scholarly journals Tsetse thrombin inhibitor: Bloodmeal-induced expression of an anticoagulant in salivary glands and gut tissue of Glossina morsitans morsitans

1998 ◽  
Vol 95 (24) ◽  
pp. 14290-14295 ◽  
Author(s):  
M. Cappello ◽  
S. Li ◽  
X. Chen ◽  
C.-B. Li ◽  
L. Harrison ◽  
...  
Keyword(s):  
Salivary Glands ◽  
Glossina Morsitans Morsitans ◽  
Thrombin Inhibitor ◽  
Glossina Morsitans ◽  
Induced Expression

Trypanosome infections and survival in tsetse

Parasitology ◽  
1998 ◽  
Vol 116 (S1) ◽  
pp. S23-S28 ◽  
Author(s):  
I. Maudlin ◽  
S. C. Welburn ◽  
P. J. M. Milligan
Keyword(s):  
Salivary Gland ◽  
Salivary Glands ◽  
Trypanosoma Brucei ◽  
Glossina Morsitans Morsitans ◽  
Trypanosoma Congolense ◽  
Vectorial Capacity ◽  
Trypanosome Infection ◽  
Trypanosoma Brucei Rhodesiense ◽  
Glossina Morsitans ◽  
Differential Effects

SummaryThe effect of trypanosome infection on vector survival was observed in a line of Glossina morsitans morsitans selected for susceptibility to trypanosome infection. The differential effects of midgut and salivary gland infections on survival were examined by exposing flies to infection with either Trypanosoma congolense which colonizes midgut and mouthparts or Trypanosoma brucei rhodesiense which colonizes midgut and salivary glands. A comparison of the survival distributions of uninfected flies with those exposed to infection showed that salivary gland infection significantly reduces tsetse survival; midgut infection had little or no effect on the survival of tsetse. The significance of these findings is discussed in relation to the vectorial capacity of wild flies.

An immunoregulatory peptide from tsetse fly salivary glands of Glossina morsitans morsitans

Biochimie ◽  
2015 ◽  
Vol 118 ◽  
pp. 123-128 ◽  
Author(s):  
Xuewei Bai ◽  
Huimin Yao ◽  
Canwei Du ◽  
Yan Chen ◽  
Ren Lai ◽  
...  
Keyword(s):  
Salivary Glands ◽  
Glossina Morsitans Morsitans ◽  
Tsetse Fly ◽  
Glossina Morsitans

Feeding behaviour ofGlossina morsitans morsitansinfected withTrypanosoma vivax, T. congolenseorT. brucei

Parasitology ◽  
1983 ◽  
Vol 86 (1) ◽  
pp. 51-56 ◽  
Author(s):  
S. K. Moloo
Keyword(s):  
Salivary Glands ◽  
Blood Meal ◽  
Feeding Behaviour ◽  
Glossina Morsitans Morsitans ◽  
Trypanosoma Vivax ◽  
Glossina Morsitans ◽  
Total Blood ◽  
Mean Frequency ◽  
Meal Intake ◽  
Multiple Probe

SUMMARYThe feeding behaviour ofGlossina morsitans morsitansinfected withTrypanosoma vivax, T. congolenseorT. bruceiwas studied and compared with that of uninfected control tsetse. The following parameters were measured. (1) Mean number of feeds taken in 20 consecutive days; (2) mean rate of blood meal intake in μg/sec of the total days fed; (3) mean weight of blood meal intake/day of the total days fed; (4) mean total blood meal engorgement in 20 days; (5) mean number of probes/day of the days fed; (6) mean frequency of the multiple probe feeds and (7) mean number of pre-feeding probes of the multiple probe feeds. Evidence was found to suggest that the rosettes ofT. vivaxandT. congolensein the proboscis, and colonies ofT. bruceiparasites in the salivary glands, did not significantly alter the feeding behaviour of the vector.

scholarly journals Age prevalence of trypanosomal infections in female Glossina morsitans morsitans (Diptera : Glossinidae) on the plateau area of eastern Zambia

2007 ◽  
Vol 74 (3) ◽  
Author(s):  
C. Kubi ◽  
M. Billiouw ◽  
P. Van den Bossche
Keyword(s):  
Salivary Glands ◽  
Blood Meal ◽  
Glossina Morsitans Morsitans ◽  
Glossina Morsitans ◽  
Eastern Province ◽  
Plateau Area ◽  
Capita Rate ◽  
Per Capita ◽  
Polynomial Term

Trypanosomal infections in female Glossina morsitans morsitans were investigated in an area in the Eastern Province of Zambia between 1992 and 1994. A total of 4 416 flies were captured, aged using the ovarian ageing method and screened for trypanosomal infections in both the mouthparts, salivary glands and the midgut. Congolense-type infections were identified in 4.8 % of the flies. Vivax-type and immature infections were identified in 1.8 % and 6.8 % of the flies, respectively. The prevalence of con golense-type, vivax-type and immature infections increased with age. For vivax-type infections the age-prevalence relationship could be described by a model assuming a constant per capita rate of infection. For congolense-type and midgut infections, a polynomial term was added to the model significantly improving the fit. The per capita at which flies become infected was significantly higher for immature compared to mature infections. Observations strongly suggest that tsetse acquire new midgut infections at any age and that maturation of these infections is not limited to those obtained during the first blood meal.

Isolation and Characterization of the Tsetse Thrombin Inhibitor: A Potent Antithrombotic Peptide from the Saliva of Glossina morsitans morsitans

1996 ◽  
Vol 54 (5) ◽  
pp. 475-480 ◽  
Author(s):  
Michael Cappello ◽  
David I. Pritchard ◽  
George P. Vlasuk ◽  
Barbara A. Furmidge ◽  
Peter W. Bergum ◽  
...  
Keyword(s):  
Glossina Morsitans Morsitans ◽  
Thrombin Inhibitor ◽  
Glossina Morsitans ◽  
Isolation And Characterization

Serological responses in rabbits used to maintain uninfected, laboratory-reared tsetses (Glossina morsitans morsitans Westwood) (Diptera: Glossinidae)

1979 ◽  
Vol 57 (4) ◽  
pp. 705-710 ◽  
Author(s):  
K. R. Parker
Keyword(s):  
Salivary Gland ◽  
Salivary Glands ◽  
Gel Filtration ◽  
Glossina Morsitans Morsitans ◽  
Immunological Reaction ◽  
Glossina Morsitans ◽  
Anamnestic Response ◽  
Molecular Weights ◽  
Antigen Antibody

Antibodies, reacting with homogenatesof salivary glands, were produced in rabbits exposed to Glossina morsitans morsitans Westwood. Precipitating antibodies and high titres of haemagglutinating antibodies occurred in all exposed rabbits. Precipitating antibodies, identified using immunoelectrophoresis, immunodiffusion, and precipitin ring tests, developed within 11 days of exposure. As many as seven antigen–antibody precipitin arcs were identified using immunoelectrophoresis. All precipitating antigens in the salivary glands had molecular weights greater than 25 000 (determined by Sephadex gel filtration); the salivary gland anticoagulant was not shown to be antigenic. No precipitating immunological reaction occurred between rabbit sera and tsetse hindguts or midguts. Titres of sera from rabbits receiving a second exposure to tsetses, following a period of no exposure, followed an anamnestic response.

Digestive processes of haematophagous insects. XII. Secretion of trypsin and carboxypeptidase B by Glossina morsitans morsitans Westwood (Diptera: Glossinidae)

1977 ◽  
Vol 55 (1) ◽  
pp. 215-222 ◽  
Author(s):  
R. H. Gooding
Keyword(s):  
Bovine Serum Albumin ◽  
Serum Albumin ◽  
Protein Content ◽  
Bovine Serum ◽  
Significant Positive Correlation ◽  
Glossina Morsitans Morsitans ◽  
Trypsin Activity ◽  
Glossina Morsitans ◽  
Carboxypeptidase B ◽  
Positive Correlation

There was a significant positive correlation between protein content and the amounts of trypsin and carboxypeptidase B (CPB) in the digestive portion of the midgut of Glossina morsitans morsitans, 24, 48, 72, and 96 h after feeding on a rabbit. CPB and trypsin activity were also positively correlated. Trypsin and CPB production were stimulated, to varying degrees, by bovine serum albumin (BSA), α-globulin, β-globulin, γ-globulin, and haemoglobin; the greatest response was to BSA. Peptides derived from BSA by trypsin cleavage also stimulated production of trypsin and CPB.

Sign in / Sign up

Export Citation Format

Share Document