Co/Ni Dual Catalysis: Accessing New Regioselectivity for the Ring Opening of Epoxides with Aryl Halides

Synfacts ◽  
2021 ◽  
Vol 17 (08) ◽  
pp. 0894
Keyword(s):  
Ring Opening ◽  
Aryl Halides ◽  
Ring Opening Of Epoxides ◽  
Dual Catalysis

scholarly journals Cobalt Catalysis Enables Regioselective Ring-opening of Epoxides with Aryl Halides

2021 ◽  
Author(s):  
Aleksandra Potrząsaj ◽  
Mateusz Musiejuk ◽  
Wojciech Chaładaj ◽  
Maciej Giedyk ◽  
Dorota Gryko
Keyword(s):  
Vitamin B12 ◽  
Organic Synthesis ◽  
Blue Light ◽  
Catalytic System ◽  
Ring Opening ◽  
Aryl Halides ◽  
Light Irradiation ◽  
Selective Synthesis ◽  
Ring Opening Of Epoxides

Ring-opening of epoxides furnishing either linear or branched products belongs to the group of classic transformations in organic synthesis. However, the regioselective cross-electrophile coupling of aryl epoxides with aryl halides still represents a key challenge. Herein, we report vitamin B12/Ni dual-catalytic system that allows for the selective synthesis of linear products under blue-light irradiation.

scholarly journals Cobalt Catalysis Enables Regioselective Ring-opening of Epoxides with Aryl Halides

2021 ◽  
Author(s):  
Aleksandra Potrząsaj ◽  
Mateusz Musiejuk ◽  
Wojciech Chaładaj ◽  
Maciej Giedyk ◽  
Dorota Gryko
Keyword(s):  
Vitamin B12 ◽  
Organic Synthesis ◽  
Blue Light ◽  
Catalytic System ◽  
Ring Opening ◽  
Aryl Halides ◽  
Light Irradiation ◽  
Selective Synthesis ◽  
Ring Opening Of Epoxides

Ring-opening of epoxides furnishing either linear or branched products belongs to the group of classic transformations in organic synthesis. However, the regioselective cross-electrophile coupling of aryl epoxides with aryl halides still represents a key challenge. Herein, we report vitamin B12/Ni dual-catalytic system that allows for the selective synthesis of linear products under blue-light irradiation.

scholarly journals Cobalt Catalyst Determines Regioselectivity in Ring Opening of Epoxides with Aryl Halides

2021 ◽  
Author(s):  
Aleksandra Potrząsaj ◽  
Mateusz Musiejuk ◽  
Wojciech Chaładaj ◽  
Maciej Giedyk ◽  
Dorota Gryko
Keyword(s):  
Ring Opening ◽  
Cobalt Catalyst ◽  
Aryl Halides ◽  
Ring Opening Of Epoxides

scholarly journals Environmentally benign and highly regioselective ring opening of epoxides accelerated by ultrasound irradiation

2016 ◽  
Vol 9 (1) ◽  
pp. 76-84 ◽  
Author(s):  
Mohamed Mahmoud Nasef ◽  
Masoumeh Zakeri ◽  
Jahanbakhsh Asadi ◽  
Ebrahim Abouzari-Lotf ◽  
Arshad Ahmad ◽  
...  
Keyword(s):  
Ring Opening ◽  
Ultrasound Irradiation ◽  
Environmentally Benign ◽  
Ring Opening Of Epoxides

Borates as a Traceless Activation Group for Intermolecular Alkylarylation of Ethylene through Photoredox/Nickel Dual Catalysis

Synlett ◽  
2020 ◽  
Author(s):  
Shengqing Zhu ◽  
Lingling Chu ◽  
Xiaoliang Feng ◽  
Lei Guo
Keyword(s):  
Functional Groups ◽  
Aryl Halides ◽  
Nickel Catalysis ◽  
Mild Conditions ◽  
Dual Catalysis

AbstractA formal ethylene alkylarylation reaction with aryl halides and alkyl oxalates enabled by synergistic photoredox/nickel catalysis is reported. This protocol takes advantage of borates as a traceless activation group, achieving the formal ethylene difunctionalized products via a catalytic three-component 1,2-alkylarylation of vinyl borate followed by a base-assisted deborylation process. The mild conditions allow for excellent functional groups compatibility and broad substrate scope.

Sign in / Sign up

Export Citation Format

Share Document