Severe Hemolysis after Paravalvular Leak Closure of a Mitral Prosthesis with an Amplatzer Device

2015 ◽  
Vol 63 (S 01) ◽  
Author(s):  
S. Schneider ◽  
A. Dell'Aquila ◽  
H. Deschka ◽  
S. Martens ◽  
A. Rukosujew
Author(s):  
Fabiola Sozzi ◽  
Franck Levy ◽  
Francois Bourlon ◽  
Nicolas Hugues ◽  
Laura Iacuzio ◽  
...  

A case of a severe paravalvular mechanical mitral prosthesis leak in a high-risk patient that underwent previously 4 mitral valve surgeries is described. An Amulet-Amplatzer device was correctly implanted on the left atrial appendage, with the temptative to close also the contiguous severe leak. A residual moderate paravalvular leak caused acute hemolysis with severe renal failure requiring hemodialysis. The transesophageal echocardiogram is crucial in localizing and defining the extent of the paravalvular leak. It is not clear if the hemolysis was precipitated by the evolution of the disease or by the residual regurgitation after Amulet device deployment. Certainly, given the intricacy of the procedure the results might be limited also for highly expert operators. To our knowledge, this is the first case reporting the use of the Amulet-Amplatzer device for paravalvular leak closure.


2018 ◽  
Vol 6 (1) ◽  
pp. 25-27
Author(s):  
Alexandra Pavel

Background: Paraprosthetic leak is a complication of mitral and aortic valve implantation interventions, that can be treated either through a surgical procedure (repair or replacement of the prosthesis) or by means of a less-invasive percutaneous transcatheter approach. Nevertheless, this percutaneous intervention carries complications on its own, one of them being displacement of the occluder device. Results: This is the case of a 66-year-old patient, with a clinical history of two mitral valve replacement procedures, who presented with dyspnea, fatigue, and peripheral edema. Echocardiographic findings described severe mitral regurgitation due to the presence of a paravalvular leak. Considering the high perioperative mortality, renal and respiratory impairment, and the fact that this reoperation would have been the third cardiac surgery for the patient, percutaneous transcatheter closure of the leak was recommended. Four days after the successful procedure, a checkup echocardiogram revealed the migration of the occluder device to the left atrial cavity. Even though the operative risk was high and the prognosis poor, the only available treatment option was the surgical management that achieved the removal of the device and replacement of the diseased prosthesis. Conclusion: Albeit less invasive, lower risks, and better outcomes, the percutaneous intervention for leak closure has some clinically relevant complications that must be addressed promptly. One of these complications – detachment of the occluder device – even if quite rare, is a significant event that requires immediate surgical or interventional approach. A careful postoperative checkup is therefore essential to detect any complication and to address it directly.


2012 ◽  
Vol 65 (3) ◽  
pp. 287
Author(s):  
Manuel Carnero Alcázar ◽  
Luis Carlos Maroto Castellanos ◽  
José Enrique Rodríguez Hernández

2012 ◽  
Vol 8 (5) ◽  
pp. 638-639
Author(s):  
Nawwar Al-Attar ◽  
Ghada Al-Salih ◽  
Soleiman Alkhoder ◽  
Costin Radu ◽  
Richard Raffoul ◽  
...  

2013 ◽  
Vol 16 (1) ◽  
pp. 21 ◽  
Author(s):  
Salah Eldien Altarabsheh ◽  
Salil V. Deo ◽  
Charanjit S. Rihal ◽  
Soon J. Park

<p>A frail 70-year-old woman presented with symptomatic mitral paravalvular leak 2 months after undergoing a double valve replacement for mixed mitral and aortic valve disease. There was no evidence of prosthetic valve endocarditis. Percutaneous closure of the paravalvular leak was attempted as an alternative to a high-risk surgical procedure. This therapy was successful in reducing the regurgitation but resulted in severe intravascular hemolysis and acute renal failure requiring hemodialysis.</p><p>The development of new hemolysis and acute renal failure directed our attention to the Amplatzer device as a possible etiology for these complications. The assumption that her kidney injury was recent and likely reversible compelled us to think of the surgical method as a definitive option. A re-operative surgery was performed, which included retrieval of the occluder devices, pericardial patch repair, and re-replacement using a new biological prosthesis. The patient's urine output gradually improved, and the patient was dismissed with normal renal function.</p><p>We present this case as an unusual complication of percutaneous device closure. It also highlights the reversible nature of acute renal failure due to intravascular hemolysis and demonstrates the importance of early surgical intervention for this condition.</p>


2014 ◽  
Vol 148 (5) ◽  
pp. 1965-1969 ◽  
Author(s):  
Giedrius Davidavicius ◽  
Kestutis Rucinskas ◽  
Agne Drasutiene ◽  
Robertas Samalavicius ◽  
Valdas Bilkis ◽  
...  

Sign in / Sign up

Export Citation Format

Share Document