Reactions of Perimidin-4-ones and -6-ones with amines
Keyword(s):
π-Deficient perimidin-4- and -6-one systems reacted readily with primary and secondary amines at room temperature. Nucleophilic attack occurred not only at the enone double bond, but also at positions 7 and 9 on the benzenoid ring. Highly coloured mono-, di- or tri-aminated derivatives were thereby obtained. A significant degree of bond fixation was indicated. Side-chain amination of 9-methyl substituents was observed, analogous to processes encountered in quinone chemistry. On continued contact with amine the products were converted partly into 9-formyl derivatives and partly into 9-amino compounds.
2021 ◽
1960 ◽
Vol 25
(7)
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pp. 1175-1179
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Keyword(s):
1994 ◽
Vol 59
(5)
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pp. 1095-1101
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Keyword(s):
2010 ◽
Vol 51
(17)
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pp. 2319-2322
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