High resolution three-dimensional photoacoustic imaging of human finger joints in vivo

2015 ◽  
Vol 107 (6) ◽  
pp. 063701 ◽  
Author(s):  
Lei Xi ◽  
Huabei Jiang
2012 ◽  
Vol 38 (10) ◽  
pp. 1833-1838 ◽  
Author(s):  
Kazutoshi Kumagai ◽  
Hideyuki Koike ◽  
Ryo Nagaoka ◽  
Shingo Sakai ◽  
Kazuto Kobayashi ◽  
...  

2013 ◽  
Vol 45 (10) ◽  
pp. 628-632 ◽  
Author(s):  
Gangjun Liu ◽  
Wangcun Jia ◽  
J. Stuart Nelson ◽  
Zhongping Chen

Author(s):  
Gerard T. Luk-Pat ◽  
Garry E. Gold ◽  
Eric W. Olcott ◽  
Bob S. Hu ◽  
Dwight G. Nishimura

2006 ◽  
Author(s):  
Alexander D. Klose ◽  
Rong Song ◽  
Alexander K. Scheel ◽  
Uwe Netz ◽  
Jürgen Beuthan ◽  
...  

2005 ◽  
Vol 119 (9) ◽  
pp. 693-698 ◽  
Author(s):  
Beom-Cho Jun ◽  
Sun-Wha Song ◽  
Ju-Eun Cho ◽  
Chan-Soon Park ◽  
Dong-Hee Lee ◽  
...  

The aim of this study was to investigate the usefulness of a three-dimensional (3D) reconstruction of computed tomography (CT) images in determining the anatomy and topographic relationship between various important structures. Using 40 ears from 20 patients with various otological diseases, a 3D reconstruction based on the image data from spiral high-resolution CT was performed by segmentation, volume-rendering and surface-rendering algorithms on a personal computer. The 3D display of the middle and inner ear structures was demonstrated in detail. Computer-assisted measurements, many of which could not be easily measured in vivo, of the reconstructed structures provided accurate anatomic details that improved the surgeon’s understanding of spatial relationships. A 3D reconstruction of temporal bone CT might be useful for education and increasing understanding of the anatomical structures of the temporal bone. However, it will be necessary to confirm the correlation between the 3D reconstructed images and histological sections through a validation study.


Pain Medicine ◽  
2019 ◽  
Vol 20 (9) ◽  
pp. 1687-1696 ◽  
Author(s):  
André P Boezaart ◽  
Alberto Prats-Galino ◽  
Olga C Nin ◽  
Anna Carrera ◽  
José Barberán ◽  
...  

Abstract Objective Our aim was to study the posterior lumbar epidural space with 3D reconstructions of magnetic resonance images (MRIs) and to compare and validate the findings with targeted anatomic microdissections. Design We performed 3D reconstructions of high-resolution MRIs from seven patients and normal-resolution MRIs commonly used in clinical practice from 196 other random patients. We then dissected and photographed the lumbar spine areas of four fresh cadavers. Results From the 3D reconstructions of the MRIs, we verified that the distribution of the posterior fat pad had an irregular shape that resembled a truncated pyramid. It spanned between the superior margin of the lamina of the caudad vertebra and beyond the inferior margin to almost halfway underneath the cephalad lamina of the cranial vertebra, and it was not longitudinally or circumferentially continuous. The 3D reconstructions of the high-definition MRI also consistently revealed a prelaminar fibrous body that was not seen in most of the usually used low-definition MRI reconstructions. Targeted microdissections confirmed the 3D reconstruction findings and also showed the prelaminar tissue body to be fibrous, crossing from side to side anterior to the cephalad half of each lamina, and spanning from the dural sac to the laminae. Conclusions Three-dimensional reconstructions and targeted microdissection revealed the unique appearance of posterior fat pads and a prelaminar fibrous body. The exact consistency, presence, prevalence with age, presence in other regions, and function of this body are unknown and require further research.


2003 ◽  
Vol 16 (8) ◽  
pp. 484-493 ◽  
Author(s):  
P. Faure ◽  
B.-T. Doan ◽  
J.-C. Beloeil

Hypertension ◽  
2016 ◽  
Vol 68 (suppl_1) ◽  
Author(s):  
Liliya M Yamaleyeva ◽  
Tiffaney Bledsoe ◽  
K. Bridget Brosnihan

Placental hypoxia/ischemia induces abnormal maternal and neonatal outcomes including preeclampsia and intrauterine growth restriction (IUGR). The ability to accurately determine placental oxygenation in a non-invasive way and in real-time is highly important during pregnancy as it may allow for the early diagnosis of IUGR and preeclampsia. Photoacoustic imaging (PA) is a novel preclinical and emerging clinical tool that combines optical contrast of photoacoustic laser technology with high spatial resolution of ultrasound. PA measures tissue oxygen saturation (sO2) that reflects differences in absorption spectra for oxygenated and deoxygenated hemoglobin. By using photoacoustic features of VEVO LAZR high resolution ultrasound system (VisualSonics) in a three-dimensional mode we investigated the sensitivity and accuracy of PA for placental oxygenation in C57Bl/6 mice at day 14 of gestation. Furthermore, since nitric oxide deficiency is associated with upregulation of circulatory hypoxia markers, C57Bl/6 mice were chronically treated with the nitric oxide inhibitor, L-NAME via osmotic minipumps (50 mg/kg/day; days 13 to 18 of gestation). The comparisons between scanned vs. not scanned uteroplacental units showed that PA had no effect on fetal (scanned: 0.028±0.001 vs. not scanned: 0.03±0.001 g/maternal body weight; p>0.05) or placental (scanned: 0.002±0.003 vs. not scanned: 0.002±0.002 g/maternal body weight; p>0.05) weights in C57Bl/6 mice. Changing inhaled O2 from 100- to 20% resulted on average in 12.5% reduction in total placental sO2. Systolic blood pressures were higher in L-NAME-treated vs. C57Bl/6 mice (215.8±0.8 vs. sham 99.3±4.4 mmHg; p<0.05). L-NAME infusion decreased sO2 in all areas of the placenta: labyrinth (73.6±0.97 vs. 58.6±3.4%, p<0.05), mesometrial triangle (63.0±2.0 vs. 48.9±1.0%, p<0.05), and total placenta (68.2±1.7 vs. 54.4±2.2%, p<0.05). Placental labyrinth had higher sO2 vs. mesometrial triangle area in both L-NAME infused (58.6±3.4 vs. 48.9±1.0%, p<0.05) and in C57Bl/6 (73.6±0.97 vs. 63.0±2.0%, p<0.05) mice reflecting elaborate branching morphology of the labyrinth. Our data suggest that PA imaging can detect regional differences in placental sO2 non-invasively and at different physiological states.


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