Double-wire versus Single-wire Sternal Closure in Obese Patients - A Randomized Prospective Study to Avoid Sternal Instability by Use of Double Wires in CABG Patients

2015 ◽  
Vol 63 (S 01) ◽  
Author(s):  
G. Loladze ◽  
R.U. Kühnel ◽  
T. Claus ◽  
J.M. Albes
2016 ◽  
Vol 65 (04) ◽  
pp. 332-337 ◽  
Author(s):  
Ralf Kuehnel ◽  
Thomas Claus ◽  
Martin Hartrumpf ◽  
Frank Kuepper ◽  
Manfred Pohl ◽  
...  

Background Sternal instability after coronary artery bypass grafting (CABG) is a serious complication. Obese patients are at high risk for sternal instability after CABG. This study was conducted to assess the positive impact of double-wire sternal closure on sternal instability. Methods A total of 200 obese patients with a body mass index ≥ 30 kg/m2 undergoing isolated CABG with left internal mammary artery (LIMA) graft were randomly assigned to sternal closure either by eight single wires (n = 100) or by a combination of four double wires and four single wires. Results There was a total of 21 cases with sternal instability: 5 cases (i.e., 5%) in the double-wire group versus 16 cases (16%) in the single-wire group (p = 0.019). Logistic regression analysis showed sternal closure via double wires as an independent protection factor (odds ratio [OR]: 0.276; p = 0.029). Smoking (OR: 5.5; p = 0.006) and postoperative delirium (OR: 3.5; p = 0.033) turned out to be independent risk factors for the development of sternal instability. Conclusion Double-wire sternal closure significantly reduces postoperative sternal instability in obese patients undergoing isolated CABG with LIMA graft.


2021 ◽  
Vol 108 (Supplement_6) ◽  
Author(s):  
Ahmed Mohamed Abdel Shafi ◽  
Eyad Abuelgasim ◽  
Biyaser Abuelgasim ◽  
Sashini Iddawela ◽  
Amer Harky

Abstract Aim Sternal instability and wound infections are a major cause of morbidity following cardiac surgery, which is further amplified in high-risk patients that include diabetics and patients with high BMI. We compare the different outcomes of different sternal wire closure techniques following median sternotomy for cardiac surgery in obese patients Method A comprehensive electronic literature search was undertaken according to PRISMA guidelines from inception to July 2020 to identify all published data comparing single wire sternal closure to either double wire or figure-of-8 techniques following median sternotomy for cardiac surgery in obese patients, defined as a BMI ≥ 30. Results Eight studies met the final inclusion criteria; single wire versus double wire sternal closure (n = 2) and single wire versus figure-of-8 wire closure (n = 6). Higher rate of sternal instability was noted in single wire vs double wire closure (22/150 (14.7%) patients vs 6/150 (4%) patients, p = 0.003, OR 0.25 [95% CI 0.10-0.63]). Similarly, sternal instability was higher in single wire vs figure-of-8 wire closure technique (33/2422 (1.3%) vs 11/8035 (0.1%), p = 0.04 OR 0.30 [95% CI, 0.09-0.96]) respectively. Conclusions There is benefit in the use of either double or figure-of-8 sternal wire closure techniques over single wire closure in terms of sternal instability. However, as the studies were limited, larger scale comparative studies are required to provide a solid evidence base for choosing the optimal sternal closure technique in this high-risk group of patients.


2014 ◽  
Vol 24 (6) ◽  
pp. 903-908 ◽  
Author(s):  
Verónica Gumbau ◽  
Marcos Bruna ◽  
Enrique Canelles ◽  
Marcos Guaita ◽  
Claudia Mulas ◽  
...  

2020 ◽  
Vol 3 (1) ◽  
pp. 142-148
Author(s):  
Venkat Vaijnath Cholleti ◽  
Mohd. Ilyas

Background: There is a dynamic and reciprocal interaction among ECM and involving cells, cytokines, growth factors and proteases (MMP/TIMP). The controlled degradation of ECM by extracellular proteases particularly MMP/TIMP and serene proteases forms the basis of wound healing. To study clinical factors (BMI, DM) influencing healing of acute abdominal surgical wounds as graded by tissue expression of MMP 2, MMP 9 and TIMP. Subjects and Methods: The present study was conducted in 46 patients in the Department of General Surgery, Kamineni Hospitals, L.B. Nagar, Hyderabad. Results: Type II DM was found in 63 % of patients and found to be having significantly affecting wound healing (p = 0.0017). Wound healing was delayed in uncontrolled DM. Diabetics with healed wound had increased expression of MMP-2 and decreased expression of MMP-9 while Diabetics with non-healed had strong expression of MMP-9 and TIMP as compared to MMP-2. Obesity was seen in 47.82 % of patients and significantly affected wound healing (p = 0.0022). Obese patients with healed wounds had increased expression of MMP-2 and MMP – 9 with decreased TIMP levels. Conclusion: The present study strongly supported tissue expression of MMP-2, MMP-9 and TIMP 2 balance between 7-14 days as a good predictor of wound healing in abdominal laprotomy wounds.


2005 ◽  
Vol 80 (4) ◽  
pp. 1537-1539 ◽  
Author(s):  
Arndt-H. Kiessling ◽  
Frank Isgro ◽  
Udo Weisse ◽  
Andreas Möltner ◽  
Werner Saggau ◽  
...  

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