scholarly journals Molecular cloning of a rat chromosome putative recombinogenic sequence homologous to the hepatitis B virus encapsidation signal.

1996 ◽  
Vol 93 (14) ◽  
pp. 7300-7304 ◽  
Author(s):  
H. Aoki ◽  
K. Kajino ◽  
Y. Arakawa ◽  
O. Hino
Keyword(s):  
Hepatitis B Virus ◽  
Hepatitis B ◽  
Molecular Cloning ◽  
Encapsidation Signal ◽  
B Virus

scholarly journals Formation of a Functional Hepatitis B Virus Replication Initiation Complex Involves a Major Structural Alteration in the RNA Template

1998 ◽  
Vol 18 (11) ◽  
pp. 6265-6272 ◽  
Author(s):  
Jürgen Beck ◽  
Michael Nassal
Keyword(s):  
Hepatitis B Virus ◽  
Hepatitis B ◽  
Replication Initiation ◽  
State Structure ◽  
Duck Hepatitis ◽  
P Protein ◽  
Encapsidation Signal ◽  
B Virus ◽  
Covalently Linked

ABSTRACT The DNA genome of a hepatitis B virus is generated by reverse transcription of the RNA pregenome. Replication initiation does not involve a nucleic acid primer; instead, the hepadnavirus P protein binds to the structured RNA encapsidation signal ɛ, from which it copies a short DNA primer that becomes covalently linked to the enzyme. Using in vitro-translated duck hepatitis B virus (DHBV) P protein, we probed the secondary structure of the protein-bound DHBV ɛ RNA (Dɛ) and observed a marked conformational change compared to free Dɛ RNA. Several initiation-competent mutant RNAs with a different free-state structure were similarly altered, whereas a binding-competent but initiation-deficient variant was not, indicating the importance of the rearrangement for replication initiation and suggesting a mechanistic coupling to encapsidation.

Structure Elucidation of the Hepatitis B Virus Encapsidation Signal by NMR on Selectively Labeled RNAs

2002 ◽  
Vol 19 (4) ◽  
pp. 627-636 ◽  
Author(s):  
Sara Flodell ◽  
Jenny Cromsigt ◽  
Jürgen Schleucher ◽  
Karin Kidd-Ljunggren ◽  
Sybren Wijmenga
Keyword(s):  
Hepatitis B Virus ◽  
Hepatitis B ◽  
Structure Elucidation ◽  
Encapsidation Signal ◽  
B Virus

scholarly journals Solution structure of the apical stem–loop of the human hepatitis B virus encapsidation signal

2006 ◽  
Vol 34 (16) ◽  
pp. 4449-4457 ◽  
Author(s):  
Sara Flodell ◽  
Michael Petersen ◽  
Frederic Girard ◽  
Janusz Zdunek ◽  
Karin Kidd-Ljunggren ◽  
...  
Keyword(s):  
Hepatitis B Virus ◽  
Hepatitis B ◽  
Solution Structure ◽  
Stem Loop ◽  
Human Hepatitis ◽  
Encapsidation Signal ◽  
B Virus

Host cell proteins binding to the encapsidation signal in hepatitis B virus RNA

2002 ◽  
Vol 147 (3) ◽  
pp. 471-491 ◽  
Author(s):  
H. J. Shin ◽  
S. S. Kim ◽  
Y. H. Cho ◽  
S. G. Lee ◽  
H. M. Rho
Keyword(s):  
Hepatitis B Virus ◽  
Hepatitis B ◽  
Host Cell ◽  
Host Cell Proteins ◽  
Virus Rna ◽  
Encapsidation Signal ◽  
B Virus
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