scholarly journals Refractory Pulmonary Interstitial Emphysema in Extreme Premature Newborn

2021 ◽  
Vol 11 (02) ◽  
pp. e61-e64
Author(s):  
Mahmoud Ali ◽  
Lea Mallett ◽  
Greg Miller

AbstractPulmonary interstitial emphysema (PIE) occurs when air leaks into the pulmonary interstitium due to overdistension of distal airways, it occurs mainly in neonates with respiratory distress syndrome who need positive pressure ventilation but has also been reported in spontaneously breathing infants. Herein, we report on an extremely low birth weight infant with severe persistent PIE, while on invasive mechanical ventilation (high-frequency oscillatory ventilation, high-frequency jet ventilation, and neurally adjust ventilator assist) managed successfully with 2 weeks of selective right lung ventilation after failure of more conservative measures, including shorter periods of right mainstem intubation, before the prolonged trial that was successful.

PEDIATRICS ◽  
1987 ◽  
Vol 79 (1) ◽  
pp. 162-164
Author(s):  
THOMAS E. WISWELL ◽  
REESE H. CLARK ◽  
J. DEVN CORNISH

To the Editor.— We read with interest the study of Mammel et al.1 However, we wish to address several aspects of the report regarding the design of the investigation, their interpretation of the results and of other reports, and the conclusions they make. First, we take exception to the title itself. Unfortunately, many pediatricians and neonatologists do not make any distinction between the various types of nonconventional, high-frequency ventilators. High-frequency ventilation is a generic term encompassing several very different modalities of ventilation including high-frequency positive pressure ventilation, high-frequency flow interruption, high-frequency jet ventilation, and high-frequency oscillatory ventilation.


1996 ◽  
Vol 89 (3) ◽  
pp. 167P-168P
Author(s):  
J S Ahluwalia ◽  
J M Rennie ◽  
F C Wells

Extubation of ventilated infants with severe unilateral pulmonary interstitial emphysema is difficult because the function of normal lung tissue is impaired. Continued positive pressure ventilation worsens hyperinflation on the side with interstitial emphysema, leading to cardiorespiratory compromise. Resection of affected single lobes is well described, but there are no reported cases of multiple lobectomies in very low birthweight infants. We describe a case where resection of both right upper and middle lobes was successful, allowing extubation within a few days of surgery. Computed tomography (CT) of the chest was helpful in making the decision to treat this infant by surgery.


PEDIATRICS ◽  
1996 ◽  
Vol 97 (3) ◽  
pp. 437-438
Author(s):  
MICHAEL S. PARANKA ◽  
REESE H. CLARK

We appreciate the observation reported by Cheung et al, and agree with their findings. We reported similar results on survival in premature infants with pulmonary interstitial emphysema in 1986. These data show that high-frequency oscillatory ventilation (HFOV) response delineates two groups of infants with different outcomes. It is important to note that most neonates treated with HFOV have improved ventilation, but that a smaller proportion of neonates have improved oxygenation. In our experience improved oxygenation is a better predictor of outcome than improved ventilation.


1986 ◽  
Vol 14 (11) ◽  
pp. 926-930 ◽  
Author(s):  
REESE H. CLARK ◽  
DALE R. GERSTMANN ◽  
DONALD M. NULL ◽  
BRADLEY A. YODER ◽  
J. DEVN CORNISH ◽  
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