scholarly journals Cognitive functioning after epilepsy surgery in children with mild malformation of cortical development and focal cortical dysplasia

2019 ◽  
Vol 94 ◽  
pp. 209-215 ◽  
Author(s):  
Tim J. Veersema ◽  
Monique M.J. van Schooneveld ◽  
Cyrille H. Ferrier ◽  
Pieter van Eijsden ◽  
Peter H. Gosselaar ◽  
...  
Keyword(s):  
Cognitive Functioning ◽  
Epilepsy Surgery ◽  
Focal Cortical Dysplasia ◽  
Cortical Development ◽  
Cortical Dysplasia ◽  
Malformation Of Cortical Development

scholarly journals Long‐term seizure outcome after epilepsy surgery in patients with mild malformation of cortical development and focal cortical dysplasia

2018 ◽  
Vol 4 (1) ◽  
pp. 170-175 ◽  
Author(s):  
Tim J. Veersema ◽  
Banu Swampillai ◽  
Cyrille H. Ferrier ◽  
Pieter Eijsden ◽  
Peter H. Gosselaar ◽  
...  
Keyword(s):  
Epilepsy Surgery ◽  
Focal Cortical Dysplasia ◽  
Cortical Development ◽  
Cortical Dysplasia ◽  
Seizure Outcome ◽  
Malformation Of Cortical Development

Angiocentric Glioma: A Clinicopathologic Review of 5 Tumors With Identification of Associated Cortical Dysplasia

2011 ◽  
Vol 135 (8) ◽  
pp. 1037-1041 ◽  
Author(s):  
Trent Marburger ◽  
Richard Prayson
Keyword(s):  
Growth Pattern ◽  
Focal Cortical Dysplasia ◽  
Cortical Development ◽  
Temporal Cortex ◽  
Cortical Dysplasia ◽  
Low Grade ◽  
Type I ◽  
Clinicopathologic Features ◽  
Malformation Of Cortical Development ◽  
Angiocentric Glioma

Context.—Angiocentric glioma is a rare, epilepsy-associated, low-grade neoplasm with a characteristic perivascular growth pattern. Objective.—To describe the clinicopathologic features of 5 angiocentric gliomas and to evaluate for coexistent malformation of cortical development/cortical dysplasia. Design.—Retrospective review of the clinicopathologic features of 5 angiocentric gliomas (3 males and 2 females; median age at surgery, 10 years; range, 3–19 years). Results.—Seizures were the most common presenting symptom (n  =  4); 1 patient presented with headaches. Four of the tumors were located in the parieto-occipital, parietal, or temporal cortex and 1 case arose in the thalamus. All tumors consisted of an angiocentric growth pattern of bipolar spindle cells with mild pleomorphism. Three tumors also demonstrated a focal solid growth pattern. Evidence of adjacent malformation of cortical development/focal cortical dysplasia was observed in 4 of 4 cases with sufficient tissue for evaluation; all were Palmini et al type I lesions (type IA, n  =  1; type IB, n  =  3). All patients were alive at last known follow-up (17–131 months). Conclusions.—The thalamic location of 1 tumor represents an undescribed location for this typically superficial cortical tumor. A subset of angiocentric gliomas, similar to other low-grade chronic epilepsy-related tumors of childhood, are associated with coexistent malformation of cortical development, suggesting a developmental basis to their origin.

scholarly journals Applications of Intraoperative Ultrasound in Epilepsy Surgery for Focal Cortical Dysplasia

2014 ◽  
Vol 22 (1) ◽  
pp. 43-46 ◽  
Author(s):  
Cheng-Chia Lee ◽  
Chun-Fu Lin ◽  
Hsiang-Yu Yu ◽  
Sheng-Che Hung ◽  
Yang-Hsin Shih ◽  
...  
Keyword(s):  
Epilepsy Surgery ◽  
Focal Cortical Dysplasia ◽  
Intraoperative Ultrasound ◽  
Cortical Dysplasia

scholarly journals A case of mild malformation of cortical development with oligodendroglial hyperplasia and epilepsy (MOGHE)

2021 ◽  
Vol 12 (3) ◽  
pp. 93-100
Author(s):  
V. S. Khalilov ◽  
A. N. Kislyakov ◽  
T. V. Basalay ◽  
A. V. Levov ◽  
A. A. Kholin
Keyword(s):  
White Matter ◽  
Frontal Lobe ◽  
Focal Cortical Dysplasia ◽  
Epileptiform Activity ◽  
Cortical Development ◽  
Dynamic Mri ◽  
Subtotal Resection ◽  
Pharmacoresistant Epilepsy ◽  
Malformation Of Cortical Development ◽  
The Right

Recently, in the scientist community of specialists dealing with structural epilepsy, it has been noticed an increasing interest in a special form of cortical development disorder not to be included in the ILAE Classification of the epilepsies the 2017 revision. It is so-called mild malformation of cortical development with oligodendroglial hyperplasia and epilepsy (MOGHE). There are a number of publications devoted to the neuroimaging features of MOGHE, which are possible to distinguish from other epileptogenic substrates in comparisons with clinical/anamnestic data and dynamic observation. Our paper describes the case of a patient under 6 years suffering from pharmacoresistant epilepsy with histologically confirmed MOGHE, and having undergone the procedure of epileptic surgery. MRI showed an increased intensity of the T2/FLAIR signal from the white matter in combination with signs of laminar hyperintensivity, regional sulcation disturbance, smoothness of gray-white matter demarcation in the right frontal lobe. A signal intensification from the white matter with the formation similarity of the «transmantl» sign and further pronounced smoothness of the gray-white matter demarcation was observed on dynamic MRI. These changes were estimated as focal cortical dysplasia. Pre-surgical examination revealed a correlation of epileptiform activity with MRI changes. The subtotal resection of the right frontal lobe and the morphological conclusion established the presence of MOGHE was performed.

scholarly journals Coregistrating magnetic source and magnetic resonance imaging for epilepsy surgery in focal cortical dysplasia

2018 ◽  
Vol 19 ◽  
pp. 487-496 ◽  
Author(s):  
Burkhard S. Kasper ◽  
Karl Rössler ◽  
Hajo M. Hamer ◽  
Arnd Dörfler ◽  
Ingmar Blümcke ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Magnetic Resonance ◽  
Epilepsy Surgery ◽  
Focal Cortical Dysplasia ◽  
Cortical Dysplasia ◽  
Resonance Imaging ◽  
Magnetic Source

Epilepsies: Malformations of Cortical Development—Focal Cortical Dysplasia (FCD)

2019 ◽  
pp. 1157-1169
Author(s):  
Serge Weis ◽  
Michael Sonnberger ◽  
Andreas Dunzinger ◽  
Eva Voglmayr ◽  
Martin Aichholzer ◽  
...  
Keyword(s):  
Focal Cortical Dysplasia ◽  
Cortical Development ◽  
Cortical Dysplasia ◽  
Malformations Of Cortical Development

scholarly journals Outcome of epilepsy surgery in focal cortical dysplasia

2003 ◽  
Vol 74 (2) ◽  
pp. 183-188 ◽  
Author(s):  
T Kral ◽  
H Clusmann ◽  
I Blumcke ◽  
R Fimmers ◽  
B Ostertun ◽  
...  
Keyword(s):  
Epilepsy Surgery ◽  
Focal Cortical Dysplasia ◽  
Cortical Dysplasia
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