scholarly journals Production of Severe Iodine Deficiency in Sheep Using a Prepared Low-Iodine Diet

1980 ◽  
Vol 33 (1) ◽  
pp. 53 ◽  
Author(s):  
BJ Potter ◽  
GB Jones ◽  
RA Buckley ◽  
GB Belling ◽  
GH McIntosh ◽  
...  
Keyword(s):  
Urinary Excretion ◽  
Blood Plasma ◽  
Iodine Deficiency ◽  
Thyroid Stimulating Hormone ◽  
Deficient Diet ◽  
Low Levels ◽  
In Blood Plasma ◽  
Stimulating Hormone

Extensive tests on dietary materials suitable for ingestion by sheep have led to the preparation of an appropriate diet which, when fed to the sheep, caused severe iodine deficiency. The deficiency was manifested by daily urinary excretion values which fell to levels of less than 20 pg iodine and by thyroxine (T4) and triiodothyronine (T3) concentrations in blood plasma which were reduced from more than 90 and 1�80 nmol/l to the low levels of less than 2�58 and 0�31 nmol/l respectively. The values were attained 5 months after feeding the low-iodine diet. Goitre was present in most of the animals and the reductions in T4 and T3 values were accompanied by increased concentrations of plasma thyroid stimulating hormone (TSH) from less than 8�6 to more than 68 ng/ml. Samples of wool removed from selected areas of the sheep showed that the iodine-deficient diet also caused a reduction in the growth of wool.

Neonatal thyroid‐stimulating hormone concentrations in northern Sydney: further indications of mild iodine deficiency?

2002 ◽  
Vol 176 (7) ◽  
pp. 317-320 ◽  
Author(s):  
Aidan McElduff ◽  
Patrick McElduff ◽  
Jenny E Gunton ◽  
Graham Hams ◽  
Veronica Wiley ◽  
...  
Keyword(s):  
Iodine Deficiency ◽  
Thyroid Stimulating Hormone ◽  
Stimulating Hormone

scholarly journals Neonatal Thyroid-Stimulating Hormone Concentrations in Belgium: A Useful Indicator for Detecting Mild Iodine Deficiency?

PLoS ONE ◽  
2012 ◽  
Vol 7 (10) ◽  
pp. e47770 ◽  
Author(s):  
Stefanie Vandevijvere ◽  
Wim Coucke ◽  
Jean Vanderpas ◽  
Caroline Trumpff ◽  
Maarten Fauvart ◽  
...  
Keyword(s):  
Iodine Deficiency ◽  
Thyroid Stimulating Hormone ◽  
Stimulating Hormone

scholarly journals Endocrine predictors of testicular biopsy efficacy in patients with azoospermia

2017 ◽  
Vol 176 (3) ◽  
pp. 38-42
Author(s):  
V. A. Toropov ◽  
S. Yu. Borovets ◽  
S. Kh. Al’-Shukri ◽  
A. M. Gzgzyan ◽  
V. Ya. Belousov ◽  
...  
Keyword(s):  
Blood Plasma ◽  
Follicle Stimulating Hormone ◽  
Testicular Biopsy ◽  
Sex Steroid ◽  
Testicular Sperm Extraction ◽  
Testicular Sperm ◽  
Low Probability ◽  
Steroid Binding ◽  
In Blood Plasma ◽  
Stimulating Hormone

OBJECTIVE. The study identified predictors of endocrine detection of sperm in case of open testicular biopsy in patients with non-obstructive azoospermia. MATERIAL AND METHODS. The research was based on the results of examination and testicular biopsy of 76 patients with secretory azoospermia aged from 20 to 55 years old. The instrumental, laboratory, physical methods of research were carried out for all the patients before performing of the open biopsy for testicular sperm extraction. Hormone levels were determined in blood plasma such as luteinizing hormone, follicle stimulating hormone, prolactin, total and free testosterone, estradiol and sex steroid binding globulin. Patients were divided into two groups. The first group consisted of patients (n =43) whom sperms were found in testicular biopsies. The second group included patients (n = 33) whom sperms weren’t detected. RESULTS. Сonсentration of follicle stimulating hormone in blood plasma was the most significant hormone predictor. It was found that follicle stimulating hormone level between 12 and 16 IU/L indicated to the low probability of sperm presence in testicular biopsies and in case it was less than 17 IU/L the probability was extremely low. There was also established that elevated follicle stimulating hormone levels in patients older than 26 years pointed to the low probability of finding sperm using open testicular sperm extraction. CONCLUSIONS. Increase of luteinizing hormone, follicle stimulating hormone or their correlation in blood plasma indicates to a low probability of finding sperm by open testicular sperm extraction. The concentrations of testosterone, sex steroid binding globulin, prolactin and estradiol in the blood plasma weren’t reliable predictors of finding sperm in testicular biopsies.

scholarly journals Neonatal Thyroid-Stimulating Hormone Screening as an Indirect Method for the Assessment of Iodine Status in Central Siberia

2018 ◽  
Vol 3 (4) ◽  
Keyword(s):  
Newborn Screening ◽  
Congenital Hypothyroidism ◽  
Iodine Deficiency ◽  
Screening Program ◽  
Thyroid Stimulating Hormone ◽  
The Arctic ◽  
Central Siberia ◽  
Iodine Status ◽  
The Republic ◽  
Stimulating Hormone

Background: Iodine deficiency is associated with goiter and impaired brain function. Neonatal thyroid-stimulating hormone (TSH) screening for congenital hypothyroidism used as an indicator of the degree of iodine deficiency and of its control. An increased frequency of thyroid-stimulating hormone (TSH) measurements above 5 mIU/L in newborn screening corresponds to the impaired iodine status of the population. The aim: to estimate the iodine deficiency and the effectiveness of iodine prophylaxis in Krasnoyarsk territory, Republics of Tuva and Khakassia according the results of neonatal TSH_screening. Methods: An 18-year analysis was performed in 34,980 newborns participating in the national thyroid newborn screening program. The TSH concentration was measured in dry blood spots collected by heel stick on filter paper, 96 hours after birth, using DELFIA method. Results: According to the data of the congenital hypothyroidism screening the rate of TSH < 5 mU/1 was 11.8% in Krasnoyarsk territory (23.9% in 2000) and corresponded to mild iodine deficiency. In different regions of Krasnoyarsk territory the rate of TSH < 5 mU/1 in the newborn varied from 3.5% to 23.7%. The highest values were marked in the Arctic peninsula Taimyr, in cities Zheleznogorsk (nuclear facility) and Sosnovoborsk, in Irbeysky, Suchobuzimsky, Eniseysky, Tuchtetsky, Novoselovsky regions (20.9–23.7%). In the Republic of Khakasia the rate of TSH < 5 mU/1 was 12.5%. In the Republic of Tyva the rate of TSH < 5 mU/1 was – 6.6% (38.6% in 1997; 11.5% in 2000). These results indicate mild iodine deficiency. Conclusion: Our investigations show mild iodine deficiency in Central Siberia demanding continuous adequate iodine prevention. Additional assessment of the iodine intake in the regions with mild iodine deficiency is needed to prevent suboptimal cognitive and psychomotor outcomes.

Increased iodine deficiency in Victoria, Australia: analysis of neonatal thyroid‐stimulating hormone data, 2001 to 2006

2011 ◽  
Vol 194 (4) ◽  
pp. 209-210
Author(s):  
Ashequr Rahman ◽  
Gayle S Savige ◽  
Nicholas J Deacon ◽  
Ivan Francis ◽  
Janice E Chesters
Keyword(s):  
Iodine Deficiency ◽  
Thyroid Stimulating Hormone ◽  
Stimulating Hormone

A SOLID-PHASE RADIOIMMUNOASSAY FOR OVINE FOLLICLE-STIMULATING HORMONE

1973 ◽  
Vol 58 (2) ◽  
pp. 239-249 ◽  
Author(s):  
N. F. CUNNINGHAM ◽  
C. NANCY HEBERT
Keyword(s):  
Luteinizing Hormone ◽  
Blood Plasma ◽  
Solid Phase ◽  
Follicle Stimulating Hormone ◽  
Thyroid Stimulating Hormone ◽  
Cross Reaction ◽  
Sheep Blood ◽  
Solid Phase Radioimmunoassay ◽  
Stimulating Hormone

SUMMARY A radioimmunoassay using antibody-coated polystyrene tubes is described, which is suitable for the estimation of follicle-stimulating hormone (FSH) levels in sheep blood plasma. Ovine FSH was labelled with 125I by an enzymic method employing lactoperoxidase and H2O2, and was stable for several months at −15 °C. Antisera to ovine FSH were raised in rabbits. Standard curves for unlabelled FSH obtained by this method with different preparations of labelled FSH showed reproducible slopes from day to day. Ovine luteinizing hormone (LH) and thyroid-stimulating hormone (TSH) showed about 17% cross-reaction in the assay, necessitating the application of a correction to the FSH values for samples of plasma containing more than 15 ng of LH or TSH/ml. The FSH content of plasma from wethers and anoestrous ewes ranged from 20 to 120 ng/ml.

Cord blood thyroid-stimulating hormone and free T4 levels in Turkish neonates: Is iodine deficiency still a continuing problem?

2010 ◽  
Vol 52 (5) ◽  
pp. 762-768 ◽  
Author(s):  
Fatih Kışlal ◽  
Semra Çetinkaya ◽  
Uğur Dilmen ◽  
Handan Yaşar ◽  
Tahsin Teziç
Keyword(s):  
Cord Blood ◽  
Iodine Deficiency ◽  
Thyroid Stimulating Hormone ◽  
Free T4 ◽  
Stimulating Hormone

Increased iodine deficiency in Victoria, Australia: analysis of neonatal thyroid‐stimulating hormone data, 2001 to 2006

2010 ◽  
Vol 193 (9) ◽  
pp. 503-505 ◽  
Author(s):  
Ashequr Rahman ◽  
Gayle S Savige ◽  
Nicholas J Deacon ◽  
Ivan Francis ◽  
Janice E Chesters
Keyword(s):  
Iodine Deficiency ◽  
Thyroid Stimulating Hormone ◽  
Stimulating Hormone
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