scholarly journals Double endoscopic bypass for gastric outlet obstruction and biliary obstruction

2017 ◽  
Vol 05 (09) ◽  
pp. E893-E899 ◽  
Author(s):  
Olaya Brewer Gutierrez ◽  
Jose Nieto ◽  
Shayan Irani ◽  
Theodore James ◽  
Renata Pieratti Bueno ◽  
...  
Keyword(s):  
Adverse Events ◽  
Biliary Obstruction ◽  
Primary Outcome ◽  
Clinical Success ◽  
Outlet Obstruction ◽  
Pancreatic Head ◽  
Oral Intake ◽  
Head Cancer ◽  
Pancreatic Head Cancer ◽  
Novel Concept

Abstract Background and study aims Double endoscopic bypass entails EUS-guided gastroenterostomy (EUS-GE) and EUS-guided biliary drainage (EUS-BD) in patients who present with gastric outlet and biliary obstruction. We report a multicenter experience with double endoscopic bypass. Patients and methods Retrospective, multicenter series involving 3 US centers. Patients who underwent double endoscopic bypass for malignant gastric and biliary obstruction from 1/2015 to 12/2016 were included. Primary outcome was clinical success defined as tolerance of oral intake and resolution of cholestasis. Secondary outcomes included technical success, re-interventions and adverse events (AE). Results Seven patients with pancreatic head cancer (57.1 % females; mean age 64.6 ± 12.5 years) underwent double endoscopic bypass. Four patients had EUS-GE and EUS-BD performed during the same session with a mean procedure time of 70 ± 20.4 minutes. EUS-GE and EUS-BD were technically successful in all patients, all of whom were able to tolerate oral intake with resolution of cholestasis in 6 (87.5 %). One patient had a repeat EUS-BD with normalization of bilirubin. There were no adverse events. Conclusions Double endoscopic bypass is feasible and effective when performed by experienced operators. Studies comparing this novel concept to existing techniques are warranted.

Clinical impact of preoperative tumour contact with superior mesenteric-portal vein in patients with resectable pancreatic head cancer

2021 ◽  
Author(s):  
Fabio Ausania ◽  
Santiago Sanchez-Cabus ◽  
Paula Senra del Rio ◽  
Alex Borin ◽  
Juan Ramon Ayuso ◽  
...  
Keyword(s):  
Portal Vein ◽  
Pancreatic Head ◽  
Clinical Impact ◽  
Head Cancer ◽  
Pancreatic Head Cancer

Percutaneous Palliation of Pancreatic Head Cancer: Randomized Comparison of ePTFE/FEP–Covered Versus Uncovered Nitinol Biliary Stents

2010 ◽  
Vol 34 (2) ◽  
pp. 352-361 ◽  
Author(s):  
Miltiadis Krokidis ◽  
Fabrizio Fanelli ◽  
Gianluigi Orgera ◽  
Dimitrios Tsetis ◽  
Ioannis Mouzas ◽  
...  
Keyword(s):  
Pancreatic Head ◽  
Biliary Stents ◽  
Head Cancer ◽  
Pancreatic Head Cancer

Embolization of the Replaced Common Hepatic Artery Before Surgery for Pancreatic Head Cancer: Report of a Case

Surgery Today ◽  
2004 ◽  
Vol 34 (7) ◽  
Author(s):  
Noriyuki Miyamoto ◽  
Yoshihisa Kodama ◽  
Hideho Endo ◽  
Tadashi Shimizu ◽  
Kazuo Miyasaka ◽  
...  
Keyword(s):  
Hepatic Artery ◽  
Pancreatic Head ◽  
Common Hepatic Artery ◽  
Head Cancer ◽  
Pancreatic Head Cancer ◽  
Replaced Common Hepatic Artery

scholarly journals Total mesopancreas excision for the treatment of pancreatic head cancer

2017 ◽  
Vol 8 (17) ◽  
pp. 3575-3584 ◽  
Author(s):  
Jingyong Xu ◽  
Xiaodong Tian ◽  
Yiran Chen ◽  
Yongsu Ma ◽  
Chang Liu ◽  
...  
Keyword(s):  
Pancreatic Head ◽  
Head Cancer ◽  
Pancreatic Head Cancer

scholarly journals Comparative Bioinformatical Analysis of Pancreatic Head Cancer and Pancreatic Body/Tail Cancer

HPB ◽  
2021 ◽  
Vol 23 ◽  
pp. S54
Author(s):  
L. Yin ◽  
L. Xiao ◽  
Y. Gao ◽  
G. Wang ◽  
H. Gao ◽  
...  
Keyword(s):  
Pancreatic Head ◽  
Head Cancer ◽  
Pancreatic Head Cancer ◽  
Pancreatic Body ◽  
Bioinformatical Analysis

scholarly journals Management and Reconstruction of a Gastroesophageal Junction Adenocarcinoma Patient Three Years after Pancreaticoduodenectomy: A Surgical Puzzle

2016 ◽  
Vol 2016 ◽  
pp. 1-3 ◽  
Author(s):  
Dionysios Dellaportas ◽  
James A. Gossage ◽  
Andrew R. Davies
Keyword(s):  
Gastroesophageal Junction ◽  
Pancreatic Head ◽  
Second Primary ◽  
Primary Cancer ◽  
Head Cancer ◽  
Gastrointestinal Malignancies ◽  
Pancreatic Head Cancer ◽  
Gastroesophageal Junction Adenocarcinoma ◽  
Gastrointestinal Reconstruction ◽  
Gastroesophageal Adenocarcinoma

Introduction. With the improving survival of cancer patients, the development of a secondary primary cancer is an increasingly common phenomenon. Extensive surgery during initial treatment may pose significant challenges to surgeons managing the second primary cancer.Case Presentation. A 69-year-old male, who had a pancreaticoduodenectomy three years ago for pancreatic head adenocarcinoma, underwent an uneventful extended total gastrectomy for gastroesophageal junctional adenocarcinoma. The reconstruction controversies and considerations are highlighted.Discussion. Genetic, environmental, and lifestyle factors are common for several gastrointestinal malignancies. However, the occurrence of a second unfavorable cancer such as gastroesophageal adenocarcinoma after pancreatic head cancer treatment is extremely uncommon. This clinical scenario possesses numerous difficulties for the surgeon, since surgical resection is the mainstay of treatment for both malignancies. Gastrointestinal reconstruction becomes challenging and requires careful planning and meticulous surgical technique along with sound intraoperative judgement.

Results of complex treatment of patients with operable pancreatic head cancer using preoperative intra-arterial chemotherapy in combination with radiation therapy in multifractionation mode

2022 ◽  
pp. 32-36
Author(s):  
D. A. Sklyar ◽  
A. V. Pavlovsky ◽  
A. A. Polikarpov ◽  
S. A. Popov ◽  
V. E. Moiseenko ◽  
...  
Keyword(s):  
Radiation Therapy ◽  
Pancreatic Head ◽  
Main Group ◽  
Arterial Infusion ◽  
Conformal Radiation Therapy ◽  
Head Cancer ◽  
Pancreatic Head Cancer ◽  
Postoperative Pancreatitis ◽  
Pancreatic Fistulas ◽  
And Control

The aim of this study was to assess the safety and efficacy of treating patients with operable pancreatic cancer after preoperative intra-arterial infusion of chemotherapy combined with conformal radiation therapy in a multi-fractionation mode. Patients (n = 40) were randomized into two groups: the main one – intra-arterial infusion of chemotherapy + radiation therapy + surgery (n = 20), and control – intra-arterial infusion of chemotherapy + surgery (n = 20). Neoadjuvant therapy consisted of intra-arterial infusion of chemotherapy (chemoembolization of a pancreatic head tumor with oxaliplatin 85 mg/m2) followed by intra-arterial chemo infusion with gemcitabine 1000 mg/m2. In the main group, radiation therapy was also carried out in two fractions per day, 2 Gy with an interval of 4–6 hours, 5 days a week, up to a total dose of 50 Gy. In the main group, the lower incidence of postoperative pancreatitis and the pancreatic fistulas were statistically confirmed, the incidence of grade 2 therapeutic pathomorphisis increased, as well as the median life expectancy.

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