Synthesis of PF-1247324, a NaV1.8 Sodium Channel Modulator

Synfacts ◽  
2010 ◽  
Vol 2010 (04) ◽  
pp. 0385-0385
Keyword(s):  
Sodium Channel ◽  
Nav1.8 Sodium Channel ◽  
Channel Modulator

Optimisation of Permanganate Oxidation and Suzuki−Miyaura Coupling Steps in the Synthesis of a Nav1.8 Sodium Channel Modulator

2010 ◽  
Vol 14 (1) ◽  
pp. 263-271 ◽  
Author(s):  
M. Jonathan Fray ◽  
Adam T. Gillmore ◽  
Melanie S. Glossop ◽  
David J. McManus ◽  
Ian B. Moses ◽  
...  
Keyword(s):  
Sodium Channel ◽  
Permanganate Oxidation ◽  
Nav1.8 Sodium Channel ◽  
Channel Modulator

scholarly journals Unexpected Efficacy of a Novel Sodium Channel Modulator in Dravet Syndrome

2017 ◽  
Vol 7 (1) ◽  
Author(s):  
Lyndsey L. Anderson ◽  
Nicole A. Hawkins ◽  
Christopher H. Thompson ◽  
Jennifer A. Kearney ◽  
Alfred L. George
Keyword(s):  
Sodium Channel ◽  
Dravet Syndrome ◽  
Channel Modulator

Localization of the Nav1.8 sodium channel isoform at nodes of Ranvier in normal human radicular tooth pulp

2005 ◽  
Vol 380 (1-2) ◽  
pp. 32-36 ◽  
Author(s):  
Michael A. Henry ◽  
Howard J. Sorensen ◽  
Lonnie R. Johnson ◽  
S. Rock Levinson
Keyword(s):  
Sodium Channel ◽  
Tooth Pulp ◽  
Nodes Of Ranvier ◽  
Normal Human ◽  
Nav1.8 Sodium Channel

Molecular determinant of Nav1.8 sodium channel resistance to the venom from the scorpion Leiurus quinquestriatus hebraeus

2002 ◽  
Vol 331 (2) ◽  
pp. 79-82 ◽  
Author(s):  
Carl Y. Saab ◽  
Theodore R. Cummins ◽  
Sulayman D. Dib-Hajj ◽  
Stephen G. Waxman
Keyword(s):  
Sodium Channel ◽  
Channel Resistance ◽  
Molecular Determinant ◽  
Nav1.8 Sodium Channel

Parkinson’s disease-like forelimb akinesia induced by BmK I, a sodium channel modulator

2016 ◽  
Vol 308 ◽  
pp. 166-176 ◽  
Author(s):  
Hongyan Zhu ◽  
Ziyi Wang ◽  
Jiahui Jin ◽  
Xiao Pei ◽  
Yuxiao Zhao ◽  
...  
Keyword(s):  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Sodium Channel ◽  
Bmk I ◽  
Channel Modulator
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