyword(s):  
Bond Cleavage ◽  
Ethyl Lactate ◽  
Bronsted Acid ◽  
Brønsted Acid ◽  
Facile Synthesis ◽  
Brönsted Acid ◽  
Acid Catalyzed
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