Early Epilepsy Surgery in a Patient with Infantile Spasms and Focal Seizures, Due to Focal Cortical Dysplasia, and TSC2 Gene Mutation: Considerations about the Impact of Gene Mutation on the Correct Surgical Timing in the Presurgical Evaluation

2018 ◽  
Vol 49 (S 01) ◽  
pp. S1-S12
Author(s):  
Angelo Russo ◽  
Laura Tassi ◽  
Tullio Messana ◽  
Antonella Boni ◽  
Margherita Santucci ◽  
...  
Keyword(s):  
Gene Mutation ◽  
Epilepsy Surgery ◽  
Focal Cortical Dysplasia ◽  
Cortical Dysplasia ◽  
Infantile Spasms ◽  
Tsc2 Gene ◽  
Presurgical Evaluation ◽  
Surgical Timing ◽  
Focal Seizures ◽  
The Impact

scholarly journals Applications of Intraoperative Ultrasound in Epilepsy Surgery for Focal Cortical Dysplasia

2014 ◽  
Vol 22 (1) ◽  
pp. 43-46 ◽  
Author(s):  
Cheng-Chia Lee ◽  
Chun-Fu Lin ◽  
Hsiang-Yu Yu ◽  
Sheng-Che Hung ◽  
Yang-Hsin Shih ◽  
...  
Keyword(s):  
Epilepsy Surgery ◽  
Focal Cortical Dysplasia ◽  
Intraoperative Ultrasound ◽  
Cortical Dysplasia

scholarly journals Coregistrating magnetic source and magnetic resonance imaging for epilepsy surgery in focal cortical dysplasia

2018 ◽  
Vol 19 ◽  
pp. 487-496 ◽  
Author(s):  
Burkhard S. Kasper ◽  
Karl Rössler ◽  
Hajo M. Hamer ◽  
Arnd Dörfler ◽  
Ingmar Blümcke ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Magnetic Resonance ◽  
Epilepsy Surgery ◽  
Focal Cortical Dysplasia ◽  
Cortical Dysplasia ◽  
Resonance Imaging ◽  
Magnetic Source

Sleep related epilepsy in focal cortical dysplasia type 2: Insights from sleep recordings in presurgical evaluation

2020 ◽  
Vol 131 (3) ◽  
pp. 609-615
Author(s):  
Christin M. Eltze ◽  
Elisabeth Landre ◽  
Christine Soufflet ◽  
Francine Chassoux
Keyword(s):  
Focal Cortical Dysplasia ◽  
Cortical Dysplasia ◽  
Presurgical Evaluation

scholarly journals Outcome of epilepsy surgery in focal cortical dysplasia

2003 ◽  
Vol 74 (2) ◽  
pp. 183-188 ◽  
Author(s):  
T Kral ◽  
H Clusmann ◽  
I Blumcke ◽  
R Fimmers ◽  
B Ostertun ◽  
...  
Keyword(s):  
Epilepsy Surgery ◽  
Focal Cortical Dysplasia ◽  
Cortical Dysplasia

Epilepsy surgery in the setting of periventricular leukomalacia and focal cortical dysplasia

Neurology ◽  
1996 ◽  
Vol 46 (3) ◽  
pp. 839-841 ◽  
Author(s):  
E. Wyllie ◽  
Y. Comair ◽  
P. Ruggieri ◽  
S. Raja ◽  
R. Prayson
Keyword(s):  
Epilepsy Surgery ◽  
Focal Cortical Dysplasia ◽  
Periventricular Leukomalacia ◽  
Cortical Dysplasia

scholarly journals Cognitive functioning after epilepsy surgery in children with mild malformation of cortical development and focal cortical dysplasia

2019 ◽  
Vol 94 ◽  
pp. 209-215 ◽  
Author(s):  
Tim J. Veersema ◽  
Monique M.J. van Schooneveld ◽  
Cyrille H. Ferrier ◽  
Pieter van Eijsden ◽  
Peter H. Gosselaar ◽  
...  
Keyword(s):  
Cognitive Functioning ◽  
Epilepsy Surgery ◽  
Focal Cortical Dysplasia ◽  
Cortical Development ◽  
Cortical Dysplasia ◽  
Malformation Of Cortical Development

Ultrasound assisted awake epilepsy surgery for type IIB focal cortical dysplasia in eloquent areas

2021 ◽  
Vol 65 (1) ◽  
Author(s):  
Matteo MARTINONI ◽  
Gianluca MARUCCI ◽  
Stefano MELETTI ◽  
Lilia VOLPI ◽  
Roberto MICHELUCCI ◽  
...  
Keyword(s):  
Epilepsy Surgery ◽  
Focal Cortical Dysplasia ◽  
Cortical Dysplasia ◽  
Eloquent Areas ◽  
Ultrasound Assisted

Principles of Invasive EEG

2018 ◽  
pp. 19-25
Author(s):  
Samden D. Lhatoo ◽  
Nuria Lacuey ◽  
Philippe Ryvlin
Keyword(s):  
Temporal Lobe ◽  
Epilepsy Surgery ◽  
Focal Epilepsy ◽  
Focal Cortical Dysplasia ◽  
Cortical Dysplasia ◽  
Palliative Surgery ◽  
Mesial Temporal Sclerosis ◽  
Choice Of Technique ◽  
Inappropriate Choice

The growing requirement for invasive EEG in presurgical evaluation of intractable focal epilepsy has been driven largely by the increasing complexity of epilepsy surgery cases. Extratemporal surgeries now exceed anterior temporal lobe resections for mesial temporal sclerosis, and the proportion of patients undergoing invasive EEGs has significantly increased. Half of all patients undergoing stereotactic EEG (SEEG) evaluations are MRI-negative (usually with focal cortical dysplasia type 1 or 2) and a third are reoperations for failed resective or palliative surgery. Certain principles guide the decision to use invasive EEG and the choice of invasive EEG technique. SEEG has distinct advantages, as do subdural grid evaluations and intraoperative corticography. The consequences of loose hypotheses in the decision to invasively evaluate a patient, and of inappropriate choice of technique, include poor seizure outcomes after surgery, morbidity, and mortality. This chapter discusses the guiding principles for invasive studies of the human epileptic brain.

A meta-analysis of predictors of seizure freedom in the surgical management of focal cortical dysplasia

2012 ◽  
Vol 116 (5) ◽  
pp. 1035-1041 ◽  
Author(s):  
Nathan C. Rowland ◽  
Dario J. Englot ◽  
Tene A. Cage ◽  
Michael E. Sughrue ◽  
Nicholas M. Barbaro ◽  
...  
Keyword(s):  
Seizure Control ◽  
Focal Cortical Dysplasia ◽  
Meta Analysis ◽  
Large Population ◽  
Cortical Dysplasia ◽  
Seizure Freedom ◽  
Related Factor ◽  
Medline Search ◽  
Postoperative Seizure ◽  
The Impact

Object Focal cortical dysplasia (FCD) is one of the most common causes of medically refractory epilepsy leading to surgery. However, seizure control outcomes reported in isolated surgical series are highly variable. As a result, it is not clear which variables are most crucial in predicting seizure freedom following surgery for FCD. The authors' aim was to determine the prognostic factors for seizure control in FCD by performing a meta-analysis of the published literature. Methods A MEDLINE search of the published literature yielded 37 studies that met inclusion and exclusion criteria. Seven potential prognostic variables were determined from these studies and were dichotomized for analysis. For each variable, individual studies were weighted by inverse variance and combined to generate an odds ratio favoring seizure freedom. The methods complied with a standardized meta-analysis reporting protocol. Results Two thousand fourteen patients were included in the analysis. The overall rate of seizure freedom (Engel Class I) among patients undergoing surgery for FCD in the cohort of studies was 55.8% ± 16.2%. Partial seizures, a temporal location, detection with MRI, and a Type II Palmini histological classification were associated with higher rates of postoperative seizure control. As a treatment-related factor, complete resection of the anatomical or electrographic abnormality was the most important predictor overall of seizure freedom. Neither age nor electroencephalographic localization of the ictal onset significantly affected seizure freedom after surgery. Conclusions Using a large population cohort pooled from the published literature, an analysis identified important factors that are prognostic in patients with epilepsy due to FCD. The most important of these factors—diagnostic imaging and resection—provide modalities through which improvements in the impact of FCD can be effected.

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