Synthesis and Spectroscopic Characterization of β-Di-, β-Tri-, and β-Hexapeptides Built with (S)-2-Methylene-3-aminoalkanoic Acids Derived from Alanine, Valine, and Leucine
Keyword(s):
Methylthiomethylation and subsequent sulfoxidation and pyrolysis of the N-Boc-protected β3-amino acid methyl esters derived from Ala, Val, and Leu provided the α-methylene esters; these were then used to synthesize the β-peptides specified in the title (step-by-step and fragment coupling in solution). The novel β-peptides were fully characterized, but neither solid-state nor solution structures were found.
1983 ◽
Vol 258
(15)
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pp. 9270-9275
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1981 ◽
Vol 256
(12)
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pp. 6047-6053
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1988 ◽
Vol 27
(2)
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pp. 274-275
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2010 ◽
Vol 636
(1)
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pp. 236-241
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2014 ◽
Vol 26
(7-8)
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pp. 521-525
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