scholarly journals Hybrid argon plasma coagulation-assisted endoscopic mucosal resection for large sessile colon polyps to reduce local recurrence: a prospective pilot study

Endoscopy ◽  
2021 ◽  
Author(s):  
Victoria L. Motz ◽  
Courtney Lester ◽  
Matthew T. Moyer ◽  
Jennifer L. Maranki ◽  
John M. Levenick
Keyword(s):  
Pilot Study ◽  
Local Recurrence ◽  
Endoscopic Mucosal Resection ◽  
Recurrence Rate ◽  
Argon Plasma Coagulation ◽  
Argon Plasma ◽  
Colon Polyps ◽  
Plasma Coagulation ◽  
Prospective Pilot Study

Abstract Background Endoscopic mucosal resection (EMR) of large, sessile colon polyps often results in incomplete resection with subsequent recurrence. The aim of this prospective pilot study was to evaluate the efficacy and safety of a novel technique, hybrid argon plasma coagulation-assisted EMR (hAPC-EMR), to remove large, sessile polyps. Methods 40 eligible patients underwent hAPC-EMR for the removal of one or more nonpedunculated colon polyps ≥ 20 mm. Participants were contacted 30 days post-procedure to assess for adverse events and were recommended to return for a surveillance colonoscopy at 6 months to assess for local recurrence. Results At the time writing, 32 patients with 35 polyps (median size 27 mm; interquartile range 14.5 mm) resected by hAPC-EMR had undergone the 6-month follow-up colonoscopy. Recurrence rate was 0 % (95 % confidence interval [CI] 0–0) at follow-up. Post-polypectomy bleeding was experienced by three patients (7.5 %; 95 %CI 0.00–0.15), and no patients developed post-polypectomy syndrome. Conclusion These preliminary results showed 0 % local recurrence rate at 6 months and demonstrated the safety profile of hAPC-EMR. A large, randomized, controlled trial is required to confirm these results.

scholarly journals Burn the Base to Get the Polyp Erased: A Novel Technique to Reduce Post-EMR Recurrence

2021 ◽  
Author(s):  
John Maynard Levenick ◽  
Adnrew J Groff ◽  
Carl Manzo ◽  
Courtney Lester ◽  
Jennifer L Maranki
Keyword(s):  
Local Recurrence ◽  
Endoscopic Mucosal Resection ◽  
Recurrence Rate ◽  
Focal Therapy ◽  
Standard Group ◽  
Colon Polyps ◽  
Recurrence Rates ◽  
Novel Technique ◽  
Standard Techniques

Abstract Background and Aims: Endoscopic mucosal resection (EMR) has become the standard for removing large colon polyps but has a 10-30% recurrence rate using standard techniques. Data shows improved recurrence rates with focal therapy of the edge of the resection base using cautery. We examine a novel technique, hybrid APC assisted EMR, which treats both the edge and the base with cautery to assess its effect on local recurrence. Methods: We reviewed all EMRs of polyps >2cm by a single endoscopist with six month follow-up from May 2018-November 2019 using both standard EMR as well as hybrid APC assisted EMR to assess local recurrence as well complications. Results: 48 patients with 59 polyps removed by EMR had full six month follow up with a mean age of 66.1 years of age, 45% were female. 30 polyps were removed by hybrid APC assisted EMR and 29 removed with standard EMR. Overall, 0 (0%) polyps in the h-APC arm had local recurrence while 6 (20.7%) in the standard group had histological proven local recurrence (p=0.01). Post-resection bleeding occurred in 6 patients, 2 in the hAPC arm and 4 in the standard arm (p=0.41). Conclusions: Hybrid APC assisted EMR was superior to conventional EMR for local recurrence after removal of large colon polyps and trended towards a less post-EMR bleeds.

Endoscopic mucosal resection for recurrent gastric antral vascular ectasia

VASA ◽  
2008 ◽  
Vol 37 (3) ◽  
pp. 289-292 ◽  
Author(s):  
Katsinelos ◽  
Chatzimavroudis ◽  
Katsinelos ◽  
Panagiotopoulou ◽  
Kotakidou ◽  
...  
Keyword(s):  
Endoscopic Mucosal Resection ◽  
Argon Plasma Coagulation ◽  
Argon Plasma ◽  
Deficiency Anemia ◽  
Gastric Antral Vascular Ectasia ◽  
Therapeutic Approaches ◽  
Plasma Coagulation ◽  
Vascular Ectasia ◽  
Mucosal Resection ◽  
First Case

Gastric antral vascular ectasia (GAVE) is an overt or occult source of gastrointestinal bleeding. Despite several therapeutic approaches have been successfully tested for preventing chronic bleeding, some patients present recurrence of GAVE lesions. To the best of our knowledge, we report the first case, of a 86-year-old woman who presented severe iron-deficiency anemia due to GAVE and showed recurrence of GAVE lesion despite the intensive argon plasma coagulation treatment. We performed endoscopic mucosal resection of bleeding GAVE with resolution of anemia.

scholarly journals Endoscopic treatment of gastric and duodenal angiodysplasias by elastic rings ligation

2012 ◽  
Vol 140 (3-4) ◽  
pp. 168-172
Author(s):  
Sasa Grgov ◽  
Perica Stamenkovic ◽  
Dejan Janjic
Keyword(s):  
Endoscopic Treatment ◽  
Argon Plasma Coagulation ◽  
Argon Plasma ◽  
Active Bleeding ◽  
Average Period ◽  
Efficacy And Safety ◽  
Plasma Coagulation ◽  
Heater Probe ◽  
Endoscopic Ligation

Introduction. The most frequently applied methods of endoscopic treatment of angiodysplasias, such as argon plasma coagulation, multipolar coagulation and heater probe, proved to be effective with certain shortcomings and the possibility of complications. There are very scarce data in the literature about the treatment of angiodysplasias with endoscopic ligature. Objective. The aim of the study was to examine the efficacy and safety of endoscopic treatment of gastric and duodenal angiodysplasias by ligation with elastic rings. Methods. In 12 patients (10 male and 2 female, mean age 65.9 years) the endoscopic ligation of gastric and duodenal angiodysplasias was applied. Eight patients (66.6%) had solitary angiodysplasias in the stomach, two patients (16.6%) had solitary angiodysplasias in the descending part of the duodenum and two patients (16.6%) had multiple angiodysplasias in the stomach and duodenum. Two patients (16.6%) had active bleeding from angiodysplasias, while 10 patients (83.3%) had recent bleeding. We used the Cook Endoscopy system with 4 or 6 elastic rings for endoscopic ligation of angiodysplasias. Patients were under follow-up after 2-3 days, 30 days and then every 6 months following the endoscopic ligation of angiodysplasias. Results. Active bleeding from angiodysplasias was stopped in two patients (100%) by endoscopic ligation with elastic rings. The average number of applied ligation sessions in our 12 patients was 1.6, with an average of 1.8 ligatures per session. There were no complications after ligation of angiodysplasias. Recurrence of bleeding occurred in one patient (8.3%) with multiple gastric and duodenal angiodysplasias. The average period of follow-up of patients was 22.8?17.6 months. Conclusion. Endoscopic ligation with elastic rings can be effective and safe for treatment especially of solitary gastric and duodenal angiodysplasias.

Mo1201 EFFICACY, TOLERANCE, AND SAFETY OF HYBRID ARGON PLASMA COAGULATION FOR THE TREATMENT OF BARRETT'S ESOPHAGUS: A U.S. PILOT STUDY

2019 ◽  
Vol 89 (6) ◽  
pp. AB461
Author(s):  
Toshitaka Shimizu ◽  
Jason B. Samarasena ◽  
Kyle J. Fortinsky ◽  
Rintaro Hashimoto ◽  
Allen R. Yu ◽  
...  
Keyword(s):  
Pilot Study ◽  
Barrett’S Esophagus ◽  
Barrett's Esophagus ◽  
Argon Plasma Coagulation ◽  
Argon Plasma ◽  
Plasma Coagulation

4-year follow-up of patients with barretts epithelium after ablation with argon plasma coagulation

2003 ◽  
Vol 124 (4) ◽  
pp. A634
Author(s):  
Ahmed Madisch ◽  
Stephan Miehlke ◽  
Ekkehard Bayerdoerffer ◽  
Michael Vieth ◽  
Anke Sievert ◽  
...  
Keyword(s):  
Argon Plasma Coagulation ◽  
Argon Plasma ◽  
Plasma Coagulation
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