Vascular endothelial growth factor: Crystal structure and functional mapping of the kinase domain receptor binding site

Growth Factor ◽

Binding Site ◽

Receptor Binding ◽

Kinase Domain ◽

Functional Mapping ◽

Vascular Endothelial ◽

Receptor Binding Site ◽

Novel Peptides Selected to Bind Vascular Endothelial Growth Factor Target the Receptor-Binding Site

Biochemistry ◽

10.1021/bi981931e ◽

1998 ◽

Vol 37 (51) ◽

pp. 17754-17764 ◽

Cited By ~ 140

Author(s):

Wayne J. Fairbrother ◽

Hans W. Christinger ◽

Andrea G. Cochran ◽

Germaine Fuh ◽

Christopher J. Keenan ◽

...

Keyword(s):

Growth Factor ◽

Binding Site ◽

Receptor Binding ◽

Vascular Endothelial ◽

Receptor Binding Site ◽

Crystal structure of the kinase domain of human vascular endothelial growth factor receptor 2: a key enzyme in angiogenesis

Structure ◽

10.1016/s0969-2126(99)80042-2 ◽

1999 ◽

Vol 7 (3) ◽

pp. 319-330 ◽

Cited By ~ 123

Author(s):

Michele A McTigue ◽

John A Wickersham ◽

Chris Pinko ◽

Richard E Showalter ◽

Camran V Parast ◽

...

Keyword(s):

Crystal Structure ◽

Growth Factor ◽

Growth Factor Receptor ◽

Kinase Domain ◽

Vascular Endothelial ◽

Key Enzyme ◽

Crystal Structure of Human Vascular Endothelial Growth Factor-B: Identification of Amino Acids Important for Receptor Binding

Journal of Molecular Biology ◽

10.1016/j.jmb.2006.03.002 ◽

2006 ◽

Vol 359 (1) ◽

pp. 76-85 ◽

Cited By ~ 26

Author(s):

Shalini Iyer ◽

Pierre D. Scotney ◽

Andrew D. Nash ◽

K. Ravi Acharya

Keyword(s):

Crystal Structure ◽

Amino Acids ◽

Growth Factor ◽

Receptor Binding ◽

Vascular Endothelial ◽

Factor B ◽

The crystal structure of vascular endothelial growth factor (VEGF) refined to 1.93 Å resolution: multiple copy flexibility and receptor binding

Structure ◽

10.1016/s0969-2126(97)00284-0 ◽

1997 ◽

Vol 5 (10) ◽

pp. 1325-1338 ◽

Cited By ~ 151

Author(s):

Yves A Muller ◽

Hans W Christinger ◽

Bruce A Keyt ◽

Abraham M de Vos

Keyword(s):

Crystal Structure ◽

Growth Factor ◽

Receptor Binding ◽

Vascular Endothelial ◽

Multiple Copy ◽

Human Chorionic Gonadotropin (hCG) Alters Testosterone Secretion to Down-Regulate Relative Expression of Vascular Endothelial Growth Factor Isoform 188 VEGFA188 and Kinase Domain Region Receptor (KDR) in the Testes of Adult Mice.

Biology of Reproduction ◽

10.1093/biolreprod/81.s1.674 ◽

2009 ◽

Vol 81 (Suppl_1) ◽

pp. 674-674

Author(s):

Debra Clopton ◽

Rebecca Bott ◽

Ningxia Lu ◽

Racheal Slattery ◽

Andrea S. Cupp

Keyword(s):

Growth Factor ◽

Chorionic Gonadotropin ◽

Human Chorionic Gonadotropin ◽

Kinase Domain ◽

Vascular Endothelial ◽

Relative Expression ◽

Testosterone Secretion ◽

Adult Mice ◽

1H, 13C, and 15N backbone assignment and secondary structure of the receptor-binding domain of vascular endothelial growth factor

Protein Science ◽

10.1002/pro.5560061020 ◽

2008 ◽

Vol 6 (10) ◽

pp. 2250-2260 ◽

Cited By ~ 13

Author(s):

Wayne J. Fairbrother ◽

Mark A. Champe ◽

Hans W. Christinger ◽

Bruce A. Keyt ◽

Melissa A. Starovasnik

Keyword(s):

Growth Factor ◽

Secondary Structure ◽

Receptor Binding ◽

Backbone Assignment ◽

Binding Domain ◽

Vascular Endothelial ◽

Receptor Binding Domain ◽

Cytomegalovirus Upregulates Vascular Endothelial Growth Factor and Its Second Cellular Kinase Domain Receptor in Human Fibroblasts

Viral Immunology ◽

10.1089/vim.2012.0028 ◽

2012 ◽

Vol 25 (5) ◽

pp. 360-367 ◽

Cited By ~ 3

Author(s):

Andreas Heiske ◽

Yvonne Roettger ◽

Michael Bacher

Keyword(s):

Growth Factor ◽

Human Fibroblasts ◽

Kinase Domain ◽

Vascular Endothelial ◽

Vascular Endothelial Growth Factor and Kinase Domain Region Receptor Are Involved in Both Seminiferous Cord Formation and Vascular Development During Testis Morphogenesis in the Rat1

Biology of Reproduction ◽

10.1095/biolreprod.105.047225 ◽

2006 ◽

Vol 75 (1) ◽

pp. 56-67 ◽

Cited By ~ 56

Author(s):

Rebecca C. Bott ◽

Ryann M. McFee ◽

Debra T. Clopton ◽

Candice Toombs ◽

Andrea S. Cupp

Keyword(s):

Growth Factor ◽

Vascular Development ◽

Kinase Domain ◽

Vascular Endothelial ◽

Insights into the Conformational Switching Mechanism of the Human Vascular Endothelial Growth Factor Receptor Type 2 Kinase Domain

Journal of Chemical Information and Modeling ◽

10.1021/ci200513a ◽

2012 ◽

Vol 52 (2) ◽

pp. 483-491 ◽

Cited By ~ 5

Author(s):

Matteo Chioccioli ◽

Simone Marsili ◽

Claudia Bonaccini ◽

Piero Procacci ◽

Paola Gratteri

Keyword(s):

Growth Factor ◽

Growth Factor Receptor ◽

Kinase Domain ◽

Receptor Type ◽

Vascular Endothelial ◽

Conformational Switching ◽

Switching Mechanism ◽

The VD1 Neutralizing Antibody to Vascular Endothelial Growth Factor-D: Binding Epitope and Relationship to Receptor Binding

Journal of Molecular Biology ◽

10.1016/j.jmb.2011.02.009 ◽

2011 ◽

Vol 407 (4) ◽

pp. 581-593 ◽

Cited By ~ 10

Author(s):

Natalia Davydova ◽

Sally Roufail ◽

Victor A. Streltsov ◽

Steven A. Stacker ◽

Marc G. Achen

Keyword(s):

Growth Factor ◽

Receptor Binding ◽

Neutralizing Antibody ◽

Vascular Endothelial ◽

Binding Epitope ◽