Prevalence of thyroid dysfunction and age dependency of TSH in a population-based study: Results from the Heinz Nixdorf Recall Study (HNR)

2013 ◽  
Vol 121 (03) ◽  
Author(s):  
P Muchalla ◽  
S Schramm ◽  
H Lahner ◽  
U Roggenbuck ◽  
S Moebus ◽  
...  
Author(s):  
Juan Fraile ◽  
Rodrigo Pardo ◽  
Ernesto Panadero

Resumen:El Proceso de Bolonia concibe la evaluación como parte del proceso de enseñanza-aprendizaje, denominándose ‘evaluación formativa’, pudiendo ser la autoevaluación una parte esencial del mismo. Esta se entiende como dos acciones: metodología de enseñanza-aprendizaje; o autocalificación, evaluándose cuantitativamente con repercusión en la nota final. Se analizaron 1.761 guías docentes de las asignaturas de 40 universidades españolas que imparten presencialmente el Grado en Ciencias de la Actividad Física y del Deporte, siendo un estudio con el 100 % de la población. Los resultados mostraron que el 7,55 % de las asignaturas emplea la autoevaluación como metodología de enseñanza-aprendizaje; el 9,43 % como autocalificación y el 1,65 % emplea ambas; encontrando diferencias significativas en función de la titularidad, la universidad, la comunidad autónoma y el número de créditos. Estos resultados son muy inferiores comparados con un estudio con datos autorreportados por docentes (Panadero, Brown, y Courtney, 2014), declarando el 89,7 % emplear la autoevaluación y el 66,2 % la autocalificación. Esta investigación constituye su relevancia al aportar una completa visión sobre la implementación de la autoevaluación y la autocalificación en el grado de Ciencias de la Actividad Física y del Deporte en España. Abstract:The Bologna Process understands assessment as a part of the teaching and learning process. It is so-called formative assessment, being self-assessment an essential part of it. Self-assessment can be conceived having two potential actions. First, as a teaching and learning method, being its purpose to teach students how to assess their own work. Second, as self-grading, in order to grade their own achievement with direct impact in their final mark of the course. This study aims to explore the use of self-assessment and self-grading processes in the Degree in Sport Science. 1,761 teaching guides from the syllabus of the 40 Spanish university faculties with attendance studies were analyzed. Thus, this is a population-based study. Results showed that self-assessment is presumably used in 14.99% of subjects: 7.55% with formative purposes, 9.43% as self-grading and 1.65% employ both. Significant differences were found for ownership, university, region and number of credits. Increased use in some regions and universities shows the territorial influence and the existence of teachers´ communities of practice. These results are far lower compared both to another similar research based on self-reported data collected by surveys (Panadero, Brown, & Courtney, 2014), in which 89.7% of teachers reported they use self-assessment and 66.2% self-grading. Therefore, this research is relevant to provide a suitable overview of the implementation of self-assessment and self-grading in the Degree in Sports Science.


2005 ◽  
pp. 108-113
Author(s):  
O. V. Mishchenko ◽  
V. V. Pavlov ◽  
V. I. Kupaev

The aim of the study was to analyze granted drug provision for asthma (BA) patients at Samara region to spend healthcare resources more rationally and to improve asthma patients' quality of life. This population-based study of drug therapy involved 19,697 BA patients surveyed at Samara region in 2003–2004. The analysis was performed using a personified database of the granted drug provision and integral parameters of health. We used multi-factorial statistical analysis with mathematical modelling. The results demonstrated that the healthcare quality for BA patients depends on a structure of the drug therapy. A model of basic anti-asthmatic therapy for Samara region was created using the study results.


Author(s):  
Beate Koch ◽  
Thomas Penzel ◽  
Ingo Fietze ◽  
Carmen Garcia ◽  
Sandra Zimmermann ◽  
...  

Menopause ◽  
2021 ◽  
Vol Publish Ahead of Print ◽  
Author(s):  
Susanna M. Savukoski ◽  
Maarit J. Niinimäki ◽  
Paula R.O. Pesonen ◽  
Juha P. Auvinen ◽  
Tuija Männistö ◽  
...  

2021 ◽  
Vol 13 (1) ◽  
Author(s):  
Sara Schramm ◽  
Martha Jokisch ◽  
Karl-Heinz Jöckel ◽  
Arne Herring ◽  
Kathy Keyvani

Abstract Background Kallikrein-8 (KLK8) might be an early blood-biomarker of Alzheimer’s disease (AD). We examined whether blood KLK8 is elevated in persons with amnestic mild cognitive impairment (aMCI) which is a precursor of AD, compared to cognitively unimpaired (CU) controls. Methods Forty cases and 80 controls, matched by sex and age (± 3years), were participants of the longitudinal population-based Heinz Nixdorf Recall study (baseline: 2000–2003). Standardized cognitive performance was assessed 5 (T1) and 10 years after baseline (T2). Cases were CU at T1 and had incidental aMCI at T2. Controls were CU at T1 and T2. Blood KLK8 was measured at T2. Using multiple logistic regression the association between KLK8 in cases vs. controls was investigated by estimating odds ratios (OR) and 95% confidence intervals (95%CI), adjusted for inter-assay variability and freezing duration. Using receiver operating characteristic (ROC) analysis, the diagnostic accuracy of KLK8 was determined by estimating the area under the curve (AUC) and 95%CI (adjusted for inter-assay variability, freezing duration, age, sex). Results Thirty-seven participants with aMCI vs. 72 CU (36.7%women, 71.0±8.0 (mean±SD) years) had valid KLK8 measurements. Mean KLK8 was higher in cases than in controls (911.6±619.8 pg/ml vs.783.1±633.0 pg/ml). Fully adjusted, a KLK8 increase of 500pg/ml was associated with a 2.68 (1.05–6.84) higher chance of having aMCI compared to being CU. With an AUC of 0.92 (0.86–0.97), blood KLK8 was a strong discriminator for aMCI and CU. Conclusion This is the first population-based study to demonstrate the potential clinical utility of blood KLK8 as a biomarker for incipient AD.


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