Analysis of ED-A+ fibronectin expression after heterotopic rat heart transplantation: association to cardiac allograft rejection and implications for targeted post-transplant therapy

2010 ◽  
Vol 58 (S 01) ◽  
Author(s):  
M Franz ◽  
A Berndt ◽  
K Grün ◽  
P Richter ◽  
H Kosmehl ◽  
...  
Keyword(s):  
Heart Transplantation ◽  
Allograft Rejection ◽  
Rat Heart ◽  
Cardiac Allograft ◽  
Cardiac Allograft Rejection ◽  
Post Transplant ◽  
Fibronectin Expression

scholarly journals Feasibility of Computed Tomography Perfusion for Detection of Cardiac Allograft Rejection Following Heart Transplantation

2020 ◽  
Vol 13 (5) ◽  
pp. 1286-1289
Author(s):  
Anna Oleksiak ◽  
Małgorzata Sobieszczańska-Małek ◽  
Mariusz Kruk ◽  
Tomasz Zieliński ◽  
Anna Drohomirecka ◽  
...  
Keyword(s):  
Computed Tomography ◽  
Heart Transplantation ◽  
Allograft Rejection ◽  
Cardiac Allograft ◽  
Cardiac Allograft Rejection ◽  
Computed Tomography Perfusion

Immunomodulatory effects of mesenchymal stem cells for the treatment of cardiac allograft rejection

2020 ◽  
pp. 153537022097865
Author(s):  
Zhichao Wu ◽  
Jialiang Liang ◽  
Wei Huang ◽  
Lin Jiang ◽  
Christian Paul ◽  
...  
Keyword(s):  
Stem Cells ◽  
Mesenchymal Stem Cells ◽  
Heart Transplantation ◽  
Broad Spectrum ◽  
Allograft Rejection ◽  
Cardiac Allograft ◽  
Survival Prognosis ◽  
Cardiac Allograft Rejection

Heart transplantation continues to be the gold standard clinical intervention to treat patients with end-stage heart failure. However, there are major complications associated with this surgical procedure that reduce the survival prognosis of heart transplant patients, including allograft rejection, malignancies, infections, and other complications that arise from the use of broad-spectrum immunosuppression drugs. Recent studies have demonstrated the use of mesenchymal stem cells (MSCs) against allotransplantation rejection in both in vitro and in vivo settings due to their immunomodulatory properties. Therefore, utilization of MSCs provides new and exciting strategies to improve heart transplantation and potentially reduce the use of broad-spectrum immunosuppression drugs while alleviating allograft rejection. In this review, we will discuss the current research on the mechanisms of cardiac allograft rejection, the physiological and immunological characteristics of MSCs, the effects of MSCs on the immune system, and immunomodulation of heart transplantation by MSCs.

Natural Course of Moderate Cardiac Allograft Rejection (International Society for Heart Transplantation Grade 2) Early and Late After Transplantation

Circulation ◽  
1996 ◽  
Vol 94 (6) ◽  
pp. 1334-1338 ◽  
Author(s):  
Hans P. Brunner-La Rocca ◽  
Gabor Su¨tsch ◽  
Jakob Schneider ◽  
Ferenc Follath ◽  
Wolfgang Kiowski
Keyword(s):  
Heart Transplantation ◽  
International Society ◽  
Allograft Rejection ◽  
Cardiac Allograft ◽  
Natural Course ◽  
Cardiac Allograft Rejection
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