Preoperative plasma fibrinogen levels predict mortality after coronary artery bypass grafting

2003 ◽  
Vol 89 (05) ◽  
pp. 885-891 ◽  
Author(s):  
Daniel Robinson ◽  
Volker Kleine ◽  
Sabine Hertwig ◽  
Christian Schwahn ◽  
Rita Grimm ◽  
...  
Keyword(s):  
Coronary Artery ◽  
Coronary Artery Bypass ◽  
Artery Bypass ◽  
Bypass Graft ◽  
Multivariable Analysis ◽  
Myocardial Revascularization ◽  
Total Mortality ◽  
Plasma Fibrinogen ◽  
Entire Cohort ◽  
End Point

SummaryThis study was designed to investigate whether plasma fibrinogen levels as well as the β-fibrinogen –455 G/A genotype are associated with outcome after coronary artery bypass graft (CABG) operation.We enrolled 249 consecutive CAD patients one day before they underwent a CABG operation. Data from 220 patients with available plasma fibrinogen levels were analyzed. The primary end-point was total mortality, the secondary end-point mortality from cardiac causes or the need for myocardial revascularization. The 2-year total mortality was 9.1% in the entire cohort. Multivariable analysis revealed an independent relationship between the primary end-point and preoperative plasma fibrinogen levels but not the β-fibrinogen –455 G/A geno-type. Neither preoperative plasma fibrinogen levels nor the β-fibrinogen –455 G/A genotype could predict the secondary end-point.We conclude, that elevated preoperative plasma fibrinogen levels, but not the β-fibrinogen -455 G/A genotype predict the total mortality after CABG operation.

SYNTAX score and coronary artery bypass graft surgery in Bangladesh

2019 ◽  
Vol 27 (7) ◽  
pp. 542-547
Author(s):  
Redoy Ranjan ◽  
Asit Baran Adhikary
Keyword(s):  
Coronary Artery Disease ◽  
Coronary Artery ◽  
Coronary Artery Bypass Graft ◽  
Coronary Artery Bypass ◽  
Artery Bypass ◽  
Bypass Graft ◽  
Myocardial Revascularization ◽  
Syntax Score ◽  
Artery Bypass Graft ◽  
Artery Disease

Background The SYNTAX score is a helpful tool for determining the optimal myocardial revascularization strategy in complex coronary artery disease. The aim of this study was to assess whether the SYNTAX score predicts postoperative mortality in patients undergoing coronary artery bypass grafting. Methods The study included 1100 consecutive patients referred for coronary artery bypass graft surgery over a 4-year period. Angiographic data were interpreted by both experienced intervention cardiologists and cardiac surgeons. The patients were divided into three groups based on SYNTAX score tertiles: low ≤22 ( n =  560), intermediate 23–32 ( n =  360), and high ≥33 ( n =  180). Results Compared to patients with a low SYNTAX score, those with intermediate and high scores were significantly older ( p <  0.001), had a lower left ventricular ejection fraction ( p <  0.001), higher pulmonary artery pressure ( p <  0.001), and higher incidences of acute coronary syndrome and left main coronary artery disease. A significantly higher EuroSCORE ( p =  0.003) was also observed in patients with a higher SYNTAX score. Patients with intermediate and high SYNTAX scores had higher 5-year mortality rates (18.6% and 19.5%, respectively) than patients with low SYNTAX scores (9.5%, p <  0.05). In multivariate analysis, SYNTAX score was not an independent predictor of late mortality. Conclusion Although SYNTAX score is not independently predictive of late mortality in patients with complex coronary artery disease undergoing myocardial revascularization surgery, patients with lower SYNTAX scores had a lower mortality rate after coronary artery bypass graft surgery.

scholarly journals Outcome of Coronary Artery Bypass Graft Surgery with Coronary Endarterectomy

2019 ◽  
Vol 44 (3) ◽  
pp. 124-131
Author(s):  
R Ranjan ◽  
AB Adhikary
Keyword(s):  
Coronary Artery Disease ◽  
Coronary Artery ◽  
Coronary Artery Bypass ◽  
Artery Bypass ◽  
Bypass Graft ◽  
Myocardial Revascularization ◽  
Atheromatous Plaque ◽  
Coronary Endarterectomy ◽  
Diffuse Coronary Artery Disease ◽  
Artery Disease

Background: Coronary Endarterectomy (CE) is the expulsion of the atheromatous plaque, and isolating the outer media and adventitia layers of arterial wall. Objective of this study was to review the consequences of coronary endarterectomy (CE) with coronary artery bypass grafting (CABG), and demonstrate the outcomes of this surgical technique for patients with diffuse coronary artery disease in a single surgeon’s practice. Methods: Retrospectively outcome of 1473 endarterectomised coronary artery in 1189 patients with diffuse coronary artery disease (CAD) was reviewed, who have had experienced CE with OPCABG in the year of 2007 to 2016. CE was performed in multi-segmental diffuse CAD, or when a calcified or extremely thick plaque making anastomosis troublesome. Results: Approximately 75.0% coronary endarterectomy were performed in the left coronary territory and most commonly left anterior descending artery was endarterectomized (42.83%). An average of 1.2 coronary endarterectomies performed per patient. Post-operative ICU and 30-days mortality rate was 2.2%, and 0.6% respectively in CE group. Post-operative atrial fibrillation, acute MI, neurological complication, and blood transfusion were significantly higher in CE group. Following CE, Kaplan–Meier cumulative survival rate was 89.5%, and about 85% patients were free from angina at follow-up of 5 years. Conclusion: Coronary endarterectomy with OPCABG is attainable, and accomplishes surgical revascularization in patients; when there is no other alternative for total myocardial revascularization. Bangladesh Med Res Counc Bull 2018; 44: 124-131

scholarly journals Clinical Outcomes for Radial Artery Versus Saphenous Vein in Coronary Artery Bypass Graft Surgery

2018 ◽  
Vol 13 (1) ◽  
pp. 21-25
Author(s):  
AKM Manzurul Alam ◽  
Istiaq Ahmed ◽  
Manzil Ahmad ◽  
Md Mohashinreza ◽  
Mamun Hossain ◽  
...  
Keyword(s):  
Coronary Artery ◽  
Clinical Outcome ◽  
Clinical Outcomes ◽  
Coronary Artery Bypass ◽  
Radial Artery ◽  
Saphenous Vein ◽  
Artery Bypass ◽  
Bypass Graft ◽  
Myocardial Revascularization ◽  
Young Patients

Aims: The aim this study was to see the clinical outcome of coronary artery bypass grafting (CABG) in patients of coronary artery disease and to compare the patients revascularisedwith left internal mammary artery (LIMA) and radial artery (RA) group with LIMA and reverse saphenous venous group(RSVG) group.Methods:Between March 2011 and November 2015, 200 patients underwent isolated CABG and were randomized in 1:1 fashion to receive either LIMA and RA grafts or LIMA and SVGs.All patients were operated in department of cardiac surgery, National Institute of Cardiovascular Disease (NICVD) and Hospital, Dhaka, Bangladesh and Al Helal Specialized Hospital, Mirpur- 10, Dhaka.Written consent was obtained from all patients prior to the procedure. Patients were followed for 4 years since index surgery for the composite of cardiovascular mortality, non-fatal myocardial infarction and need for repeat myocardial revascularization (either surgical or percutaneous). Data were collected either by phone or during visits. The data were entered into an electronic database (Access, Microsoft) and analyzed using the SPSS 16.0 software (SPSS Inc.).Results: This study reports on our series of 200 patients undergoing isolated, primary CABG using LIMA grafting and the SVG in one group, and RA grafting as the second conduit in the second group. Our data indicate that there is no difference in the long-term clinical outcome between the patients in whom RA or SVG is used as a second conduit, beside LIMA.Conclusion: In this small randomized study our data indicate that there is no difference in the 4 year clinical outcomes in relatively young patients between those having a RA or a saphenous vein graft used as a second conduit, beside LIMA, for surgical myocardial revascularization.University Heart Journal Vol. 13, No. 1, January 2017; 21-25

scholarly journals Coronary Artery Bypass Graft Surgery: The Past, Present, and Future of Myocardial Revascularisation

2014 ◽  
Vol 2014 ◽  
pp. 1-6 ◽  
Author(s):  
Michael Diodato ◽  
Edgar G. Chedrawy
Keyword(s):  
Coronary Artery ◽  
Coronary Artery Bypass Graft ◽  
Coronary Artery Bypass ◽  
Artery Bypass ◽  
Bypass Graft ◽  
Myocardial Revascularization ◽  
Artery Bypass Graft ◽  
Patient Profile ◽  
The Rich ◽  
Cardiac Surgeons

The development of the heart-lung machine ushered in the era of modern cardiac surgery. Coronary artery bypass graft surgery (CABG) remains the most common operation performed by cardiac surgeons today. From its infancy in the 1950s till today, CABG has undergone many developments both technically and clinically. Improvements in intraoperative technique and perioperative care have led to CABG being offered to a more broad patient profile with less complications and adverse events. Our review outlines the rich history and promising future of myocardial revascularization.

scholarly journals EEffect of Great Saphenous Vein Harvesting in Lower Limb Following Coronary Artery Bypass Grafting in Diabetic Patients

KYAMC Journal ◽  
2020 ◽  
Vol 11 (2) ◽  
pp. 59-61
Author(s):  
Mahbub Ahsan ◽  
Md Abul Kashem ◽  
Md Golam Kibria
Keyword(s):  
Coronary Artery ◽  
Coronary Artery Bypass ◽  
Saphenous Vein ◽  
Lower Limb ◽  
Great Saphenous Vein ◽  
Artery Bypass ◽  
Bypass Graft ◽  
Myocardial Revascularization ◽  
Diabetic Patients ◽  
Vein Harvesting

Background: Coronary artery bypass graft Surgery is an established method of myocardial revascularization. Great saphenous vein is the conduit of choice for all cardiac surgeons. Objective: To compare the effect of great saphenous vein harvesting on lower limb such as swelling, pain, discharge with diabetic and non diabetic CABG patients in whom great saphenous vein was used as a conduit. Materials and Methods: It was a cross sectional study on 60 patients who underwent CABG during July 2003 to June 2005 in department of cardiovascular surgery, National Institute of Cardiovascular Diseases (NICVD). Results: The age in group A (Diabetic) ranged from 40-72 years in group B (Non Diabetic) the age range was 40-65 years. Myocardial infarction and Congestive cardiac failure were the predominant risk factors in both age groups. There was no motor or sensory disturbances post operatively. Some patients developed swelling, tenderness, paresthesia in both group but it was not statistically significant. Conclusion: Morbidity occurs in both diabetic and non diabetic patients with certain complications like numbness, paresthesia, swelling etc. at the harvesting site. KYAMC Journal Vol. 11, No.-2, July 2020, Page 59-61

Noninvasive Follow-Up of Coronary Artery Bypass Graft Patency Using Multi-Slice Computed Tomography

2006 ◽  
Vol 55 (5) ◽  
pp. 451
Author(s):  
Seung Ho Joo ◽  
Byoung Wook Choi ◽  
Jae Seung Seo ◽  
Young Jin Kim ◽  
Tae Hoon Kim ◽  
...  
Keyword(s):  
Computed Tomography ◽  
Coronary Artery ◽  
Coronary Artery Bypass Graft ◽  
Coronary Artery Bypass ◽  
Artery Bypass ◽  
Bypass Graft ◽  
Graft Patency ◽  
Artery Bypass Graft
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