ChemInform Abstract: Conformational Analysis of the Sodium Channel Modulator, Brevetoxin A, Comparison with Brevetoxin B Conformations, and a Hypothesis About the Common Pharmacophore of the “Site 5” Toxins.

ChemInform ◽  
2010 ◽  
Vol 25 (39) ◽  
pp. no-no
Author(s):  
K. S. REIN ◽  
D. G. BADEN ◽  
R. E. GAWLEY
Keyword(s):  
Conformational Analysis ◽  
Sodium Channel ◽  
Brevetoxin A ◽  
The Common ◽  
Channel Modulator

scholarly journals Unexpected Efficacy of a Novel Sodium Channel Modulator in Dravet Syndrome

2017 ◽  
Vol 7 (1) ◽  
Author(s):  
Lyndsey L. Anderson ◽  
Nicole A. Hawkins ◽  
Christopher H. Thompson ◽  
Jennifer A. Kearney ◽  
Alfred L. George
Keyword(s):  
Sodium Channel ◽  
Dravet Syndrome ◽  
Channel Modulator

Parkinson’s disease-like forelimb akinesia induced by BmK I, a sodium channel modulator

2016 ◽  
Vol 308 ◽  
pp. 166-176 ◽  
Author(s):  
Hongyan Zhu ◽  
Ziyi Wang ◽  
Jiahui Jin ◽  
Xiao Pei ◽  
Yuxiao Zhao ◽  
...  
Keyword(s):  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Sodium Channel ◽  
Bmk I ◽  
Channel Modulator

scholarly journals BDF 9148?A Sodium Channel Modulator with Positive Inotropic Action

1995 ◽  
Vol 13 (3) ◽  
pp. 260-274 ◽  
Author(s):  
Ursula Ravens ◽  
Gregory J Amos ◽  
Thomas Ehring ◽  
Gerd Heusch
Keyword(s):  
Sodium Channel ◽  
Inotropic Action ◽  
Positive Inotropic Action ◽  
Bdf 9148 ◽  
Channel Modulator

Interaction of brevetoxin A with a new receptor site on the sodium channel

Toxicon ◽  
1985 ◽  
Vol 23 (3) ◽  
pp. 497-504 ◽  
Author(s):  
William A. Catterall ◽  
Marjorie Gainer
Keyword(s):  
Sodium Channel ◽  
Receptor Site ◽  
Brevetoxin A

scholarly journals The novel sodium channel modulator GS-458967 (GS967) is an effective treatment in a mouse model of SCN8A encephalopathy

Epilepsia ◽  
2018 ◽  
Vol 59 (6) ◽  
pp. 1166-1176 ◽  
Author(s):  
Erin M. Baker ◽  
Christopher H. Thompson ◽  
Nicole A. Hawkins ◽  
Jacy L. Wagnon ◽  
Eric R. Wengert ◽  
...  
Keyword(s):  
Mouse Model ◽  
Sodium Channel ◽  
Effective Treatment ◽  
The Novel ◽  
Channel Modulator

4-Substituted carbamazepine derivatives: Conformational analysis and sodium channel-blocking properties

2018 ◽  
Vol 26 (9) ◽  
pp. 2508-2513 ◽  
Author(s):  
Yuki Kanase ◽  
Takafumi Kitada ◽  
Hidetsugu Tabata ◽  
Kosho Makino ◽  
Tetsuta Oshitari ◽  
...  
Keyword(s):  
Conformational Analysis ◽  
Sodium Channel ◽  
Channel Blocking
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