Structure-based discovery of 2-adrenergic receptor ligands

Proceedings of the National Academy of Sciences ◽

10.1073/pnas.0812657106 ◽

2009 ◽

Vol 106 (16) ◽

pp. 6843-6848 ◽

Author(s):

P. Kolb ◽

D. M. Rosenbaum ◽

J. J. Irwin ◽

J. J. Fung ◽

B. K. Kobilka ◽

...

Keyword(s):

Adrenergic Receptor ◽

Receptor Ligands ◽

Adrenergic Receptor Ligands

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Receptor Regulatory Properties Evident in the Molecular Similarity of β-Adrenergic Receptor Ligands and Adenosine Triphosphate

Pharmacy and Pharmacology Communications ◽

10.1211/146080899128735324 ◽

1999 ◽

Vol 5 (9) ◽

pp. 545-553 ◽

Author(s):

W.R. Williams ◽

W.J. Pugh ◽

P.J. Nicholls

Keyword(s):

Adenosine Triphosphate ◽

Adrenergic Receptor ◽

Molecular Similarity ◽

Receptor Ligands ◽

Adrenergic Receptor Ligands ◽

Regulatory Properties

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Diverse arrestin-recruiting and endocytic profiles of tricyclic antipsychotics acting as direct α 2A adrenergic receptor ligands

Neuropharmacology ◽

10.1016/j.neuropharm.2016.12.004 ◽

2017 ◽

Vol 116 ◽

pp. 38-49 ◽

Author(s):

Christopher Cottingham ◽

Pulin Che ◽

Wei Zhang ◽

Hongxia Wang ◽

Raymond X. Wang ◽

...

Keyword(s):

Adrenergic Receptor ◽

Receptor Ligands ◽

Adrenergic Receptor Ligands

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Role of α-Adrenergic Receptors in the Effect of the β-Adrenergic Receptor Ligands, CGP 12177, Bupranolol, and SR 59230A, on the Contraction of Rat Intrapulmonary Artery

Journal of Pharmacology and Experimental Therapeutics ◽

10.1124/jpet.103.061192 ◽

2004 ◽

Vol 309 (1) ◽

pp. 137-145 ◽

Author(s):

Véronique Leblais ◽

Fabrice Pourageaud ◽

M. Dolores Ivorra ◽

Christelle Guibert ◽

Roger Marthan ◽

...

Keyword(s):

Adrenergic Receptors ◽

Adrenergic Receptor ◽

Receptor Ligands ◽

Cgp 12177 ◽

Adrenergic Receptor Ligands

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Distinct Signaling Profiles of β1 and β2 Adrenergic Receptor Ligands toward Adenylyl Cyclase and Mitogen-Activated Protein Kinase Reveals the Pluridimensionality of Efficacy

Molecular Pharmacology ◽

10.1124/mol.106.026716 ◽

2006 ◽

Vol 70 (5) ◽

pp. 1575-1584 ◽

Author(s):

Ségolène Galandrin ◽

Michel Bouvier

Keyword(s):

Protein Kinase ◽

Adenylyl Cyclase ◽

Adrenergic Receptor ◽

Mitogen Activated Protein Kinase ◽

Receptor Ligands ◽

Mitogen Activated Protein ◽

Β2 Adrenergic Receptor ◽

Adrenergic Receptor Ligands

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An Efficient Cyclic AMP Assay for the Functional Evaluation of β-Adrenergic Receptor Ligands

Journal of Receptors and Signal Transduction ◽

10.3109/10799899909042877 ◽

1999 ◽

Vol 19 (5) ◽

pp. 853-863 ◽

Author(s):

Sandeep S. Vansal ◽

Dennis R. Feller

Keyword(s):

Adrenergic Receptor ◽

Functional Evaluation ◽

Receptor Ligands ◽

Adrenergic Receptor Ligands

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1-Arylpiperazinyl-4-cyclohexylamine derived isoindole-1,3-diones as potent and selective α-1a/1d adrenergic receptor ligands

Bioorganic & Medicinal Chemistry Letters ◽

10.1016/j.bmcl.2006.12.111 ◽

2007 ◽

Vol 17 (6) ◽

pp. 1646-1650 ◽

Author(s):

Shengjian Li ◽

George Chiu ◽

Virginia L. Pulito ◽

Jingchun Liu ◽

Peter J. Connolly ◽

...

Keyword(s):

Adrenergic Receptor ◽

Receptor Ligands ◽

Adrenergic Receptor Ligands

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ChemInform Abstract: Synthesis of 2(3H)-Benzoxazolone and 2(3H)-Benzothiazolone Derivatives as Potential Beta-3-adrenergic Receptor Ligands. Part 2.

10.1002/chin.200141154 ◽

2010 ◽

Vol 32 (41) ◽

pp. no-no

Author(s):

J. F. Delhomel ◽

S. Yous ◽

P. Depreux ◽

D. Lesieur

Keyword(s):

Adrenergic Receptor ◽

Receptor Ligands ◽

Adrenergic Receptor Ligands

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ChemInform Abstract: Synthesis of 2(3H)-Benzoxazolinone Derivatives as Potential Beta-3-adrenergic Receptor Ligands.

10.1002/chin.200014111 ◽

2010 ◽

Vol 31 (14) ◽

pp. no-no

Author(s):

J. F. Delhomel ◽

S. Yous ◽

P. Depreux ◽

D. Lesieur

Keyword(s):

Adrenergic Receptor ◽

Receptor Ligands ◽

Adrenergic Receptor Ligands

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Search for β2 Adrenergic Receptor Ligands by Virtual Screening via Grid Computing and Investigation of Binding Modes by Docking and Molecular Dynamics Simulations

PLoS ONE ◽

10.1371/journal.pone.0107837 ◽

2014 ◽

Vol 9 (9) ◽

pp. e107837 ◽

Author(s):

Qifeng Bai ◽

Yonghua Shao ◽

Dabo Pan ◽

Yang Zhang ◽

Huanxiang Liu ◽

...

Keyword(s):

Molecular Dynamics ◽

Virtual Screening ◽

Grid Computing ◽

Molecular Dynamics Simulations ◽

Adrenergic Receptor ◽

Binding Modes ◽

Receptor Ligands ◽

Β2 Adrenergic Receptor ◽

Dynamics Simulations ◽

Adrenergic Receptor Ligands

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Theoretical quantitative size and shape activity and selectivity analyses of 5-HT1A serotonin and α1-adrenergic receptor ligands

Journal of Molecular Structure THEOCHEM ◽

10.1016/0166-1280(94)80145-2 ◽

1994 ◽

Vol 305 ◽

pp. 101-110 ◽

Author(s):

P.G. De Benedetti ◽

M. Cocchi ◽

M.C. Menziani ◽

F. Fanelli

Keyword(s):

Adrenergic Receptor ◽

Receptor Ligands ◽

Size And Shape ◽

Adrenergic Receptor Ligands

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