Advances in Oromandibular Reconstruction with Three-Dimensional Printing

AbstractThe mandibular structures are a complex anatomical structure that is fundamental to many physiological and homeostatic functions. It may be involved in many pathological processes that require partial or complete removal. When this happens, reconstruction is mandatory to improve cosmetic outcome with its effect on social interaction as well as to provide an opportunity for complete dental rehabilitation with restoration of all physiological functions. This article will review the different reconstructive options available for complex defects of the mandibular complex. It will highlight the surgical options available to maximize functional restoration. Finally, it will discuss computer modeling to optimize reconstructive planning.

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The power of three-dimensional printing technology in functional restoration of rare maxillomandibular deformity due to genetic disorder: a case report

Journal of Medical Case Reports ◽

10.1186/s13256-021-02741-5 ◽

2021 ◽

Vol 15 (1) ◽

Author(s):

Daniel Oren ◽

Amiel A. Dror ◽

Tania Bramnik ◽

Eyal Sela ◽

Igal Granot ◽

...

Keyword(s):

Genetic Disorder ◽

Three Dimensional ◽

Thalassemia Major ◽

Functional Restoration ◽

Beta Thalassemia ◽

Blood Transfusions ◽

Printing Technology ◽

Three Dimensional Printing ◽

Beta Thalassemia Major ◽

Dimensional Printing

Abstract Background Thalassemia is an inherited autosomal recessive blood disorder causing abnormal formation of hemoglobin, known as a syndrome of anemia with microcytic erythrocytes. It is the most common genetic disorder worldwide, with a high prevalence among individuals of Mediterranean descent. The state of homozygosity of the beta-globin mutated gene is known as beta-thalassemia major, and these patients require regular blood transfusions and iron chelation therapy for survival. The rapid loss of red blood cells among affected individuals activates compensatory mechanisms of excessive medullary and extramedullary hematopoiesis, leading to severe skeletal bone deformity. Case presentation We present the case of a 39-year-old Bedouin male, diagnosed with beta-thalassemia major at infancy, with diagnosed homozygosity for the intervening sequence 2-1 (guanine > adenine) mutation. Since early infancy, he started receiving blood transfusions with a gradual increase in treatment frequency through adulthood due to the severe clinical progression of the disease. He was referred to the oral and maxillofacial surgery department at Galilee Medical Center to evaluate his facial deformity in the upper jaw and treat his severe periodontal disease. The patient presented maxillary overgrowth, and severe dental deformity resulted in progressive disfigurement and difficulty chewing, swallowing, and speaking. To address the challenge of surgical treatment, we utilized the advantage of three-dimensional planning and printing technology to simulate the optimal result. Resection of maxillary bone overgrowth and insertion of custom-made subperiosteal implants were followed by rehabilitation of both jaws to the patients' satisfaction at 3-year follow-up. Conclusions The ongoing implementation of state-of-the-art technologies such as virtual reality and three-dimensional printing has become a prominent component in surgical toolsets. Comprehensive case simulation and accurate planning before surgery will improve surgical results and patient satisfaction. This approach is highly advocated when approaching a case of rare maxillofacial deformity associated with either genetic or orphan diseases.

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Reconstruction of the Midface and Palate

Seminars in Plastic Surgery ◽

10.1055/s-0040-1709470 ◽

2020 ◽

Vol 34 (02) ◽

pp. 077-085

Author(s):

Adam Bender-Heine ◽

Mark K. Wax

Keyword(s):

Social Interaction ◽

Computer Modeling ◽

Complete Removal ◽

Functional Restoration ◽

Cosmetic Outcome ◽

Anatomic Structure ◽

Surgical Options ◽

Pathologic Processes

AbstractThe midface is a complex anatomic structure that is fundamental to many physiologic and homeostatic functions. It may be involved in many pathologic processes that require partial or complete removal. When this happens, reconstruction is mandatory to improve cosmetic outcome with its effect on social interaction as well as to provide an opportunity for complete orodental rehabilitation with restoration of all physiologic functions. This article will review the different reconstructive options available for complex defects of the maxillofacial complex. It will highlight the surgical options available to maximize functional restoration. Finally, it will discuss computer modeling to optimize reconstructive planning.

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Jaw in a Day: Immediate Dental Rehabilitation during Fibula Reconstruction of the Mandible

Facial Plastic Surgery ◽

10.1055/s-0041-1732478 ◽

2021 ◽

Author(s):

Adrian Ong ◽

Fayette Williams ◽

Ellen Tokarz ◽

Tom Shokri ◽

Daniel Hammer ◽

...

Keyword(s):

Dental Implants ◽

Three Dimensional ◽

Free Flaps ◽

Virtual Technology ◽

Three Dimensional Printing ◽

Surgical Workflow ◽

Jaw Reconstruction ◽

Dental Prostheses ◽

Dental Rehabilitation ◽

Dimensional Printing

AbstractReconstructing mandibular defects presents challenges to dental rehabilitation related to altered bone and soft tissue anatomy. Dental implants are the most reliable method to restore the lost dentition. Immediate dental implants have been placed for many years but with unacceptably low rates of dental/prosthetic success. Current virtual technology allows placement of both fibulas and guided implants in restoratively driven positions that also allow immediate dental rehabilitation. Inexpensive three-dimensional printing platforms can create provisional dental prostheses placed at the time of surgery. This article reviews our digital and surgical workflow to create an immediate dental prosthesis to predictably restore the dentition during major jaw reconstruction with fibula free flaps.

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A novel fast disintegrating tablet fabricated by three‐dimensional printing

Drug Development and Industrial Pharmacy ◽

10.1080/03639040903059359 ◽

2009 ◽

Vol 00 (00) ◽

pp. 090730035508060-7

Author(s):

Deng-Guang Yu ◽

Chris Branford-White ◽

Yi-Cheng Yang ◽

Li-Min Zhu ◽

Edward William Welbeck ◽

...

Keyword(s):

Three Dimensional ◽

Three Dimensional Printing ◽

Fast Disintegrating Tablet ◽

Dimensional Printing

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Faculty Opinions recommendation of Development and initial porcine and cadaver experience with three-dimensional printing of endoscopic and laparoscopic equipment.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.718475764.793516604 ◽

2016 ◽

Author(s):

Mitchell Humphreys

Keyword(s):

Three Dimensional ◽

Three Dimensional Printing ◽

Laparoscopic Equipment ◽

Dimensional Printing

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Central ossifying fibroma of mandible

BMJ Case Reports ◽

10.1136/bcr-2020-239286 ◽

2020 ◽

Vol 13 (12) ◽

pp. e239286

Author(s):

Kumar Nilesh ◽

Prashant Punde ◽

Nitin Shivajirao Patil ◽

Amol Gautam

Keyword(s):

Fibrous Tissue ◽

Three Dimensional ◽

Facial Asymmetry ◽

Ossifying Fibroma ◽

Mandible Reconstruction ◽

Three Dimensional Printing ◽

Osseous Lesion ◽

Large Size ◽

Dimensional Printing

Ossifying fibroma (OF) is a rare, benign, fibro-osseous lesion of the jawbone characterised by replacement of the normal bone with fibrous tissue. The fibrous tissue shows varying amount of calcified structures resembling bone and/or cementum. The central variant of OF is rare, and shows predilection for mandible among the jawbone. Although it is classified as fibro-osseous lesion, it clinically behaves as a benign tumour and can grow to large size, causing bony swelling and facial asymmetry. This paper reports a case of large central OF of mandible in a 40-year-old male patient. The lesion was treated by segmental resection of mandible. Reconstruction of the surgical defect was done using avascular fibula bone graft. Role of three-dimensional printing of jaw and its benefits in surgical planning and reconstruction are also highlighted.

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