The unbonded prestressed concrete slabs is usually used in big span high-rise buildings. Due to the existence of stairs, elevators, piping shafts and washroom etc,(hole drilling is usually encountered in the floor of unbonded prestressed concrete structures), which weakens the rigidity of concrete slab, and it has different influences on the slabs with openings in different locations. Based on the contrast experiments of the unbonded prestressed concrete slab with openings in different locations subjected to uniform load, this thesis investigates and analyzes mechanical behavior of the unbonded prestressed concrete slabs with openings in different locations (central,around edge and corner) subjected to uniform load. Using the yield-line theory to calculate the ultimate bearing capacity of pre-stressed slabs with openings, and comparing from experimental results to theoretical ones, this paper puts forward some conclusions of how different opening locations impact the ultimate bearing capacity of pre-stressed slabs with openings