Repair of Large Bone Defects with the Use of Autologous Bone Marrow Stromal Cells

2001 ◽  
Vol 344 (5) ◽  
pp. 385-386 ◽  
Author(s):  
Rodolfo Quarto ◽  
Maddalena Mastrogiacomo ◽  
Ranieri Cancedda ◽  
Sergei M. Kutepov ◽  
Vladimir Mukhachev ◽  
...  
2013 ◽  
Vol 2013 ◽  
pp. 1-8 ◽  
Author(s):  
Xuehui Zhang ◽  
Mingming Xu ◽  
Xinggang Liu ◽  
Feng Zhang ◽  
Yan Wei ◽  
...  

Nano-β-tricalcium phosphate/collagen (n-β-TCP/Col) is considered with good osteoconductivity. However, the therapeutic effectiveness of n-β-TCP/Col scaffolds in combination with autologous bone marrow stromal cells (BMSCs) remains to be elucidated for the repair of critical-sized bone defects. In this study, we found that n-β-TCP/Col scaffolds exhibited high biocompatibilityin vitro. The introduction of BMSCs expandedin vitroto the scaffolds dramatically enhanced their efficiency to restore critical-sized bone defects, especially during the initial stage after implantation. Collectively, these results suggest that autologous BMSCs in n-β-TCP/Col scaffolds have the potential to be applied in bone tissue engineering.


2014 ◽  
Vol 12 (1) ◽  
pp. 123 ◽  
Author(s):  
Yefei Wang ◽  
Xiaoping Bi ◽  
Huifang Zhou ◽  
Yuan Deng ◽  
Jing Sun ◽  
...  

2008 ◽  
Vol 2 (5) ◽  
pp. 253-262 ◽  
Author(s):  
P. Giannoni ◽  
M. Mastrogiacomo ◽  
M. Alini ◽  
S. G. Pearce ◽  
A. Corsi ◽  
...  

2000 ◽  
Vol 192-195 ◽  
pp. 1053-0 ◽  
Author(s):  
Maurilio Marcacci ◽  
Elizaveta Kon ◽  
Rodolfo Quarto ◽  
Sergei M. Kutepov ◽  
Vladimir Mukhachev ◽  
...  

2006 ◽  
Vol 0 (0) ◽  
pp. 061017080728006
Author(s):  
Guangdong Zhou ◽  
Wei Liu ◽  
Lei Cui ◽  
Xiaoyun Wang ◽  
Tianyi Liu ◽  
...  

2006 ◽  
Vol 168 (2) ◽  
pp. 542-550 ◽  
Author(s):  
Mahesh H. Mankani ◽  
Sergei A. Kuznetsov ◽  
Brian Shannon ◽  
Ravi K. Nalla ◽  
Robert O. Ritchie ◽  
...  

Cardiology ◽  
2006 ◽  
Vol 108 (4) ◽  
pp. 228-236 ◽  
Author(s):  
Dingguo Zhang ◽  
Fumin Zhang ◽  
Yuqing Zhang ◽  
Xiang Gao ◽  
Chuanfu Li ◽  
...  

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