Reaction of 4,6-Dimethoxy-3-methylindole With Aromatic Aldehydes: a Simple Synthesis of Calix[3]indoles
Keyword(s):
2,7:2,7:2,7-Linked calix [3] indoles (3a-d) have been prepared by the reaction of 4,6-dimethoxy-3-methylindole (1) and benzaldehydes with phosphoryl chloride or by a direct reaction of di (4,6-dimethoxy-3-methylindol-2-yl) phenylmethanes (2a-d) with phosphoryl chloride. An X-ray crystal structure determination of the macrocycle (3d) is reported. 4,6-Dimethoxy-3-methylindolemethanols (9) and (10) were prepared and reacted with phosphoryl chloride to study the mechanism of formation of the macrocycle.
2012 ◽
Vol 524
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pp. 22-25
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Keyword(s):
1993 ◽
pp. 1625
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1982 ◽
Vol 51
(11)
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pp. 3583-3591
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2000 ◽
Vol 2000
(1)
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pp. 21-28
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