scholarly journals Interaction of [3H]MK-801 with multiple states of the N-methyl-D-aspartate receptor complex of rat brain.

1989 ◽  
Vol 86 (2) ◽  
pp. 740-744 ◽  
Author(s):  
D. C. Javitt ◽  
S. R. Zukin
Life Sciences ◽  
1990 ◽  
Vol 46 (15) ◽  
pp. 1103-1110 ◽  
Author(s):  
Richard W. Ransom ◽  
Wai-si Eng ◽  
H.Donald Burns ◽  
Raymond E. Gibson ◽  
Howard F. Solomon

1989 ◽  
Vol 9 (5) ◽  
pp. 709-712 ◽  
Author(s):  
D. Dewar ◽  
M. C. Wallace ◽  
A. Kurumaji ◽  
J. McCulloch

The functional integrity of the N-methyl-d-aspartate receptor complex following focal cerebral ischemia in the rat has been examined at a time when brain tissue is irreversibly damaged. Twelve hours after unilateral permanent middle cerebral artery occlusion, [3H]-MK-801 binding was not significantly altered in the ischemic cerebral cortex compared to sham-operated animals. Moreover, the enhancement of [3H]MK-801 binding by exogenous glutamate was preserved in an area of the brain that was permanently damaged by the ischemic insult.


1991 ◽  
Vol 56 (4) ◽  
pp. 1248-1254 ◽  
Author(s):  
J. E. Steele ◽  
T. N. Robinson ◽  
A. J. Cross ◽  
D. M. Bowen ◽  
A. R. Green

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