Antenatal Glucocorticoids Reduce the Incidence of Refractory Hypotension in Low Birthweight Infants during the Early Neonatal Period, but Do Not Affect It beyond This Time

Abstract Objective This study aimed to clarify the effect of antenatal glucocorticoids (AGs) on the incidence of refractory hypotension (RH) in very low birthweight (VLBW) infants after the first week of life. Study Design We included VLBW infants born at a gestational age of <30 weeks and divided them into three groups: the complete group (born within 7 days of completing a single course [two doses] of AGs), the incomplete group (born without complete course), and the late delivery group (born at ≥8 days after a single course). We compared the incidence and period of onset of RH among the three groups. Results A total of 115 infants were enrolled. The incidence of RH in the first week of life was significantly lower in the complete group than in the other groups. However, there was no significant difference in the incidence of RH after the first week of life among the groups. Conclusion AGs contribute to circulatory stabilization during the first week of life, but this effect does not last after 1 or 2 weeks of administration. In infants who receive AGs, physicians should consider that the risk of RH after the first week of life is not low.

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VERY LOW BIRTHWEIGHT (VLBW) INFANTS (<1000 G): INFLUENCE OF GESTATIONAL AGE (GA) AND INTRAUTERINE GROWTH RETARDATION ON THE INCIDENCE AND SEVERITY OF CEREBRAL ISCHEMIC-HAEMORRHAGIC LESIONS. A PROSPECTIVE STUDY

Pediatric Research ◽

10.1203/00006450-199402000-00048 ◽

1994 ◽

Vol 35 (2) ◽

pp. 262-262

Author(s):

O Claris ◽

A Lapillonne ◽

D Miguet ◽

B L Salle

Keyword(s):

Prospective Study ◽

Gestational Age ◽

Growth Retardation ◽

Intrauterine Growth Retardation ◽

Low Birthweight ◽

Very Low Birthweight ◽

Vlbw Infants ◽

Intrauterine Growth ◽

Cerebral Ischemic ◽

A Prospective Study

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1034 GLUCOSE INTOLERANCE IN VERY LOW BIRTHWEIGHT (VLBW) INFANTS

Pediatric Research ◽

10.1203/00006450-197804001-01040 ◽

1978 ◽

Vol 12 ◽

pp. 536-536

Author(s):

Yvonne E Vaucher ◽

Grant Morrow

Keyword(s):

Glucose Intolerance ◽

Low Birthweight ◽

Very Low Birthweight ◽

Vlbw Infants

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HOW TO PROLONG LACTATION IN MOTHERS OF VLBW INFANTS

PEDIATRICS ◽

10.1542/peds.83.5.a42a ◽

1989 ◽

Vol 83 (5) ◽

pp. A42-A42

Author(s):

Student

Keyword(s):

Developing Countries ◽

Low Birthweight ◽

Randomised Trial ◽

Control Group ◽

Very Low Birthweight ◽

Vlbw Infants ◽

Skin Contact ◽

Very Low Birthweight Infants ◽

Skin To Skin

We have carried out a randomised trial [of skin to skin contact with their mothers] among babies of less than 1500 gm . . . Mothers using skin to skin contact lactated for four weeks longer on average than the control group . . . [This maneuver] can enjoyably be offered to very low birthweight infants especially in developing countries where mother's lactation is vital.

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Longitudinal electrophysiological study of auditory pathway in small for gestational age infants

CoDAS ◽

10.1590/2317-1782/201420140042 ◽

2014 ◽

Vol 26 (4) ◽

pp. 294-301 ◽

Cited By ~ 2

Author(s):

Rosanna Giaffredo Angrisani ◽

Edna Maria Albuquerque Diniz ◽

Ruth Guinsburg ◽

Alexandre Archanjo Ferraro ◽

Marisa Frasson de Azevedo ◽

...

Keyword(s):

Gestational Age ◽

Small For Gestational Age ◽

Neonatal Period ◽

Electrophysiological Study ◽

Auditory Pathway ◽

Prospective Longitudinal Study ◽

The Third ◽

Significant Difference ◽

Brainstem Response ◽

Prospective Longitudinal

PURPOSE: To follow the maturation of the auditory pathway of infants born small for gestational age term, by studying absolute and interpeak latencies of Auditory Brainstem Response (ABR) in the first six months of life.METHODS: Multicentric prospective longitudinal study. The ABR was carried out in the neonatal period in 96 newborn infants, 49 small for gestational age (SGA) and 47 appropriate for gestational age (AGA). Of these, 77 infants (39 SGA and 38 AGA) returned for a second evaluation. In the third evaluation, 70 infants (35 SGA and 35 AGA) returned.RESULTS: SGA and AGA did not present significant differences in the neonatal period and at three months of life. However, at six months, there was statistical significant difference between SGA and AGA groups for the latencies of wave III and interpeak I-III. Latencies of ABR waves decreased more rapidly in the first three months than the third to the sixth month of life for the SGA. AGA group showed progressive decrease in latency of ABR waves during the six months.CONCLUSION: The findings suggest that, for SGA infants, the maturational process of the auditory pathway occurs in different rate when compared to AGA infants. The SGA infants have faster maturation especially at the first three months of life, while in infants AGA, this process occurred in a constant and gradual way throughout the six months studied.

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