scholarly journals A small RNA induced late in simian virus 40 infection can associate with early viral mRNAs.

1980 ◽  
Vol 77 (3) ◽  
pp. 1379-1383 ◽  
Author(s):  
J. C. Alwine ◽  
R. Dhar ◽  
G. Khoury
Keyword(s):  
Small Rna ◽  
Simian Virus 40 ◽  
Simian Virus ◽  
Viral Mrnas

scholarly journals Inability of Simian Virus 40 To Establish Productive Infection of Lymphoblastic Cell Lines

2004 ◽  
Vol 78 (9) ◽  
pp. 4917-4920 ◽  
Author(s):  
Sophie Shaikh ◽  
Christine Skoczylas ◽  
Richard Longnecker ◽  
Kathleen Rundell
Keyword(s):  
Gene Expression ◽  
Cell Lines ◽  
Human Lymphocytes ◽  
Plaque Assay ◽  
Simian Virus 40 ◽  
Simian Virus ◽  
Early Gene ◽  
Productive Infection ◽  
Cell Type ◽  
Viral Mrnas

ABSTRACT Lymphoblastic cell lines were infected with simian virus 40 (SV40) and then monitored for evidence of a productive infection. No evidence of early gene expression was found 2 days following infection, as determined by assaying viral mRNAs and early antigens. Furthermore, only small amounts of virus could be detected by plaque assay 2 days after infection, and levels slowly declined until they were undetectable after a few weeks in culture. Thus, human lymphocytes are not readily infectible with SV40 and do not provide a simple model for studying interactions of SV40 with a human cell type.

Expression of enhanced levels of small RNA polymerase III transcripts encoded by the B2 repeats in simian virus 40-transformed mouse cells

Nature ◽  
1985 ◽  
Vol 314 (6011) ◽  
pp. 553-556 ◽  
Author(s):  
Karambir Singh ◽  
Michael Carey ◽  
Sentob Saragosti ◽  
Michael Botchan
Keyword(s):  
Rna Polymerase ◽  
Small Rna ◽  
Rna Polymerase Iii ◽  
Simian Virus 40 ◽  
Simian Virus ◽  
Polymerase Iii ◽  
Mouse Cells
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