Diagnostic Value of Bone SPECT/CT Using 99mTc-Methylene Diphosphonate in Patients with Unspecified Chest Wall Pain

2021 ◽  
Author(s):  
Soo Bin Park ◽  
Chae Hong Lim ◽  
Won Ho Chang ◽  
Jung Hwa Hwang ◽  
Ji Young Lee ◽  
...  
Keyword(s):  
Computed Tomography ◽  
Chest Wall ◽  
Bone Scan ◽  
Diagnostic Performance ◽  
Single Photon ◽  
Photon Emission ◽  
Older Age ◽  
Emission Computed Tomography ◽  
Age Group ◽  
Abnormal Finding

Abstract Purpose We investigated the diagnostic performance of single photon emission computed tomography (SPECT)/computed tomography (CT) as a combination of functional and anatomic imaging, in patients with unspecified chest wall pain. Methods Fifty-two patients with unspecified chest wall pain and no history of recent major traumatic events or cardiac disease were included. The number and location of radioactive chest wall lesions were evaluated on both planar images and SPECT/CT. The clinical diagnosis was made based on all of the clinical and imaging data and follow-up information. Results Chest wall diseases were diagnosed in 42 patients (80.8 %). SPECT/CT showed abnormal findings in 35 (67.3 %) patients with positive predictive value (PPV) of 97.1 %. SPECT/CT revealed 56 % more lesions than planar bone scan (P = 0.002) and most of the abnormal radioactive lesions (94.6 %) showed combined morphological changes on the matched CT component. When comparing between age subgroups (< 60 y vs. ≥ 60 y), the prevalence of chest wall disease and diagnosis rate of fracture was significantly higher in the older age group. On SPECT/CT, the older age group showed higher frequency of having abnormal finding (95.8 % vs. 42.9 %, P < 0.001) and significantly more lesions were detected (a total of 189 vs. 32, P = 0.003). Conclusion SPECT/CT showed good diagnostic performance and proved to have higher sensitivity, detecting 56 % more lesions than planar bone scan. A negative result could be helpful for excluding pathologic chest wall disease. SPECT/CT might be recommended for integration in to the diagnostic workup in patients with unspecified chest wall pain, especially in patients ≥ 60 y of age, considering the high disease prevalence and the high frequency of positive results.

scholarly journals INTRAOSSEOUS HAEMANGIOMAS ON HYBRID IMAGING: A PICTORIAL REVIEW

2016 ◽  
Vol 2 (2) ◽  
Author(s):  
Mairah Razi ◽  
Humayun Bashir ◽  
Saima Riaz ◽  
Zia S Faruqui
Keyword(s):  
Computed Tomography ◽  
Bone Scan ◽  
Single Photon ◽  
Photon Emission ◽  
Emission Computed Tomography ◽  
Single Photon Emission ◽  
Methylene Diphosphonate ◽  
Pictorial Review ◽  
Single Photon Emission Computed ◽  
Photon Emission Computed Tomography

Osseous haemangiomas are benign skeletal tumours, usually identi ed as incidental ndings on different imaging modalities. Bone scan is the most frequent radionuclide procedure performed as metastatic workup in patients with various malignancies. Not every hotspot on a staging bone scan is malignant. Haemangiomas with variable degree of radiotracer uptake on technetium-99m (Tc-99m) bone scintigraphy may be falsely labelled as metastases in background of known malignancy. The addition of single-photon emission computed tomography computed tomography (SPECT-CT) enhances the specificity of bone scan which allows accurate detection and anatomical localisation of scintigraphic findings. We present a case series as pictorial review of osseous haemangiomas identi ed on Tc-99m methylene diphosphonate SPECT CT at our department. Key words: Haemangioma, methylene diphosphonate, bone scan, single-photon emission computed tomography- computed tomography

Location of Sentinel Lymph Node in Cervical Carcinoma and Factors Associated With Unilateral Detection

2015 ◽  
Vol 25 (9) ◽  
pp. 1663-1668 ◽  
Author(s):  
Rekha Wuntakal ◽  
Andreas John Papadopoulos ◽  
Stephen Attard Montalto ◽  
Milica Perovic ◽  
Michael Coutts ◽  
...  
Keyword(s):  
Computed Tomography ◽  
Single Photon ◽  
Gamma Probe ◽  
Photon Emission ◽  
Pelvic Lymphadenectomy ◽  
Older Age ◽  
Emission Computed Tomography ◽  
Internal Iliac ◽  
Single Photon Emission Computed ◽  
Photon Emission Computed Tomography

ObjectiveThe aims of this study were to assess locality of the sentinel lymph node (SLN) in cervical carcinoma and examine factors affecting bilateral SLN detection.MethodsThis was a retrospective review of SLN data (anatomical location, count and laterality) in patients with early-stage cervical cancer (International Federation of Gynecology and Obstetrics stage IA1 with lymphovascular space invasion to stage IIA) using intraoperative gamma probe and blue dye. The preoperative single-photon emission computed tomography with computed tomography was used to detect laterality, number of the SLNs, and rare locations. Patients were treated between January 2005 to January 2015 at the West Kent Gynaecological Oncology Centre, Maidstone Hospital, Maidstone, United Kingdom.ResultsA total of 132 women were investigated. The most common SLN location was the external iliac (38.6%) followed by obturator (25.3%) and internal iliac (23.6%) regions. A small percentage was identified in presacral (1.4%) and para-aortic regions (0.7%). Older age (P= 0.01) and an elevated body mass index (P= 0.03) were associated with decreased SLN count by preoperative single-photon emission computed tomography with computed tomography, and only age affected SLN count by gamma probe (P= 0.01). Initial surgery, large loop excision of the transformation zone, or cone biopsy of the cervix had no effect on SLN count. There was no difference observed in bilateral detection with respect to surgical approach (open: n = 48/laparoscopic: n = 84). However, older age was independently associated with a decrease in bilateral SLN detection (P= 0.003). In these patients who underwent unilateral full pelvic lymphadenectomy, all the nonsentinel nodes were negative.ConclusionsThe majority of SLNs were located in the external iliac, obturator, and internal iliac regions. Both older age and an elevated body mass index were associated with a reduced SLN count. Unilateral detection of SLN was independently associated with older age, which may be due to sclerosis in the lymphatic vessels or reduced perfusion in the pelvis in these women. If no SLN is detected on one side, the consensus is to perform a full pelvic lymphadenectomy on that side of the pelvis.

scholarly journals Hybrid Magnetic Resonance Imaging with Single Photon Emission Computed Tomography/Computed Tomography Bone Scan for Diagnosis Of Avascular Necrosis of Femoral Head

2021 ◽  
Vol 11 ◽  
pp. 2
Author(s):  
Fung Him Ng ◽  
Terence Kin Bong Lai ◽  
Sun Yu Lam ◽  
Nin Yuan Pan ◽  
Wing Hang Luk
Keyword(s):  
Magnetic Resonance Imaging ◽  
Computed Tomography ◽  
Bone Scan ◽  
Single Photon ◽  
Photon Emission ◽  
Emission Computed Tomography ◽  
Resonance Imaging ◽  
Single Photon Emission ◽  
Single Photon Emission Computed ◽  
Photon Emission Computed Tomography

Magnetic resonance imaging (MRI) is a commonly used imaging modality to detect early avascular necrosis (AVN). When MRI is inconclusive, bone scan is helpful in detecting AVN during early phase of the disease. As newer nuclear medicine equipment, such as single photon emission computed tomography/computed tomography (SPECT/CT) and positron emission tomography, are emerging in medical science, the role of these imaging modalities in AVN of femoral head is re-evaluated.

Evaluation of the SPECT/CT Method in the Diagnosis of Ochronosis. Clinical Case

2020 ◽  
Vol 65 (2) ◽  
pp. 82-86
Author(s):  
A. Ryzhkov ◽  
A. Krylov ◽  
A. Bludov ◽  
A. Kuzin ◽  
S. Kaspshik ◽  
...  
Keyword(s):  
Computed Tomography ◽  
Musculoskeletal System ◽  
Bone Scan ◽  
Clinical Case ◽  
Structural Changes ◽  
Single Photon ◽  
Mineral Metabolism ◽  
Photon Emission ◽  
Emission Computed Tomography ◽  
Metabolism Disorder

Purpose: Is to demonstrate functional and structural changes in the musculoskeletal system of the patient with ochronosis using bone scan and hybrid imaging consisting of single-photon emission computed tomography (SPECT) and X-ray transmission computed tomography (CT) scan (SPECT/CT). Material and methods: A clinical case report of patient with ochronosis, examined with bone scan and SPECT/CT. Results: In this article we show a clinical case with the picture of mineral metabolism disorder and severe degenerative changes of musculoskeletal system in patient with ochronosis (a genetically determined disease), caused by metabolic disorders of homogentisic acid. We used hybrid SPECT/CT method for evaluation of this disease. Conclusion: SPECT/CT method demonstrated structural and metabolic changes. This method allowed us to reveal the specific changes in cases of ochronosis, but also it shows the possibility of using radionuclide methods in solving non-standard situations, while this method has not previously been applied.

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