Quality of Life in Patients with Advanced Gastric Cancer Treated with Second-Line Chemotherapy

Endoscopy ◽  
2006 ◽  
Vol 38 (10) ◽  
Author(s):  
P Heras ◽  
A Hatzopoulos
Keyword(s):  
Quality Of Life ◽  
Gastric Cancer ◽  
Advanced Gastric Cancer ◽  
Second Line ◽  
Second Line Chemotherapy ◽  
Line Chemotherapy

Quality of life in patients with advanced gastric cancer treated with second-line chemotherapy

2005 ◽  
Vol 57 (3) ◽  
pp. 289-294 ◽  
Author(s):  
Se Hoon Park ◽  
Woon Ki Lee ◽  
Min Chung ◽  
Soo-Mee Bang ◽  
Eun Kyung Cho ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Gastric Cancer ◽  
Advanced Gastric Cancer ◽  
Second Line ◽  
Second Line Chemotherapy ◽  
Line Chemotherapy

A clinical study of docetaxel with or without 5′DFUR as a second-line chemotherapy for advanced gastric cancer

2007 ◽  
Vol 24 (1) ◽  
pp. 71-75 ◽  
Author(s):  
Fukuto Maruta ◽  
Satoshi Ishizone ◽  
Manabu Hiraguri ◽  
Yoshiro Fujimori ◽  
Fumiaki Shimizu ◽  
...  
Keyword(s):  
Gastric Cancer ◽  
Clinical Study ◽  
Advanced Gastric Cancer ◽  
Second Line ◽  
Second Line Chemotherapy ◽  
Line Chemotherapy

scholarly journals Modified FOLFIRI as Second-Line Chemotherapy after Failure of Modified FOLFOX-4 in Advanced Gastric Cancer

2011 ◽  
Vol 43 (3) ◽  
pp. 148-153 ◽  
Author(s):  
Eun Kyoung Jeon ◽  
Sook Hee Hong ◽  
Tae Hee Kim ◽  
Seung Eun Jung ◽  
Ji Chan Park ◽  
...  
Keyword(s):  
Gastric Cancer ◽  
Advanced Gastric Cancer ◽  
Second Line ◽  
Second Line Chemotherapy ◽  
Line Chemotherapy

scholarly journals Efficacy of Acupuncture and Moxibustion as a Subsequent Treatment after Second-Line Chemotherapy in Advanced Gastric Cancer

2020 ◽  
Vol 2020 ◽  
pp. 1-9
Author(s):  
Yong-jie Zhang ◽  
Qi Min ◽  
Ying Huang ◽  
Huai-dong Liu ◽  
Zi-yuan Zhu ◽  
...  
Keyword(s):  
Gastric Cancer ◽  
Advanced Gastric Cancer ◽  
Cancer Patients ◽  
Plasma Levels ◽  
Mrna Levels ◽  
Second Line ◽  
Second Line Chemotherapy ◽  
Acupuncture And Moxibustion ◽  
Gastric Cancer Patients ◽  
Line Chemotherapy

Objective. To explore whether acupuncture and moxibustion can prevent disease progression of advanced gastric cancer patients completing second-line chemotherapy and, if so, the related mechanism. Method. Progression-free survival (PFS) and overall survival (OS) were main outcome measures. The real-time quantitative PCR was used to detect the expression of genes including T-bet, IFN-γ, GATA3, and IL-4 in peripheral blood mononuclear cells (PBMCs). IL-4, IL-6, Ca199, CRP, and IFN-γ in plasma levels were checked. Results. 170 patients were randomly assigned in a 3 : 2 ratio to receive either acupuncture and moxibustion or sham acupuncture until progression. 135 patients were included in the primary analysis. Both PFS and OS in treatment group were proven to be better than control group. Acupuncture and moxibustion promoted typical Th1 cells drifting, as confirmed by increased T-bet/IFN-γ and decreased GATA3/IL-4 in mRNA levels from PBMCs, as well as upregulating IFN-γ and downregulating IL-4 in plasma levels. IL-6, Ca199, and CRP in plasma levels were also reduced by acupuncture and moxibustion. Conclusions. Acupuncture and moxibustion can prolong PFS and OS of advanced gastric cancer patients completing second-line chemotherapy by reversing Th1/Th2 shift and attenuating inflammatory responses.

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