Bilateral intrapleural analgesia with 0.375% bupivacaine as a routine therapy after Nuss procedure for pecus excavatum in children

2007 ◽  
Vol 1 (2) ◽  
pp. 145-152
Author(s):  
URSZULA IZWARYN ◽  
ANNA KUROŚ-WIKŁOŚ
Author(s):  
Yimin Xie ◽  
Jinbo Ning

Abstract Background/Purpose The Nuss procedure is the most common surgical repair for pectus excavatum (PE). Surgical steel wires are used in some modifications of the Nuss procedure to attach one or both ends of a support bar to the ribs. During follow-up, wire breakage was found in some cases. Patients with wire breakage may undergo prolonged bar removal surgery and may be exposed to excessive radiation.In this study, we had a series of patients who received polydioxanone suture (PDS) fixations instead of steel wires. This retrospective study was conducted to explore the differences between these two fixation materials in the incidence of related complications and efficacies. Furthermore, we attempted to observe whether the two materials lead to similar surgical efficacy in the Nuss procedure, whether they have divergent effects on the bar removal surgery, and whether PDS can reduce the risks due to steel wire breakage as expected. Methods We retrospectively studied PDS and surgical steel wires as fixation materials for the Nuss procedure in children with congenital PE and reviewed the outcomes and complications. A total of 75 children who had undergone Nuss procedure repairs and bar removals from January 2013 to December 2019 were recruited to participate in this study. They were divided into three groups: the PDS group, the unbroken wire (UBW) group, and the broken wire (BW) group, according to the fixation materials and whether the wires had broken or not. Moreover, we selected the duration of operation (DO), intraoperative blood loss (BL), bar displacement (BD), postoperative pain score (PPS), and incision infection as the risk indicators and the postrepair Haller index (HI) as the effectiveness indicator. These indicators were statistically compared to determine whether there were differences among the three groups. Results One BD occurred in the PDS and BW groups while none took place in the UBW group. No incision infection was found in any of the groups. The PDS group had the shortest DO, while the DO in the UBW group was shorter than that in the BW group (p < 0.05). BL in the PDS group was less than that in the other two groups (p < 0.05). Additionally, no difference was observed in BL between the BW and UBW groups (p > 0.05). The PPS of the PDS group was less than that of the BW group (p < 0.05), whereas no differences were found between the other two groups. No statistical difference emerged in HI among the groups (p > 0.05). Conclusion PDS fixation results in a similar repair outcome and shows certain advantages in the DO, BL, and PPS; also, PDSs are safe and effective in the Nuss procedure. Level of evidence Level III.


Diabetologia ◽  
2021 ◽  
Vol 64 (4) ◽  
pp. 778-794 ◽  
Author(s):  
Matthieu Wargny ◽  
◽  
Louis Potier ◽  
Pierre Gourdy ◽  
Matthieu Pichelin ◽  
...  

Abstract Aims/hypothesis This is an update of the results from the previous report of the CORONADO (Coronavirus SARS-CoV-2 and Diabetes Outcomes) study, which aims to describe the outcomes and prognostic factors in patients with diabetes hospitalised for coronavirus disease-2019 (COVID-19). Methods The CORONADO initiative is a French nationwide multicentre study of patients with diabetes hospitalised for COVID-19 with a 28-day follow-up. The patients were screened after hospital admission from 10 March to 10 April 2020. We mainly focused on hospital discharge and death within 28 days. Results We included 2796 participants: 63.7% men, mean age 69.7 ± 13.2 years, median BMI (25th–75th percentile) 28.4 (25.0–32.4) kg/m2. Microvascular and macrovascular diabetic complications were found in 44.2% and 38.6% of participants, respectively. Within 28 days, 1404 (50.2%; 95% CI 48.3%, 52.1%) were discharged from hospital with a median duration of hospital stay of 9 (5–14) days, while 577 participants died (20.6%; 95% CI 19.2%, 22.2%). In multivariable models, younger age, routine metformin therapy and longer symptom duration on admission were positively associated with discharge. History of microvascular complications, anticoagulant routine therapy, dyspnoea on admission, and higher aspartate aminotransferase, white cell count and C-reactive protein levels were associated with a reduced chance of discharge. Factors associated with death within 28 days mirrored those associated with discharge, and also included routine treatment by insulin and statin as deleterious factors. Conclusions/interpretation In patients with diabetes hospitalised for COVID-19, we established prognostic factors for hospital discharge and death that could help clinicians in this pandemic period. Trial registration Clinicaltrials.gov identifier: NCT04324736 Graphical abstract


2015 ◽  
Vol 50 (12) ◽  
pp. 2032-2034 ◽  
Author(s):  
Wendy Yang ◽  
Yung-Ching Ming ◽  
Yi-Chuan Kau ◽  
Chia-Chih Liao ◽  
Shih-Chang Tsai ◽  
...  

2009 ◽  
Vol 88 (6) ◽  
pp. 1773-1779 ◽  
Author(s):  
Marlos de Souza Coelho ◽  
Ruy Fernando Kuenzer Caetano Silva ◽  
Nelson Bergonse Neto ◽  
Wilson de Souza Stori ◽  
Anna Flávia Ribeiro dos Santos ◽  
...  

2005 ◽  
Vol 75 (6) ◽  
pp. 421-424 ◽  
Author(s):  
Caroline C. P. Ong ◽  
Kelvin Choo ◽  
Philip Morreau ◽  
Alex Auldist

2011 ◽  
Vol 65 (6) ◽  
pp. 317-321 ◽  
Author(s):  
Savina Aneja ◽  
James S. Taylor ◽  
Oliver Soldes ◽  
John DiFiore

2017 ◽  
Vol 23 (4) ◽  
pp. 175-180 ◽  
Author(s):  
Li Luo ◽  
Bo Xu ◽  
Xinling Wang ◽  
Bo Tan ◽  
Jing Zhao

2010 ◽  
Vol 37 (3) ◽  
pp. 747-748
Author(s):  
José M. Mier ◽  
Laureano Molins ◽  
Juan J. Flibla

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