Reaction of 4,6-Dimethoxy-3-methylindole With Aromatic Aldehydes: a Simple Synthesis of Calix[3]indoles

1996 ◽  
Vol 49 (3) ◽  
pp. 311 ◽  
Author(s):  
DS Black ◽  
DC Craig ◽  
N Kumar

2,7:2,7:2,7-Linked calix [3] indoles (3a-d) have been prepared by the reaction of 4,6-dimethoxy-3-methylindole (1) and benzaldehydes with phosphoryl chloride or by a direct reaction of di (4,6-dimethoxy-3-methylindol-2-yl) phenylmethanes (2a-d) with phosphoryl chloride. An X-ray crystal structure determination of the macrocycle (3d) is reported. 4,6-Dimethoxy-3-methylindolemethanols (9) and (10) were prepared and reacted with phosphoryl chloride to study the mechanism of formation of the macrocycle.

2012 ◽  
Vol 524 ◽  
pp. 22-25 ◽  
Author(s):  
Hiroshi Nozaki ◽  
Tatsuo Fukano ◽  
Shingo Ohta ◽  
Yoshiki Seno ◽  
Hironori Katagiri ◽  
...  

2008 ◽  
Vol 48 (supplement) ◽  
pp. S142
Author(s):  
Michihiro Suga ◽  
Kyoko Ito-Shinzawa ◽  
Hiroshi Aoyama ◽  
Kazumasa Muramoto ◽  
Eiki Yamashita ◽  
...  

ChemInform ◽  
2010 ◽  
Vol 28 (5) ◽  
pp. no-no
Author(s):  
D. R. KELLY ◽  
A. A. EDWARDS ◽  
J. A. PARKINSON ◽  
G. OLOVSSON ◽  
J. TROTTER ◽  
...  

2007 ◽  
Vol 222 (10) ◽  
Author(s):  
Martin U. Schmidt ◽  
Jürgen Brüning ◽  
Christian Buchsbaum ◽  
Edith Alig ◽  
Lothar Fink

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