5 Surgical Approach to Pediatric Bone and Soft-Tissue Tumors of the Lower Extremity

Background Time-resolved angiography with stochastic trajectories (TWIST) sequence makes considerable progress in temporal and spatial resolution, which presents high potential in evaluation of vascular diseases. Purpose To assess magnetic resonance imaging (MRI) using TWIST MR angiography (MRA) sequence in the assessment of vascular invasion for bone and soft-tissue tumors in comparison to computed tomography angiography (CTA) as the reference standard. Material and Methods Thirty-three patients with lower extremity musculoskeletal tumors were imaged with conventional MR and TWIST MRA. CTA was performed 48 h later. The signal-to-noise ratio (SNR) and contrast-to-noise ratio (CNR) of the femoral artery were calculated. Vascular invasion as determined by MRA and CTA was separately analyzed. Vascular invasion by MRA and CTA were analyzed with kappa coefficients to determine agreement between the imaging methods. Results Seven cases of bone and 26 cases of soft tissue tumors were examined. SNR and CNR of the femoral artery were excellent for TWIST MRA (mean ± SD values of 317 ± 80 and 276 ± 76, respectively). Based on the TWIST sequence, the vessels were free of tumor in 16 cases. Vascular displacement was found in 11 cases and vascular stenosis in six cases. The MRA findings conflicted with CTA findings in only one case. The kappa value was 0.953 ( P < 0.01). In five cases, vascular malformations were found with TWIST MRA but not CTA. Conclusion TWIST MRA enables accurate delineation of anatomical structures and tumor arterial involvement, providing reliable preoperative imaging information with respect to lower extremity musculoskeletal tumors.

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Diagnosis and Treatment of a Patient with Recurrence of Multiple Soft Tissue Tumors in Left Lower Extremity after Twice Operations for 2 Years with Unclear Pathological Diagnosis and Obstructive Jaundice

Asian Case Reports in Oncology ◽

10.12677/acrpo.2014.31001 ◽

2014 ◽

Vol 03 (01) ◽

pp. 1-5

Author(s):

曦夏

Keyword(s):

Soft Tissue ◽

Obstructive Jaundice ◽

Lower Extremity ◽

Soft Tissue Tumors ◽

Pathological Diagnosis ◽

Diagnosis And Treatment ◽

Left Lower Extremity

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Undifferentiated pleomorphic sarcoma: Diagnosis of exclusion

Asian Journal of Oncology ◽

10.4103/asjo.asjo_34_17 ◽

2017 ◽

Vol 03 (02) ◽

pp. 133-135

Author(s):

Pragati S. Upasham ◽

Sharayu P. Dighavkar ◽

Prakash M. Roplekar

Keyword(s):

Soft Tissue ◽

Lower Extremity ◽

Fibrous Histiocytoma ◽

Soft Tissue Sarcomas ◽

Soft Tissue Tumors ◽

High Grade ◽

Undifferentiated Pleomorphic Sarcoma ◽

Malignant Soft Tissue Tumors ◽

Pleomorphic Sarcoma ◽

Malignant Soft Tissue

AbstractMalignant soft-tissue tumors which were designated as malignant fibrous histiocytoma are regrouped by the WHO (in 2002) under the new entity termed as “undifferentiated pleomorphic sarcoma.”1 It accounts for less than 5% of all adult soft-tissue sarcomas. Here, we report the lesion in a 70-year-old man who presented with high-grade undifferentiated pleomorphic sarcoma in the lower extremity.

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Angioleiomyoma: Clinical Presentation and Surgical Management

Foot & Ankle International ◽

10.1177/107110070102200810 ◽

2001 ◽

Vol 22 (8) ◽

pp. 670-674 ◽

Cited By ~ 8

Author(s):

Ben John Yates

Keyword(s):

Soft Tissue ◽

Lower Extremity ◽

Surgical Management ◽

Clinical Presentation ◽

Subcutaneous Tissue ◽

Soft Tissue Tumors ◽

Secondary Compression

Angioleiomyomas are relatively rare, benign, vascular soft tissue tumors with a predilection for the lower extremity. They may occur in either the cutaneous or subcutaneous tissue and are usually well encapsulated. Erosion of adjacent bone due to secondary compression phenomenon has rarely been reported in the literature. This study describes three cases.

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Localization of Gallium-67 in Peritoneal Cells by Electron Microscopic Autoradiography

Proceedings, annual meeting, Electron Microscopy Society of America ◽

10.1017/s0424820100072460 ◽

1973 ◽

Vol 31 ◽

pp. 404-405

Author(s):

D. C. Swartzendruber ◽

Norma L. Idoyaga-Vargas

Keyword(s):

Clinical Trials ◽

Soft Tissue ◽

Tumor Tissue ◽

Soft Tissue Tumors ◽

Clinical Usefulness ◽

Electron Microscopic ◽

Normal Cells ◽

Electron Microscopic Autoradiography ◽

Peritoneal Cells ◽

Gallium 67

The radionuclide gallium-67 (67Ga) localizes preferentially but not specifically in many human and experimental soft-tissue tumors. Because of this localization, 67Ga is used in clinical trials to detect humar. cancers by external scintiscanning methods. However, the fact that 67Ga does not localize specifically in tumors requires for its eventual clinical usefulness a fuller understanding of the mechanisms that control its deposition in both malignant and normal cells. We have previously reported that 67Ga localizes in lysosomal-like bodies, notably, although not exclusively, in macrophages of the spocytaneous AKR thymoma. Further studies on the uptake of 67Ga by macrophages are needed to determine whether there are factors related to malignancy that might alter the localization of 67Ga in these cells and thus provide clues to discovering the mechanism of 67Ga localization in tumor tissue.

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Benign Skin and Soft-Tissue Tumors of the Hand

Clinics in Plastic Surgery ◽

10.1016/s0094-1298(20)30610-6 ◽

1987 ◽

Vol 14 (2) ◽

pp. 403-412

Author(s):

Saleh M. Shenaq

Keyword(s):

Soft Tissue ◽

Soft Tissue Tumors ◽

Tumors Of The Hand

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Percutaneous Imaging-Guided versus Open Musculoskeletal Biopsy: Concepts and Controversies

Seminars in Musculoskeletal Radiology ◽

10.1055/s-0040-1717113 ◽

2020 ◽

Vol 24 (06) ◽

pp. 667-675

Author(s):

Violeta Vasilevska Nikodinovska ◽

Slavcho Ivanoski ◽

Milan Samardziski ◽

Vesna Janevska

Keyword(s):

Soft Tissue ◽

Complication Rate ◽

Core Needle Biopsy ◽

Multidisciplinary Team ◽

Gold Standard ◽

Needle Biopsy ◽

Soft Tissue Tumors ◽

Open Biopsy ◽

Core Needle ◽

Similar Accuracy

AbstractBone and soft tissue tumors are a largely heterogeneous group of tumors. Biopsy of musculoskeletal (MSK) tumors is sometimes a challenging procedure. Although the open biopsy is still considered the gold standard for the biopsy of MSK lesions, core needle biopsy can replace it in most cases, with similar accuracy and a low complication rate. The biopsy should be performed in a tertiary sarcoma center where the multidisciplinary team consists of at minimum a tumor surgeon, an MSK pathologist, and an MSK radiologist who can assess all steps of the procedure. Several factors can influence the success of the biopsy including the lesion characteristics, the equipment, and the method used for the procedure. This review highlights some of the important aspects regarding the biopsy of the MSK tumors, with special attention to imaging a guided core needle biopsy and highlighting some of the recent advancements and controversies in the field.

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