Management of Pregnancy after Radical Trachelectomy: Case Reports and Systematic Review of the Literature

Background. The risks of occupational asthma (OA) from antibiotics are uncertain. We report 4 new cases and a systematic review of the literature. Methods. Cases were identified through a specialist clinic, each underwent specific provocation testing (SPT). We subsequently reviewed the published literature. Results. The patients were employed in the manufacture of antibiotics; penicillins were implicated in three cases, in the fourth erythromycin, not previously reported to cause OA. In two, there was evidence of specific IgE sensitisation. At SPT each developed a late asthmatic reaction and increased bronchial hyperresponsiveness. 36 case reports have been previously published, 26 (citing penicillins or cephalosporins). Seven cross-sectional workplace-based surveys found prevalences of 5–8%. Conclusions. OA in antibiotic manufacturers may be more common than is generally recognised. Its pathogenesis remains unclear; immunological tests are of uncertain value and potential cases require confirmation with SPT. Further study of its frequency, mechanisms, and diagnosis is required.

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Grisel’s Syndrome in Children: Two Case Reports and Systematic Review of the Literature

Case Reports in Pediatrics ◽

10.1155/2020/8819758 ◽

2020 ◽

Vol 2020 ◽

pp. 1-11

Author(s):

Nicole Pini ◽

Martina Ceccoli ◽

Patrizia Bergonzini ◽

Lorenzo Iughetti

Keyword(s):

Systematic Review ◽

Surgical Treatment ◽

Conservative Treatment ◽

Early Diagnosis ◽

Head And Neck ◽

Case Reports ◽

Atlantoaxial Joint ◽

Review Of The Literature ◽

Grisel’S Syndrome

Background and Objective. Grisel’s syndrome is a rare syndrome characterized by nontraumatic rotatory subluxation of the atlantoaxial joint. It usually affects children and typically presents with torticollis after ear, nose, and throat (ENT) surgery or head and neck infections. In the pediatric literature, there is only a small amount of available data; moreover, no systematic review has been previously done with focus on the pediatric population. We report our experience of two cases, and we provide a systematic review on Grisel’s syndrome in children in order to offer a deeper insight about its clinical presentation, its current diagnosis, and principles of treatment. Case Reports and Review. We describe two boys of 9 and 8 years old, who developed atlantoaxial subluxation after adenoidectomy. Considering the early diagnosis, a conservative treatment was chosen, with no recurrence and no sequelae at follow-up. We identified 114 case reports, of which 90 describe children, for a total of 171 pediatric patients. Of the 154 cases in which cause was reported, 59.7% presented a head and neck infection and 35.7% had previous head and neck surgery. There is no sex prevalence (49.7% males versus 50.2% females). Mean delay in diagnosis is 33 days. Eight % of the patients had neurological impairment of the 165 cases which mentioned treatment, 96% underwent a conservative treatment, of whom the 8.8% recurred with the need of surgery. As a whole, 12% underwent surgery as a first- or second-line treatment. 3 6% of the patients whose follow-up was reported developed a sequela, minor limitation of neck movement being the most frequent. Conclusion. Grisel’s syndrome should be suspected in children with painful unresponsive torticollis following ENT procedures or head and neck inflammation. CT scan with 3D reconstruction is the gold standard for diagnosis, allowing the identification of the subluxation and the classification according to the Fielding–Hawkins grading system. Surgical treatment is indicated in case of high-grade instability or failure of conservative treatment. Review of the literature shows how early diagnosis based on clinical and radiological evaluation is crucial in order to avoid surgical treatment and neurologic sequelae.

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Abdominal radical trachelectomy during pregnancy: A systematic review of the literature

Journal of Gynecology Obstetrics and Human Reproduction ◽

10.1016/j.jogoh.2019.07.003 ◽

2020 ◽

Vol 49 (2) ◽

pp. 101607 ◽

Cited By ~ 1

Author(s):

Athanasios Douligeris ◽

Anastasia Prodromidou ◽

Victoria Psomiadou ◽

Christos Iavazzo ◽

George Vorgias

Keyword(s):

Systematic Review ◽

Review Of The Literature ◽

Radical Trachelectomy

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Spatio-temporal dynamics of interictal activity in musicogenic epilepsy: Two case reports and a systematic review of the literature

Clinical Neurophysiology ◽

10.1016/j.clinph.2020.06.028 ◽

2020 ◽

Vol 131 (10) ◽

pp. 2393-2401

Author(s):

Arturo Nuara ◽

Laura Mirandola ◽

Maddalena Fabbri-Destro ◽

Giada Giovannini ◽

Giovanni Vecchiato ◽

...

Keyword(s):

Systematic Review ◽

Temporal Dynamics ◽

Case Reports ◽

Review Of The Literature ◽

Spatio Temporal ◽

Musicogenic Epilepsy

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Thrombotic microangiopathy in the course of catastrophic antiphospholipid syndrome successfully treated with eculizumab: case report and systematic review of the literature

Lupus ◽

10.1177/0961203320917460 ◽

2020 ◽

Vol 29 (6) ◽

pp. 631-639 ◽

Cited By ~ 1

Author(s):

Marta Skoczynska ◽

Mark A Crowther ◽

Malgorzata Chowaniec ◽

Monika Ponikowska ◽

Shruti Chaturvedi ◽

...

Keyword(s):

Systematic Review ◽

Case Report ◽

Antiphospholipid Syndrome ◽

Lupus Erythematosus ◽

Single Case ◽

Case Reports ◽

Review Of The Literature ◽

Catastrophic Antiphospholipid Syndrome ◽

Total Remission

Objective The purpose of this study was to characterize the role of eculizumab, a monoclonal antibody against the terminal complement component C5, in patients with catastrophic antiphospholipid syndrome (CAPS). Methods We present a case report of a patient with systemic lupus erythematosus (SLE) and CAPS treated with eculizumab, as well as results of a systematic review of the literature. Results Including our patient, we identified 11 case reports of patients with CAPS treated with eculizumab. All of them had partial or total remission of symptoms. Conclusion Data on eculizumab efficacy in CAPS are promising but are limited to single case reports. More studies are needed to develop evidence-based recommendations for eculizumab use in CAPS.

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Evidence for the Efficacy of Scrambler Therapy for Cancer Pain: A Systematic Review

January 2018 - Pain Physician ◽

10.36076/ppj.2020/23/349 ◽

2020 ◽

Vol 4;23 (7;4) ◽

pp. 349-363

Author(s):

Sushma Bhatnagar

Keyword(s):

Systematic Review ◽

Cancer Pain ◽

Pain Treatment ◽

Case Reports ◽

Effective Therapy ◽

Reference List ◽

Review Of The Literature ◽

Meta Review ◽

Literature Reviews ◽

Scrambler Therapy

Background: Certain types of cancer pain have remained hard to control even by highly skilled pain experts. Uncontrolled cancer pain can have severe effects on quality of life, physical functioning, and leads to psychological distress. From this perspective, nonpharmacologic modalities of treatment are important. Neuromodulatory techniques, such as transcutaneous electrical nerve stimulation and scrambler therapy (ST), have gained popularity in recent times. ST is a relatively new therapy that has been used for the management of cancer pain resistant to pharmacologic management. Several studies have shown that ST is an effective therapy for this type of pain. Objectives: The aim of this study was to detect possible gaps in the literature regarding the efficacy of ST for cancer pain and formulate recommendations for research through a systematic review of the literature. Study Design: A systematic review of the literature was performed following the recommendations of the PRISMA Statement. Methods: PubMed and EMBASE were searched for studies that met the inclusion criteria using a predetermined search strategy. Reference list of retrieved studies and Google Scholar were used to verify that no relevant studies had been omitted. Data were extracted from the studies with a data extraction sheet. A qualitative analyses of the extracted data was undertaken. Results: Twenty-seven studies were retrieved. Ten were articles that were categorized as literature reviews, including 7 general literature reviews not following a specific review methodology, 1 editorial, and 2 systematic reviews. Seventeen were original studies, including 2 single-arm trials, 1 randomized controlled trial, 4 pilot trials, 4 case reports, 2 retrospective studies, and 4 prospective studies. By and large, the available literature supports the use of ST as an effective therapy for the management of refractory cancer pain. However, the level of evidence for its application to cancer pain is not particularly strong, and improvement in pain with ST may even be owing to a placebo effect. Limitations: This study was not a meta-review. Because of the limited number of clinical trials on ST in cancer pain, such a meta-review could not meaningfully be performed. Conclusions: Methodologically sound, large randomized control trials are needed in this area. However at this stage, ST may be considered a good option for cancer patients suffering from pain that does not respond to pharmacologic treatment. Key words: Scrambler therapy, cancer, cancer pain, neuropathic pain, Calmare therapy, evidence, noninvasive pain treatment, chronic pain

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Cavernous Malformations of the Optic Nerve and Optic Pathway: A Case Series and Systematic Review of the Literature

Operative Neurosurgery ◽

10.1093/ons/opab284 ◽

2021 ◽

Author(s):

Visish M Srinivasan ◽

Stefan W Koester ◽

Michele S Wang ◽

Redi Rahmani ◽

Kevin L Ma ◽

...

Keyword(s):

Systematic Review ◽

Optic Nerve ◽

Single Case ◽

Case Reports ◽

Case Series ◽

Senior Author ◽

Optic Pathway ◽

Review Of The Literature ◽

Cavernous Malformations ◽

Single Center Experience

Abstract BACKGROUND Although rare, cavernous malformations (CMs) of the optic nerve and anterior optic pathway (optic pathway cavernous malformations [OPCMs]) can occur, as described in several single case reports in the literature. OBJECTIVE To describe the technical aspects of microsurgical management of CMs of the optic pathway on the basis of an extensive single-center experience and review of the literature. METHODS A systematic literature review was performed to augment an earlier review, using PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) guidelines. In addition, an institutional database was searched for all patients undergoing surgical resection of OPCMs. Patient information, surgical technique, and clinical and radiographic outcomes were assessed. RESULTS Since the previous report, 14 CMs were resected at this institution or by the senior author at another institution. In addition, 34 cases were identified in the literature since the systematic review in 2015, including some earlier cases that were not discussed in the previous report. Most OPCMs were resected via pterional, orbital-pterional, and orbitozygomatic craniotomies. Visual outcomes were similar to those in earlier reports, with 70% of patients reporting stable to normal vision postoperatively. CONCLUSION OPCMs can occur throughout the anterior visual pathway and may cause significant symptoms. Surgery is feasible and should be considered for OPCMs presenting to a surface of the nerve. Favorable results can be obtained with resection, although optimal results are obtained with patients who present with milder symptoms without longstanding damage to the optic apparatus.

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